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Peroxisomal
A peroxisome () is a membrane-bound organelle, a type of microbody, found in the cytoplasm of virtually all eukaryotic cells. Peroxisomes are oxidative organelles. Frequently, molecular oxygen serves as a co-substrate, from which hydrogen peroxide (H2O2) is then formed. Peroxisomes owe their name to hydrogen peroxide-generating and scavenging activities. They perform key roles in lipid metabolism and the reduction of reactive oxygen species. Peroxisomes are involved in the catabolism of very long chain fatty acids, branched chain fatty acids, bile acid intermediates (in the liver), D-amino acids, and polyamines. Peroxisomes also play a role in the biosynthesis of plasmalogens: ether phospholipids critical for the normal function of mammalian brains and lungs. Peroxisomes contain approximately 10% of the total activity of two enzymes (Glucose-6-phosphate dehydrogenase and 6-Phosphogluconate dehydrogenase) in the pentose phosphate pathway, which is important for energy metab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peroxisome In Rat Neonatal Cardiomyocyte
A peroxisome () is a membrane-bound organelle, a type of microbody, found in the cytoplasm of virtually all eukaryotic cells. Peroxisomes are oxidative organelles. Frequently, molecular oxygen serves as a co-substrate, from which hydrogen peroxide (H2O2) is then formed. Peroxisomes owe their name to hydrogen peroxide-generating and scavenging activities. They perform key roles in lipid metabolism and the reduction of reactive oxygen species. Peroxisomes are involved in the catabolism of very long chain fatty acids, branched chain fatty acids, bile acid intermediates (in the liver), D-amino acids, and polyamines. Peroxisomes also play a role in the biosynthesis of plasmalogens: ether phospholipids critical for the normal function of mammalian brains and lungs. Peroxisomes contain approximately 10% of the total activity of two enzymes (Glucose-6-phosphate dehydrogenase and 6-Phosphogluconate dehydrogenase) in the pentose phosphate pathway, which is important for ener ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasmalogen
Plasmalogens are a class of glycerophospholipid with a plasmenyl group linked to a lipid at the sn-1 position of the glycerol backbone. Plasmalogens are found in multiple domains of life, including Mammal, mammals, Invertebrate, invertebrates, protozoa, and Anaerobic organism, anaerobic bacteria. They are commonly found in cell membranes in the nervous system, nervous, immune system, immune, and cardiovascular systems. In humans, lower levels of plasmalogens are studied in relation to some diseases. Plasmalogens are also associated with adaptations to extreme environments in non-human organisms. Structure Glycerophospholipids of biochemical relevance are divided into three subclasses based on the substitution present at the Glycerophospholipid#Nomenclature and stereochemistry, sn-1 position of the glycerol backbone: acyl_group, acyl, alkyl_group, alkyl and alkenyl_group, alkenyl. Of these, the alkyl and alkenyl moiety in each case form an ether bond, which makes for two types o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbody
A microbody (or cytosome) is a type of organelle that is found in the cells of plants, protozoa, and animals. Organelles in the microbody family include peroxisomes, glyoxysomes, glycosomes and hydrogenosomes. In vertebrates, microbodies are especially prevalent in the liver and kidney. Many membrane bound vesicles called microbodies that contain various enzymes, are present in both plant and animal cells. Structure Microbodies are different type of bodies present in the cytosol, also known as cytosomes. A microbody is usually a vesicle with a spherical shape, ranging from 0.2-1.5 micrometers in diameter."Microbodies." Molecular Biology of Plant Cells. Ed. H. Smith. N.p.: University of California, 1978. 136-54. Print. Microbodies are found in the cytoplasm of a cell, but they are only visible with the use of an electron microscope. They are surrounded by a single phospholipid bilayer membrane and they contain a matrix of intracellular material including enzymes and other prot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glyoxysomes
Glyoxysomes are specialized peroxisomes found in plants (particularly in the fat storage tissues of germinating seeds) and also in filamentous fungi. Seeds that contain fats and oils include corn, soybean, sunflower, peanut and pumpkin. As in all peroxisomes, in glyoxysomes the fatty acids are oxidized to acetyl-CoA by peroxisomal β-oxidation enzymes. When the fatty acids are oxidized hydrogen peroxide (H2O2) is produced as oxygen (O2) is consumed. Thus the seeds need oxygen to germinate. Besides peroxisomal functions, glyoxysomes possess additionally the key enzymes of the glyoxylate cycle ( isocitrate lyase and malate synthase) which accomplish the glyoxylate cycle bypass. Thus, glyoxysomes (as all peroxisomes) contain enzymes that initiate the breakdown of fatty acids and additionally possess the enzymes to produce intermediate products for the synthesis of sugars by gluconeogenesis. The seedling uses these sugars synthesized from fats until it is mature enough to prod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycosome
The glycosome is a membrane A membrane is a selective barrier; it allows some things to pass through but stops others. Such things may be molecules, ions, or other small particles. Membranes can be generally classified into synthetic membranes and biological membranes. Bi ...-enclosed organelle that contains the glycolysis, glycolytic enzymes. The term was first used by Scott and Still in 1968 after they realized that the glycogen in the cell was not static but rather a dynamic molecule. It is found in a few species of protozoa including the Kinetoplastida which include the suborders Trypanosomatida and Bodonina, most notably in the human pathogenic trypanosomes, which can cause African trypanosomiasis, sleeping sickness, Chagas's disease, and leishmaniasis. The organelle is bounded by a single membrane and contains a dense proteinaceous matrix. It is believed to have evolved from the peroxisome. This has been verified by work done on Leishmania genetics. The glycosome is curre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hydrogen Peroxide
