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Isocitric Acid
Isocitric acid is a structural isomer of citric acid. Since citric acid and isocitric acid are structural isomers, they share similar physical and chemical properties. Due to these similar properties, it is difficult to separate the isomers. Salts and esters of isocitric acid are known as isocitrates. The isocitrate anion is a substrate of the citric acid cycle. Isocitrate is formed from citrate with the help of the enzyme aconitase, and is acted upon by isocitrate dehydrogenase. Isocitric acid is commonly used as a marker to detect the authenticity and quality of fruit products, most often citrus juices. In authentic orange juice, for example, the ratio of citric acid to D-isocitric acid is usually less than 130. An isocitric acid value higher than this may be indicative of fruit juice adulteration. Isocitric acid has largely been used as a biochemical agent due to limited amounts. However, isocitric acid has been shown to have pharmaceutical and therapeutic effects. Isocitr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Structural Isomer
In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compound is a compound that contains the same number and type of atoms, but with a different connectivity (i.e. arrangement of bonds) between them. The term metamer was formerly used for the same concept. For example, butanol , methyl propyl ether , and diethyl ether have the same molecular formula but are three distinct structural isomers. The concept applies also to polyatomic ions with the same total charge. A classical example is the cyanate ion and the fulminate ion . It is also extended to ionic compounds, so that (for example) ammonium cyanate and urea are considered structural isomers,William F. Bynum, E. Janet Browne, Roy Porter (2014)''Dictionary of the History of Science'' page 218. and so are methylammonium formate and ammonium acetate . Structural isomerism is the most radical type of isomerism. It is opposed to stereoisomerism, in which the atoms and bon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Yarrowia Lipolytica
''Yarrowia'' is a fungal genus in the family Dipodascaceae. For a while the genus was monotypic, containing the single species ''Yarrowia lipolytica'', a yeast that can use unusual carbon sources, such as hydrocarbons. This has made it of interest for use in industrial microbiology, especially for the production of specialty lipids. Molecular phylogenetics analysis has revealed several other species that have since been added to the genus. In January 2019, ''Yarrowia lipolytica'' yeast biomass was defined by the European Food Safety Authority as a safe novel food – dried and heat‐killed – with the underlying qualifications that it is widespread in nature, present in the typical environment, may be used as food for people over age 3 (3 grams per day for children under age 10, and 6 grams per day for teens and adults), and may be manufactured as a dietary supplement. Biology Habitat ''Yarrowia lipolytica'' has been isolated from various locations (e.g. milled cor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Tricarboxylic Acids
A tricarboxylic acid is an organic chemistry, organic carboxylic acid that contain three carboxyl group, carboxyl functional groups (−COOH). A well-known example is citric acid. Promient examples Some prominent substituted tricarboxylic acids Citric acid, is used in the Citric Acid Cycle, citric acid cyclealso known as the ''tricarboxylic acid'' (''TCA'') ''cycle'' or ''Krebs cycle''which is fundamental to all Aerobic organism, aerobic organisms. Nitrilotriacetic acid (NTA) is a chelating agent for Ca2+, Co2+, Cu2+, and Fe3+. See also * Citric acid cycle (tricarboxylic acid cycle) * Dicarboxylic acid * Mellitic acid References Literature *{{cite journal , title = The Tricarboxylic Acid Cycle, an Ancient Metabolic Network with a Novel Twist. , author = Ryan J. Mailloux, Robin Bériault, Joseph Lemire, Ranji Singh, Daniel R. Chénier, Robert D. Hamel, Vasu D. Appanna , year = 2007 , journal = PLOS ONE , volume = 2 , issue = 8 , pages = e690 , doi = 10.1371/journa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Alpha Hydroxy Acids
Alpha hydroxy carboxylic acids, or α-hydroxy carboxylic acids (AHAs), are a group of carboxylic acids featuring a hydroxy group located ''one'' carbon atom away from the acid group. This structural aspect distinguishes them from beta hydroxy acids, where the functional groups are separated by ''two'' carbon atoms. Notable AHAs include glycolic acid, lactic acid, mandelic acid, and citric acid. α-Hydroxy acids are Strong acids, stronger acids compared to their non-alpha hydroxy counterparts, a property enhanced by internal hydrogen bonding. AHAs serve a dual purpose: industrially, they are utilized as additives in animal feed and as precursors for polymer synthesis. In cosmetics, they are commonly used for their ability to chemically exfoliate the skin. Occurrence Aldonic acids, a type of sugar acid, are a class of naturally occurring hydroxycarboxylic acids. They have the general chemical formula, HO2C(CHOH)''n''CH2OH. Gluconic acid, a particularly common aldonic acid, the oxidi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Malic Acid
Malic acid is an organic compound with the molecular formula . It is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive. Malic acid has two stereoisomeric forms (L- and D-enantiomers), though only the L-isomer exists naturally. The salts and esters of malic acid are known as malates. The malate anion is a metabolic intermediate in the citric acid cycle. Etymology The word 'malic' is derived from Latin , meaning 'apple'. The related Latin word , meaning 'apple tree', is used as the name of the genus ''Malus'', which includes all apples and crabapples; and is the origin of other taxonomic classifications such as Maloideae, Malinae, and Maleae. Biochemistry L-Malic acid is the naturally occurring form, whereas a mixture of L- and D-malic acid is produced synthetically. File:L-Äpfelsäure.svg, L-Malic acid (''S'') File:D-Äpfelsäure.svg, D-Malic acid (''R'') Malate plays an important role i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Tartaric Acid
