Irradiation
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Irradiation
Irradiation is the process by which an object is exposed to radiation. An irradiator is a device used to expose an object to radiation, most often gamma radiation, for a variety of purposes. Irradiators may be used for sterilizing medical and pharmaceutical supplies, preserving foodstuffs, alteration of gemstone colors, studying radiation effects, eradicating insects through sterile male release programs, or calibrating thermoluminescent dosimeters (TLDs). The exposure can originate from various sources, including natural sources. Most frequently the term refers to ionizing radiation, and to a level of radiation that will serve a specific purpose, rather than radiation exposure to normal levels of background radiation. The term irradiation usually excludes the exposure to non-ionizing radiation, such as infrared, visible light, microwaves from cellular phones or electromagnetic waves emitted by radio and television receivers and power supplies. Applications Sterilization If ...
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Food Irradiation
Food irradiation (sometimes American English: radurization; British English: radurisation) is the process of exposing food and food packaging to ionizing radiation, such as from gamma rays, x-rays, or electron beams. Food irradiation improves food safety and extends product shelf life (preservation) by effectively destroying organisms responsible for spoilage and foodborne illness, inhibits sprouting or ripening, and is a means of controlling insects and invasive pests. In the United States, consumer perception of foods treated with irradiation is more negative than those processed by other means. The U.S. Food and Drug Administration (FDA), the World Health Organization (WHO), the Centers for Disease Control and Prevention (CDC), and U.S. Department of Agriculture (USDA) have performed studies that confirm irradiation to be safe.World Health Organization. Safety and Nutritional Adequacy of Irradiated Food. Geneva, Switzerland: World Health Organization; 1994 In order for a ...
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Sterilization (microbiology)
Sterilization () refers to any process that removes, kills, or deactivates all forms of life (particularly microorganisms such as fungi, bacteria, spores, and unicellular eukaryotic organisms) and other biological agents (such as prions or viruses) present in fluid or on a specific surface or object. Sterilization can be achieved through various means, including heat, chemicals, irradiation, high pressure food preservation, high pressure, and filtration. Sterilization is distinct from disinfection, sanitization, and pasteurization, in that those methods reduce rather than eliminate all forms of life and biological agents present. After sterilization, fluid or an object is referred to as being sterile or aseptic. Applications Foods One of the first steps toward modernized sterilization was made by Nicolas Appert, who discovered that application of heat over a suitable period of time slowed the decay of foods and various liquids, preserving them for safe consumption for a longer t ...
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Radiation Therapy
Radiation therapy or radiotherapy (RT, RTx, or XRT) is a therapy, treatment using ionizing radiation, generally provided as part of treatment of cancer, cancer therapy to either kill or control the growth of malignancy, malignant cell (biology), cells. It is normally delivered by a linear particle accelerator. Radiation therapy may be cure, curative in a number of types of cancer if they are localized to one area of the body, and have not metastasis, spread to other parts. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the canc ...
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Swift Heavy Ions
Swift heavy ions are the components of a type of particle beam with high enough energy that electronic stopping dominates over nuclear stopping.M. Toulemonde, W. Assmann, C. Dufour, A. Meftah, F. Studer, and C. Trautmann, Experimental phenomena and thermal spike model description of ion tracks in amorphisable inorganic insulators, Mat. Fys. Medd. Kong. Dan. Vid. Selsk. 52, 263 (2006). They are accelerated in particle accelerators to very high energies, typically in the MeV or GeV range and have sufficient energy and mass to penetrate solids on a straight line. In many solids swift heavy ions release sufficient energy to induce permanently modified cylindrical zones, so-called ion tracks. If the irradiation is carried out in an initially crystalline material, ion tracks consist of an amorphous cylinder. Ion tracks can be produced in many amorphizing materials, but not in pure metals, where the high electronic heat conductivity dissipates away the electronic heating before the i ...
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Exposure (radiation)
Radiation exposure is a measure of the ionization of air due to ionizing radiation from photons. It is defined as the electric charge freed by such radiation in a specified volume of air divided by the mass of that air. As of 2007, "medical radiation exposure" was defined by the International Commission on Radiological Protection as exposure incurred by people as part of their own medical or dental diagnosis or treatment; by persons, other than those occupationally exposed, knowingly, while voluntarily helping in the support and comfort of patients; and by volunteers in a programme of biomedical research involving their exposure. Common medical tests and treatments involving radiation include X-rays, CT scans, mammography, lung ventilation and perfusion scans, bone scans, cardiac perfusion scan, angiography, radiation therapy, and more. Each type of test carries its own amount of radiation exposure. There are two general categories of adverse health effects caused by radiation e ...
