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Moment Closure
In probability theory, moment closure is an approximation method used to estimate moments of a stochastic process. Introduction Typically, differential equations describing the ''i-''th moment will depend on the ''(i + 1)''-st moment. To use moment closure, a level is chosen past which all cumulants are set to zero. This leaves a resulting closed system of equations which can be solved for the moments. The approximation is particularly useful in models with a very large state space, such as stochastic population models. History The moment closure approximation was first used by Goodman and Whittle who set all third and higher-order cumulants to be zero, approximating the population distribution with a normal distribution. In 2006, Singh and Hespanha proposed a closure which approximates the population distribution as a log-normal distribution to describe biochemical reactions. Applications The approximation has been used successfully to model the spread of the Afric ...
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Probability Theory
Probability theory is the branch of mathematics concerned with probability. Although there are several different probability interpretations, probability theory treats the concept in a rigorous mathematical manner by expressing it through a set of axioms of probability, axioms. Typically these axioms formalise probability in terms of a probability space, which assigns a measure (mathematics), measure taking values between 0 and 1, termed the probability measure, to a set of outcomes called the sample space. Any specified subset of the sample space is called an event (probability theory), event. Central subjects in probability theory include discrete and continuous random variables, probability distributions, and stochastic processes (which provide mathematical abstractions of determinism, non-deterministic or uncertain processes or measured Quantity, quantities that may either be single occurrences or evolve over time in a random fashion). Although it is not possible to perfectly p ...
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Moment (mathematics)
In mathematics, the moments of a function are certain quantitative measures related to the shape of the function's graph. If the function represents mass density, then the zeroth moment is the total mass, the first moment (normalized by total mass) is the center of mass, and the second moment is the moment of inertia. If the function is a probability distribution, then the first moment is the expected value, the second central moment is the variance, the third standardized moment is the skewness, and the fourth standardized moment is the kurtosis. The mathematical concept is closely related to the concept of moment in physics. For a distribution of mass or probability on a bounded interval, the collection of all the moments (of all orders, from to ) uniquely determines the distribution (Hausdorff moment problem). The same is not true on unbounded intervals ( Hamburger moment problem). In the mid-nineteenth century, Pafnuty Chebyshev became the first person to think sy ...
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Stochastic Process
In probability theory and related fields, a stochastic () or random process is a mathematical object usually defined as a family of random variables. Stochastic processes are widely used as mathematical models of systems and phenomena that appear to vary in a random manner. Examples include the growth of a bacterial population, an electrical current fluctuating due to thermal noise, or the movement of a gas molecule. Stochastic processes have applications in many disciplines such as biology, chemistry, ecology, neuroscience, physics, image processing, signal processing, control theory, information theory, computer science, cryptography and telecommunications. Furthermore, seemingly random changes in financial markets have motivated the extensive use of stochastic processes in finance. Applications and the study of phenomena have in turn inspired the proposal of new stochastic processes. Examples of such stochastic processes include the Wiener process or Brownian motion ...
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Differential Equations
In mathematics, a differential equation is an equation that relates one or more unknown functions and their derivatives. In applications, the functions generally represent physical quantities, the derivatives represent their rates of change, and the differential equation defines a relationship between the two. Such relations are common; therefore, differential equations play a prominent role in many disciplines including engineering, physics, economics, and biology. Mainly the study of differential equations consists of the study of their solutions (the set of functions that satisfy each equation), and of the properties of their solutions. Only the simplest differential equations are solvable by explicit formulas; however, many properties of solutions of a given differential equation may be determined without computing them exactly. Often when a closed-form expression for the solutions is not available, solutions may be approximated numerically using computers. The theor ...
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Cumulant
In probability theory and statistics, the cumulants of a probability distribution are a set of quantities that provide an alternative to the '' moments'' of the distribution. Any two probability distributions whose moments are identical will have identical cumulants as well, and vice versa. The first cumulant is the mean, the second cumulant is the variance, and the third cumulant is the same as the third central moment. But fourth and higher-order cumulants are not equal to central moments. In some cases theoretical treatments of problems in terms of cumulants are simpler than those using moments. In particular, when two or more random variables are statistically independent, the -th-order cumulant of their sum is equal to the sum of their -th-order cumulants. As well, the third and higher-order cumulants of a normal distribution are zero, and it is the only distribution with this property. Just as for moments, where ''joint moments'' are used for collections of random variab ...
