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Oneirogenic
An oneirogen, from the Greek ὄνειρος ''óneiros'' meaning "dream" and ''gen'' "to create", is a substance that induces a dream-like state of consciousness. Oneirogens function by altering neural processing in a way that shifts the brain from bottom-up sensory input to top-down generative activity, resembling the mechanisms involved in dreaming. This neural shift is associated with increased internal imagery and reduced responsiveness to external stimuli. Psychedelics—particularly those acting on the 5-HT2A receptor—produce oneirogenic effects by promoting this altered balance of neural signaling. List of oneirogens * ''Calea zacatechichi'' ("''Calea ternifolia''") has been traditionally used in Central America as a believed way to potentiate lucid dreams and perform dream divination. It can promote dreams vivid to the senses, sight, scent, hearing, touch, and taste. May be taken as a tea or smoked. * ''Entada rheedii'' ("African dream bean") * Mugwort, see Artemisi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ibogaine
Ibogaine is a psychoactive indole alkaloid derived from plants such as '' Tabernanthe iboga'', characterized by hallucinogenic and oneirogenic effects. Traditionally used by Central African foragers, it has undergone controversial research for the treatment of substance use disorders. Ibogaine exhibits complex pharmacology by interacting with multiple neurotransmitter systems, notably affecting opioid, serotonin, sigma, and NMDA receptors, while its metabolite noribogaine primarily acts as a serotonin reuptake inhibitor and κ-opioid receptor agonist. The psychoactivity of the root bark of the iboga tree, ''T. iboga'', one of the plants from which ibogaine is extracted, was first discovered by forager tribes in Central Africa, who passed the knowledge to the Bwiti tribe of Gabon. It was first documented in the 19th century for its spiritual use, later isolated and synthesized for its psychoactive properties, briefly marketed in Europe as a stimulant, and ultimately rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calea Zacatechichi
''Calea ternifolia'' ( syn. ''Calea zacatechichi'') is a species of flowering plant in the aster family, Asteraceae. It is native to Mexico and Central America. Its English language common names include bitter-grass, Mexican calea, and dream herb.Simonienko, K., et al. (2013)Psychoactive plant species – actual list of plants prohibited in Poland. ''Psychiatria Polska'' XLVII(3), 499–508. It is used in traditional medicine and ritual in its native range.Ferraz, A., et al. (2009)Pharmacological and genotoxic evaluation of ''Calea clematidea'' and ''Calea uniflora''.''Latin American Journal of Pharmacy'' 28(6), 858-6/ref> Uses In Mexico the plant is used as a herbalism, herbal remedy for dysentery and fever. The Zoque Popoluca people call the plant ''tam huñi'' ("bitter gum") and use it to treat diarrhea and asthma, and the Mixe people know it as ''poop taam ujts'' ("white bitter herb") and use it for stomachache and fever. The Chontal people of Oaxaca reportedly use th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ibogaine
Ibogaine is a psychoactive indole alkaloid derived from plants such as '' Tabernanthe iboga'', characterized by hallucinogenic and oneirogenic effects. Traditionally used by Central African foragers, it has undergone controversial research for the treatment of substance use disorders. Ibogaine exhibits complex pharmacology by interacting with multiple neurotransmitter systems, notably affecting opioid, serotonin, sigma, and NMDA receptors, while its metabolite noribogaine primarily acts as a serotonin reuptake inhibitor and κ-opioid receptor agonist. The psychoactivity of the root bark of the iboga tree, ''T. iboga'', one of the plants from which ibogaine is extracted, was first discovered by forager tribes in Central Africa, who passed the knowledge to the Bwiti tribe of Gabon. It was first documented in the 19th century for its spiritual use, later isolated and synthesized for its psychoactive properties, briefly marketed in Europe as a stimulant, and ultimately rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galantamine
Galantamine is a type of acetylcholinesterase inhibitor. It is an alkaloid extracted from the bulbs and flowers of ''Galanthus nivalis'' (common snowdrop), '' Galanthus caucasicus'' (Caucasian snowdrop), '' Galanthus woronowii'' (Voronov's snowdrop), and other members of the family ''Amaryllidaceae'', such as ''Narcissus'' ( daffodil), '' Leucojum aestivum'' (snowflake), and ''Lycoris'' including '' Lycoris radiata'' (red spider lily). It can also be produced synthetically. Galantamine is primarily known for its potential to slow cognitive decline. It is used clinically for treating early-stage Alzheimer's disease and memory impairments, although it has had limited success with the more advanced condition of dementia. It works by increasing the amount of a type of neurotransmitter named acetylcholine by the inhibiting activity of an enzyme called acetylcholinesterase known for Hydrolysis, breaking down acetylcholine. This elevates and prolongs acetylcholine levels boosting ace ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diphenhydramine
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. Although generally considered sedating, diphenhydramine can cause paradoxical central nervous system stimulation in some individuals, particularly at higher doses. This may manifest as agitation, anxiety, or restlessness rather than sedation. It is a H1 antagonist#First-generation (non-selective, classical), first-generation H1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects. Diphenhydramine is also a potent anticholinergic. It is mainly used to treat allergy, allergies, insomnia, and symptoms of the common cold. It is also less commonly used for tremors in parkinsonism, and nausea. It is taken oral administration, by mouth, injection into a vein, injected into a vein, injection into a muscle, injected into a muscle, or topical medication, applied to the skin. Maximal effect is typically around two hours af ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
West Africa