Tartaric acid is a white, crystalline organic acid that occurs naturally in many fruits, most notably in grapes but also in tamarinds, bananas, avocados, and citrus. Its salt (chemistry), salt, potassium bitartrate, commonly known as cream of tartar, develops naturally in the process of winemaking, fermentation. Potassium bitartrate is commonly mixed with sodium bicarbonate and is sold as baking powder used as a leavening agent in food preparation. The acid itself is added to foods as an antioxidant E-numbers, E334 and to impart its distinctive sour taste. Naturally occurring tartaric acid is a useful raw material in organic synthesis. Tartaric acid, an alpha-hydroxy-carboxylic acid, is diprotic acid, diprotic and aldaric acid, aldaric in acid characteristics and is a dihydroxyl derivative of succinic acid. History Tartaric acid has been known to winemakers for centuries. However, the chemical process for extraction was developed in 1769 by the Sweden, Swedish chemist Carl Wilhel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Chlorocitric Acid
Chlorocitric acid is a organochlorine compound, a derivative of citric acid, belonging to the group of tricarboxylic acids and their derivatives, characterized by the presence of three carboxyl groups. Its chemical formula is . Natural occurrence The acid has been detected in human blood. Chlorocitric acid is not a naturally occurring metabolite; it is found exclusively in individuals who have been exposed to this compound or its derivatives. From a scientific perspective, chlorocitric acid is considered to be part of the human exposome, which encompasses all exposures that individuals encounter throughout their lifetime and their impact on health. These exposures begin before birth and include environmental and occupational factors. Synthesis Chlorocitric acid is obtained by the action of hypochlorous acid on aconitic acid in aqueus solution. Physical properties The acid is uncrystallizible, soluble in water and ether. The compound decomposes when heated, releasing hydrochlor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Fluorocitric Acid
Fluorocitric acid is an organic compound with the chemical formula . It is a fluorinated carboxylic acid derived from citric acid by substitution of one methylene hydrogen by a fluorine atom. The appropriate anion is called fluorocitrate. Fluorocitrate is formed in two steps from fluoroacetate. Fluoroacetate is first converted to fluoroacetyl-CoA by acetyl-CoA synthetase in the mitochondria. Then fluoroacetyl-CoA condenses with oxaloacetate to form fluorocitrate. This step is catalyzed by citrate synthase. Flurocitrate is a metabolite of fluoroacetic acid and is very toxic because it is not processable using aconitase in the citrate cycle (where fluorocitrate takes place of citrate as the substrate). The enzyme is inhibited and the cycle stops working. See also * Chlorocitric acid * Citric acid * Citrate cycle * Fluoroacetic acid * Fluorooleic acid * Isocitric acid Isocitric acid is a structural isomer of citric acid. Since citric acid and isocitric acid are structural iso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Citric Acid
Citric acid is an organic compound with the formula . It is a Transparency and translucency, colorless Weak acid, weak organic acid. It occurs naturally in Citrus, citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in the metabolism of all aerobic organisms. More than two million tons of citric acid Commodity chemicals, are manufactured every year. It is used widely as acidifier, flavoring, preservative, and chelating agent. A citrate is a derivative of citric acid; that is, the salt (chemistry), salts, esters, and the polyatomic ion, polyatomic anion found in solutions and salts of citric acid. An example of the former, a salt is trisodium citrate; an ester is triethyl citrate. When citrate anion, trianion is part of a salt, the formula of the citrate trianion is written as or . Natural occurrence and industrial production Citric acid occurs in a variety of fruits and vegetables, most notably Citrus, citrus fruits. Lemons and Lime ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Citric Acid
Citric acid is an organic compound with the formula . It is a Transparency and translucency, colorless Weak acid, weak organic acid. It occurs naturally in Citrus, citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in the metabolism of all aerobic organisms. More than two million tons of citric acid Commodity chemicals, are manufactured every year. It is used widely as acidifier, flavoring, preservative, and chelating agent. A citrate is a derivative of citric acid; that is, the salt (chemistry), salts, esters, and the polyatomic ion, polyatomic anion found in solutions and salts of citric acid. An example of the former, a salt is trisodium citrate; an ester is triethyl citrate. When citrate anion, trianion is part of a salt, the formula of the citrate trianion is written as or . Natural occurrence and industrial production Citric acid occurs in a variety of fruits and vegetables, most notably Citrus, citrus fruits. Lemons and Lime ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Dextrorotation And Levorotation
Optical rotation, also known as polarization rotation or circular birefringence, is the rotation of the orientation of the plane of polarization about the optical axis of linearly polarized light as it travels through certain materials. Circular birefringence and circular dichroism are the manifestations of optical activity. Optical activity occurs only in chiral materials, those lacking microscopic mirror symmetry. Unlike other sources of birefringence which alter a beam's state of polarization, optical activity can be observed in fluids. This can include gases or solutions of chiral molecules such as sugars, molecules with helical secondary structure such as some proteins, and also chiral liquid crystals. It can also be observed in chiral solids such as certain crystals with a rotation between adjacent crystal planes (such as quartz) or metamaterials. When looking at the source of light, the rotation of the plane of polarization may be either to the right (dextrorotatory ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
