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Meta-research
Metascience (also known as meta-research) is the use of scientific methodology to study science itself. Metascience seeks to increase the quality of scientific research while reducing inefficiency. It is also known as "research on research" and "the science of science", as it uses research methods to study how research is done and find where improvements can be made. Metascience concerns itself with all fields of research and has been described as "a bird's eye view of science". In the words of John Ioannidis, "Science is the best thing that has happened to human beings... but we can do it better." In 1966, an early meta-research paper examined the statistical methods of 295 papers published in ten high-profile medical journals. It found that "in almost 73% of the reports read... conclusions were drawn when the justification for these conclusions was invalid." Meta-research in the following decades found many methodological flaws, inefficiencies, and poor practices in research a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Ioannidis
John P. A. Ioannidis ( ; , ; born August 21, 1965) is a Greek-American physician-scientist, writer and Stanford University professor who has made contributions to evidence-based medicine, epidemiology, and clinical research. Ioannidis studies scientific research itself – in other words, meta-research – primarily in clinical medicine and the social sciences. He has served on the editorial board of over twenty scientific journals including ''Journal of the American Medical Association'' (''JAMA''), '' Journal of the National Cancer Institute'' (''JNCI'') and ''The Lancet''. Ioannidis's 2005 essay " Why Most Published Research Findings Are False" was the most-accessed article in the history of Public Library of Science (PLOS) as of 2020, with more than three million views. Ioannidis was a prominent opponent of lockdowns during the COVID-19 pandemic, and he has been accused of promoting conspiracy theories about COVID-19 policies and public health and safety measures. Ear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Methods
Research is creative and systematic work undertaken to increase the stock of knowledge. It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion of past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, economic, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research
Research is creative and systematic work undertaken to increase the stock of knowledge. It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion of past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, eco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Replication Crisis
The replication crisis, also known as the reproducibility or replicability crisis, refers to the growing number of published scientific results that other researchers have been unable to reproduce or verify. Because the reproducibility of empirical results is an essential part of the scientific method, such failures undermine the credibility of theories that build on them and can call into question substantial parts of scientific knowledge. The replication crisis is frequently discussed in relation to psychology and medicine, wherein considerable efforts have been undertaken to reinvestigate the results of classic studies to determine whether they are reliable, and if they turn out not to be, the reasons for the failure. Data strongly indicate that other natural science, natural and social sciences are also affected. The phrase "replication crisis" was coined in the early 2010s as part of a growing awareness of the problem. Considerations of causes and remedies have given rise ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Methodology
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which study the physical world, and the social sciences, which study individuals and societies. While referred to as the formal sciences, the study of logic, mathematics, and theoretical computer science are typically regarded as separate because they rely on deductive reasoning instead of the scientific method as their main methodology. Meanwhile, applied sciences are disciplines that use scientific knowledge for practical purposes, such as engineering and medicine. The history of science spans the majority of the historical record, with the earliest identifiable predecessors to modern science dating to the Bronze Age in Ancient Egypt, Egypt and Mesopotamia (). Their contributions to mathematics, astronomy, and medicine entered and shaped the Gree ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Why Most Published Research Findings Are False
] "Why Most Published Research Findings Are False" is a 2005 essay written by John Ioannidis, a professor at the Stanford School of Medicine, and published in '' PLOS Medicine''. It is considered foundational to the field of metascience. In the paper, Ioannidis argued that a large number, if not the majority, of published medical research papers contain results that cannot be replicated. In simple terms, the essay states that scientists use hypothesis testing to determine whether scientific discoveries are significant. Statistical significance is formalized in terms of probability, with its ''p-''value measure being reported in the scientific literature as a screening mechanism. Ioannidis posited assumptions about the way people perform and report these tests; then he constructed a statistical model which indicates that most published findings are likely false positive results. While the general arguments in the paper recommending reforms in scientific research methodology wer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bias