Hydrogen peroxide is a chemical compound with the formula . In its pure form, it is a very pale blue liquid that is slightly more viscosity, viscous than Properties of water, water. It is used as an oxidizer, bleaching agent, and antiseptic, usually as a dilute solution (3%–6% by weight) in water for consumer use and in higher concentrations for industrial use. Concentrated hydrogen peroxide, or "high-test peroxide", decomposes explosively when heated and has been used as both a monopropellant and an oxidizer in rocketry. Hydrogen peroxide is a reactive oxygen species and the simplest peroxide, a compound having an oxygen–oxygen single bond. It decomposes slowly into water and elemental oxygen when exposed to light, and rapidly in the presence of organic or reactive compounds. It is typically stored with a Stabilizer (chemistry), stabilizer in a weakly acidic solution in an opaque bottle. Hydrogen peroxide is found in biological systems including the human body. Enzymes that u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ether Phospholipid
In biochemistry, an ether lipid refers to any lipid in which the lipid "tail" group is attached to the glycerol backbone via an ether bond at any position. In contrast, conventional glycerophospholipids and triglycerides are triesters. Structural types include: * Ether phospholipids: phospholipids are known to have ether-linked "tails" instead of the usual ester linkage. ** Ether on sn-1, ester on sn-2: "ether lipids" in the context of bacteria and eukaryotes refer to this class of lipids. Compared to the usual 1,2-diacyl-sn-glycerol (DAG), the sn-1 linkage is replaced with an ester bond.Based on whether the sn-1 lipid is unsaturated next to the ether linkage, they can be further divided into ''alkenyl-acylphospholipids'' ("plasmenylphospholipid", 1-0-alk-1’-enyl-2-acyl-sn-glycerol) and ''alkyl-acylphospholipids'' ("plasmanylphospholipid"). This class of lipids have important roles in human cell signaling and structure. ** Ether on sn-2 and sn-3: this class with flipped chira ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Very Long Chain Fatty Acid
A very-long-chain fatty acid (VLCFA) is a fatty acid with 22 or more carbons. Their biosynthesis occurs in the endoplasmic reticulum. VLCFA's can represent up to a few percent of the total fatty acid content of a cell. Unlike most fatty acids, VLCFAs are too long to be metabolized in the mitochondria, in the endoplasmic reticulum (ER) in plants and must be metabolized in peroxisomes. Certain peroxisomal disorders, such as adrenoleukodystrophy and Zellweger syndrome, can be associated with an accumulation of VLCFAs. Enzymes that produce VLCFAs are the targets of herbicide Herbicides (, ), also commonly known as weed killers, are substances used to control undesired plants, also known as weeds.EPA. February 201Pesticides Industry. Sales and Usage 2006 and 2007: Market Estimates. Summary in press releasMain page f ...s including pyroxasulfone. Major VLCFAs Some of the more common saturated VLCFAs: lignoceric acid (C24), cerotic acid (C26), montanic acid (C28), melissic ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Photorespiration
Photorespiration (also known as the oxidative photosynthetic carbon cycle or C2 cycle) refers to a process in plant physiology, plant metabolism where the enzyme RuBisCO oxygenates RuBP, wasting some of the energy produced by photosynthesis. The desired reaction is the addition of carbon dioxide to RuBP (carboxylation), a key step in the Calvin–Benson cycle, but approximately 25% of reactions by RuBisCO instead add oxygen to RuBP (Oxygenase, oxygenation), creating a product that cannot be used within the Calvin–Benson cycle. This process lowers the efficiency of photosynthesis, potentially lowering photosynthetic output by 25% in C3 carbon fixation, plants. Photorespiration involves a complex network of enzyme reactions that exchange metabolites between chloroplasts, leaf peroxisomes and mitochondria. The oxygenation reaction of RuBisCO is a wasteful process because 3-Phosphoglyceric acid, 3-phosphoglycerate is created at a lower rate and higher metabolic cost compared wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methanol
Methanol (also called methyl alcohol and wood spirit, amongst other names) is an organic chemical compound and the simplest aliphatic Alcohol (chemistry), alcohol, with the chemical formula (a methyl group linked to a hydroxyl group, often abbreviated as MeOH). It is a light, Volatility (chemistry), volatile, colorless and flammable liquid with a distinctive alcoholic odor similar to that of ethanol (potable alcohol), but is more acutely toxic than the latter. Methanol acquired the name wood alcohol because it was once produced through destructive distillation of wood. Today, methanol is mainly produced industrially by hydrogenation of carbon monoxide. Methanol consists of a methyl group linked to a polar hydroxyl group. With more than 20 million tons produced annually, it is used as a Precursor (chemistry), precursor to other commodity chemicals, including formaldehyde, acetic acid, methyl tert-butyl ether, methyl ''tert''-butyl ether, methyl benzoate, anisole, peroxyacids, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trypanosomes
Trypanosomatida is a group of kinetoplastid unicellular organisms distinguished by having only a single flagellum. The name is derived from the Greek language, Greek ''trypano'' (borer) and ''soma'' (body) because of the corkscrew-like motion of some trypanosomatid species. All members are exclusively parasite, parasitic, found primarily in insects. A few genera have life-cycles involving a secondary host, which may be a vertebrate, invertebrate or plant. These include several species that cause major diseases in humans. Some trypanosomatida are intracellular parasites, with the important exception of ''Trypanosoma brucei''. Medical importance The three major human diseases caused by trypanosomatids are; African trypanosomiasis (African trypanosomiasis, sleeping sickness, caused by ''Trypanosoma brucei'' and transmitted by Tsetse fly, tsetse flies), South American trypanosomiasis (Chagas disease, caused by ''Trypanosoma cruzi, T. cruzi'' and transmitted by Triatominae, triatomi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