West Africa, also known as Western Africa, is the westernmost region of Africa. The United Nations geoscheme for Africa#Western Africa, United Nations defines Western Africa as the 16 countries of Benin, Burkina Faso, Cape Verde, The Gambia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Liberia, Mali, Mauritania, Niger, Nigeria, Senegal, Sierra Leone, and Togo, as well as Saint Helena, Ascension and Tristan da Cunha (United Kingdom Overseas Territories, United Kingdom Overseas Territory).Paul R. Masson, Catherine Anne Pattillo, "Monetary union in West Africa (ECOWAS): is it desirable and how could it be achieved?" (Introduction). International Monetary Fund, 2001. The population of West Africa is estimated at around million people as of , and at 381,981,000 as of 2017, of which 189,672,000 were female and 192,309,000 male.United Nations Department of Economic and Social Affairs, Population Division (2017). World Population Prospects: The 2017 Revision, custom data acquired via webs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shrub
A shrub or bush is a small to medium-sized perennial woody plant. Unlike herbaceous plants, shrubs have persistent woody stems above the ground. Shrubs can be either deciduous or evergreen. They are distinguished from trees by their multiple Plant stem, stems and shorter height, less than tall. Small shrubs, less than tall are sometimes termed as subshrubs. Many botany, botanical groups have species that are shrubs, and others that are trees and herbaceous plants instead. Some define a shrub as less than and a tree as over 6 m. Others use as the cutoff point for classification. Many trees do not reach this mature height because of hostile, less than ideal growing conditions, and resemble shrub-sized plants. Others in such species have the potential to grow taller in ideal conditions. For longevity, most shrubs are classified between Perennial plant, perennials and trees. Some only last about five years in good conditions. Others, usually larger and more woody, live beyond ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rainforest
Rainforests are forests characterized by a closed and continuous tree Canopy (biology), canopy, moisture-dependent vegetation, the presence of epiphytes and lianas and the absence of wildfire. Rainforests can be generally classified as tropical rainforests or temperate rainforests, but other types have been described. Estimates vary from 40% to 75% of all biotic community, biotic species being Indigenous (ecology), indigenous to the rainforests. There may be many millions of species of plants, insects and microorganisms still undiscovered in tropical rainforests. Tropical rainforests have been called the "jewels of the Earth" and the "medicine chest (idiom), world's largest pharmacy", because over one quarter of natural medicines have been discovered there. Rainforests as well as endemic rainforest species are rapidly disappearing due to #Deforestation, deforestation, the resulting habitat loss and air pollution, pollution of the atmosphere. Definition Rainforests are cha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perennial Plant
In horticulture, the term perennial (''wikt:per-#Prefix, per-'' + ''wikt:-ennial#Suffix, -ennial'', "through the year") is used to differentiate a plant from shorter-lived annual plant, annuals and biennial plant, biennials. It has thus been defined as a plant that lives more than 2 years. The term is also loosely used to distinguish plants with little or no woody growth (secondary growth in Tree girth measurement, girth) from trees and shrubs, which are also technically ''perennials''. Notably, it is estimated that 94% of plant species fall under the category of perennials, underscoring the prevalence of plants with lifespans exceeding two years in the botanical world. Perennials (especially small flowering plants) that grow and bloom over the spring and summer, die back every autumn and winter, and then return in the spring from their rootstock or other overwintering structure, are known as Herbaceous plant, herbaceous perennials. However, depending on the rigours of the loca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tabernanthe Iboga
''Tabernanthe'' is a genus of flowering plants in the family Apocynaceae, first described as a genus in 1888. It is native to tropical central Africa Africa is the world's second-largest and second-most populous continent after Asia. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 20% of Earth's land area and 6% of its total surfac .... ;Species * '' Tabernanthe elliptica'' (Stapf) Leeuwenb. – Congo-Brazzaville, Zaire, Angola * '' Tabernanthe iboga'' Baill. – Cameroon, Central African Republic, Gabon, Cabinda, Congo-Brazzaville, Zaire, Angola References {{Authority control Apocynaceae genera Rauvolfioideae Taxa named by Henri Ernest Baillon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Muscimol
Muscimol, also known as agarin or pantherine, as well as 5-(aminomethyl)-1,2-oxazol-3-ol, is the principal psychoactive constituent of ''Amanita muscaria'' and '' Amanita pantherina''. Muscimol is an isoxazole alkaloid and a potent and selective orthosteric agonist for the GABAA receptor It displays sedative-hypnotic, depressant and hallucinogenic psychoactivity. It is widely used to study GABAergic function in the brain. Muscimol is under investigation for its potential to treat anxiety, insomnia, and neurological disorders, though its psychoactive nature requires careful regulation. A systematic review and meta-analysis of 22 studies found that muscimol reduces neuropathic pain symptoms, with effects beginning within 15 minutes and lasting up to three hours. Muscimol was tested in small clinical trials between 1977 and 1982 for conditions like schizophrenia, Huntington’s disease, and tardive dyskinesia, but showed limited efficacy and was eventually supplanted by the re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mirtazapine
Mirtazapine, sold under the brand name Remeron among others, is an atypical antidepressant, atypical tetracyclic antidepressant, and as such is used primarily to treat Depression (mood), depression. Its effects may take up to four weeks but can also manifest as early as one to two weeks. It is often used in cases of depression complicated by anxiety or insomnia. The effectiveness of mirtazapine is comparable to other commonly prescribed antidepressants. It is taken oral administration, by mouth. Common side effects include somnolence, sleepiness, vertigo, dizziness, hyperphagia, increased appetite, and weight gain. Serious side effects may include mania, neutropenia, low white blood cell count, and increased suicide among children. Drug withdrawal, Withdrawal symptoms may occur with stopping. It is not recommended together with a monoamine oxidase inhibitor, although evidence supporting the danger of this combination has been challenged. It is unclear if use during pregnancy i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