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Ionizing Radiation
Ionizing (ionising) radiation, including Radioactive decay, nuclear radiation, consists of subatomic particles or electromagnetic waves that have enough energy per individual photon or particle to ionization, ionize atoms or molecules by detaching electrons from them. Some particles can travel up to 99% of the speed of light, and the electromagnetic waves are on the high-energy portion of the electromagnetic spectrum. Gamma rays, X-rays, and the higher energy vacuum ultraviolet, ultraviolet part of the electromagnetic spectrum are ionizing radiation; whereas the lower energy ultraviolet, visible light, infrared, microwaves, and radio waves are non-ionizing radiation. Nearly all types of laser light are non-ionizing radiation. The boundary between ionizing and non-ionizing radiation in the ultraviolet area cannot be sharply defined, as different molecules and atoms ionize at Ionization energies of the elements (data page), different energies. The energy of ionizing radiation starts ...
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Blood Transfusion
Blood transfusion is the process of transferring blood products into a person's Circulatory system, circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, blood plasma, plasma, platelets, and other clotting factors. White blood cells are transfused only in very rare circumstances, since granulocyte transfusion has limited applications. Whole blood has come back into use in the Major trauma, trauma setting. Red blood cells (RBC) contain hemoglobin and supply the Cell (biology), cells of the body with oxygen. White blood cells are not commonly used during transfusions, but they are part of the immune system and also fight infections. Plasma is the "yellowish" liquid part of blood, which acts as a buffer and contains proteins and other important substances needed for the body's overall ...
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Ion Implantation
Ion implantation is a low-temperature process by which ions of one element are accelerated into a solid target, thereby changing the target's physical, chemical, or electrical properties. Ion implantation is used in semiconductor device fabrication and in metal finishing, as well as in materials science research. The ions can alter the elemental composition of the target (if the ions differ in composition from the target) if they stop and remain in the target. Ion implantation also causes chemical and physical changes when the ions impinge on the target at high energy. The crystal structure of the target can be damaged or even destroyed by the energetic collision cascades, and ions of sufficiently high energy (tens of MeV) can cause nuclear transmutation. General principle Ion implantation equipment typically consists of an ion source, where ions of the desired element are produced, an accelerator, where the ions are electrostatically accelerated to a high energy or usin ...
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Heptamethine Dyes
Heptamethine dyes are a subclass of chemical compounds within the cyanine dye family and have many uses as fluorescent dyes, particularly in biomedical imaging, the development of theranostics, the individualized treatment of cancerous patients with the aid of PDT, co-administration with other drugs, and irradiation.F. Pene, E. Courtine, A. Cariou, J.P. Mira. Toward theranostics. Crit Care Med, 37 (2009), pp. S50–S58 The characteristics of heptamethine dyes can be understood by comparing research data on different dyes within the family. For example, the IR-780 dye exhibits a peak spectral absorption of around 780 nm. Optical properties The absorption and fluorescence spectrum of heptamethine dyes are in the near infrared region and vary largely on the solvent and concentration. IR-808 absorbs mainly between 775 nm and 796 nm and emits fluorescence between 808 nm and 827 nm with a large red shift as expected in the serum sample. These absorptio ...
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Electron Beam Processing
The electron (, or in nuclear reactions) is a subatomic particle with a negative one elementary electric charge. It is a fundamental particle that comprises the ordinary matter that makes up the universe, along with up and down quarks. Electrons are extremely lightweight particles that orbit the positively charged nucleus of atoms. Their negative charge is balanced by the positive charge of protons in the nucleus, giving atoms their overall neutral charge. Ordinary matter is composed of atoms, each consisting of a positively charged nucleus surrounded by a number of orbiting electrons equal to the number of protons. The configuration and energy levels of these orbiting electrons determine the chemical properties of an atom. Electrons are bound to the nucleus to different degrees. The outermost or valence electrons are the least tightly bound and are responsible for the formation of chemical bonds between atoms to create molecules and crystals. These valence electrons als ...
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X-rays
An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ranging from 10 Nanometre, nanometers to 10 Picometre, picometers, corresponding to frequency, frequencies in the range of 30 Hertz, petahertz to 30 Hertz, exahertz ( to ) and photon energies in the range of 100 electronvolt, eV to 100 keV, respectively. X-rays were discovered in 1895 in science, 1895 by the German scientist Wilhelm Röntgen, Wilhelm Conrad Röntgen, who named it ''X-radiation'' to signify an unknown type of radiation.Novelline, Robert (1997). ''Squire's Fundamentals of Radiology''. Harvard University Press. 5th edition. . X-rays can penetrate many solid substances such as construction materials and living tissue, so X-ray radiography is widely used in medical diagnostics (e.g., checking for Bo ...
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