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State Space
A state space is the set of all possible configurations of a system. It is a useful abstraction for reasoning about the behavior of a given system and is widely used in the fields of artificial intelligence and game theory. For instance, the toy problem Vacuum World has a discrete finite state space in which there are a limited set of configurations that the vacuum and dirt can be in. A "counter" system, where states are the natural numbers starting at 1 and are incremented over time has an infinite discrete state space. The angular position of an undamped pendulum is a continuous (and therefore infinite) state space. Definition In the theory of dynamical systems, the state space of a discrete system defined by a function ''ƒ'' can be modeled as a directed graph where each possible state of the dynamical system is represented by a vertex with a directed edge from ''a'' to ''b'' if and only if ''ƒ''(''a'') = ''b''. This is known as a state diagram. For a co ...
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Population Model
A population model is a type of mathematical model that is applied to the study of population dynamics. Rationale Models allow a better understanding of how complex interactions and processes work. Modeling of dynamic interactions in nature can provide a manageable way of understanding how numbers change over time or in relation to each other. Many patterns can be noticed by using population modeling as a tool. Ecological population modeling is concerned with the changes in parameters such as population size and age distribution within a population. This might be due to interactions with the environment, individuals of their own species, or other species. Population models are used to determine maximum harvest for agriculturists, to understand the dynamics of biological invasions, and for environmental conservation. Population models are also used to understand the spread of parasites, viruses, and disease. Another way populations models are useful are when species become enda ...
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Normal Distribution
In statistics, a normal distribution or Gaussian distribution is a type of continuous probability distribution for a real-valued random variable. The general form of its probability density function is : f(x) = \frac e^ The parameter \mu is the mean or expectation of the distribution (and also its median and mode), while the parameter \sigma is its standard deviation. The variance of the distribution is \sigma^2. A random variable with a Gaussian distribution is said to be normally distributed, and is called a normal deviate. Normal distributions are important in statistics and are often used in the natural and social sciences to represent real-valued random variables whose distributions are not known. Their importance is partly due to the central limit theorem. It states that, under some conditions, the average of many samples (observations) of a random variable with finite mean and variance is itself a random variable—whose distribution converges to a normal dist ...
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Log-normal Distribution
In probability theory, a log-normal (or lognormal) distribution is a continuous probability distribution of a random variable whose logarithm is normally distributed. Thus, if the random variable is log-normally distributed, then has a normal distribution. Equivalently, if has a normal distribution, then the exponential function of , , has a log-normal distribution. A random variable which is log-normally distributed takes only positive real values. It is a convenient and useful model for measurements in exact and engineering sciences, as well as medicine, economics and other topics (e.g., energies, concentrations, lengths, prices of financial instruments, and other metrics). The distribution is occasionally referred to as the Galton distribution or Galton's distribution, after Francis Galton. The log-normal distribution has also been associated with other names, such as McAlister, Gibrat and Cobb–Douglas. A log-normal process is the statistical realization of the multipl ...
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Africanized Bee
The Africanized bee, also known as the Africanized honey bee and known colloquially as the "killer bee", is a hybrid of the western honey bee (''Apis mellifera''), produced originally by crossbreeding of the East African lowland honey bee (''A. m. scutellata'') with various European honey bee subspecies such as the Italian honey bee ('' A. m. ligustica'') and the Iberian honey bee ('' A. m. iberiensis''). The East African lowland honey bee was first introduced to Brazil in 1956 in an effort to increase honey production, but 26 swarms escaped quarantine in 1957. Since then, the hybrid has spread throughout South America and arrived in North America in 1985. Hives were found in south Texas in the United States in 1990. Africanized honey bees are typically much more defensive than other varieties of honey bees, and react to disturbances faster than European honey bees. They can chase a person a quarter of a mile (400 m); they have killed som ...
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Nematode Infection
A nematode infection is a type of helminthiasis caused by organisms in the nematode phylum. An example is enterobiasis. Several antinematodal agents are available. References External links Helminthiases Infection An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...
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Ruminant
Ruminants ( suborder Ruminantia) are hoofed herbivorous grazing or browsing mammals that are able to acquire nutrients from plant-based food by fermenting it in a specialized stomach prior to digestion, principally through microbial actions. The process, which takes place in the front part of the digestive system and therefore is called foregut fermentation, typically requires the fermented ingesta (known as cud) to be regurgitated and chewed again. The process of rechewing the cud to further break down plant matter and stimulate digestion is called rumination. The word "ruminant" comes from the Latin ''ruminare'', which means "to chew over again". The roughly 200 species of ruminants include both domestic and wild species. Ruminating mammals include cattle, all domesticated and wild bovines, goats, sheep, giraffes, deer, gazelles, and antelopes.Fowler, M.E. (2010).Medicine and Surgery of Camelids, Ames, Iowa: Wiley-Blackwell. Chapter 1 General Biology and Evolution addresses ...
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