Bias is a disproportionate weight ''in favor of'' or ''against'' an idea or thing, usually in a way that is inaccurate, closed-minded, prejudicial, or unfair. Biases can be innate or learned. People may develop biases for or against an individual, a group, or a belief. In science and engineering, a bias is a systematic error. Statistical bias results from an unfair sampling of a population, or from an estimation process that does not give accurate results on average. Etymology The word appears to derive from Old Provençal into Old French ''biais'', "sideways, askance, against the grain". Whence comes French ''biais'', "a slant, a slope, an oblique". It seems to have entered English via the game of bowls">English (language)">English via the game of bowls, where it referred to balls made with a greater weight on one side. Which expanded to the figurative use, "a one-sided tendency of the mind", and, at first especially in law, "undue propensity or prejudice". or ballast, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Science
Open science is the movement to make scientific research (including publications, data, physical samples, and software) and its dissemination accessible to all levels of society, amateur or professional. Open science is transparent and accessible knowledge that is shared and developed through collaborative networks. It encompasses practices such as publishing open research, campaigning for open access, encouraging scientists to practice open-notebook science (such as openly sharing data and code), broader dissemination and engagement in science and generally making it easier to publish, access and communicate scientific knowledge. Usage of the term varies substantially across disciplines, with a notable prevalence in the STEM disciplines. Open research is often used quasi-synonymously to address the gap that the denotion of "science" might have regarding an inclusion of the Arts, Humanities and Social Sciences. The primary focus connecting all disciplines is the widesprea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ioannidis (2005) Why Most Published Research Findings Are False
Ioannidis or Ioannides () is a Greek language, Greek surname. The female version of the name is Ioannidou or Ioannides. ''Ioannidis'' or ''Ioannides'' is a patronymic surname which literally means "the son of Ioannis (Yiannis)", thus making it equivalent to English Johnson (surname), Johnson. Notable people with surname Ioannidis or Ioannides include: Men * Alkinoos Ioannidis (born 1969), Cypriot composer and singer * Andreas Ioannides (footballer) (born 1975), Cypriot football player * Dimitrios Ioannides (1923–2010), military officer involved in the Greek military junta of 1967–1974 * Evgenios Ioannidis (born 2001), Greek chess player * Fotis Ioannidis (born 2000), Greek footballer * Georgios Ioannidis (born 1988), Greek footballer * Giannis Ioannidis (1945–2023), former basketball coach and politician * John Ioannidis (born 1965), medical researcher * Matt Ioannidis (born 1994), American football player * Nikolaos Ioannidis (born 1994), Greek footballer * Paul Ioannidis (1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science Studies
Science studies is an interdisciplinarity, interdisciplinary research area that seeks to situate scientific expertise in broad social, historical, and philosophical contexts. It uses various methods to analyze the production, representation and reception of scientific knowledge and its epistemology, epistemic and semiotics, semiotic role. Similarly to cultural studies, science studies are defined by the subject of their research and encompass a large range of different theoretical and methodological perspectives and practices. The interdisciplinary approach may include and borrow methods from the humanities, natural and formal sciences, from scientometrics to ethnomethodology or cognitive science. Science studies have a certain importance for evaluation and science policy. Overlapping with the field of science, technology and society, practitioners study the relationship between science and technology, and the interaction of expert and lay knowledge in the public realm. Sco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Public Library Of Science
PLOS (for Public Library of Science; PLoS until 2012) is a nonprofit publisher of open-access journals in science, technology, and medicine and other scientific literature, under an open-content license. It was founded in 2000 and launched its first journal, ''PLOS Biology'', in October 2003. As of 2024, PLOS publishes 14 academic journals, including 7 journals indexed within the Science Citation Index Expanded, and consequently 7 journals ranked with an impact factor. PLOS journals are included in the Directory of Open Access Journals (DOAJ). PLOS is also a member of the Open Access Scholarly Publishers Association (OASPA), a participating publisher and supporter of the Initiative for Open Citations, and a member of the Committee on Publication Ethics (COPE). History The Public Library of Science began in 2000 with an online petition initiative by Nobel Prize winner Harold Varmus, formerly director of the National Institutes of Health and at that time director of Mem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
