Infectious Hypodermal And Hematopoietic Necrosis
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Infectious Hypodermal And Hematopoietic Necrosis
Infectious hypodermal and hematopoietic necrosis (IHHN) is a parvoviral disease of penaeid shrimp that causes mass mortality (up to 90%) among the Western blue shrimp (''Penaeus stylirostris'') and severe deformations in the Pacific white shrimp ('' P. vannamei''). It occurs in Pacific farmed and wild shrimp, but not in wild shrimp on the Atlantic coast of the Americas. The shrimp-farming industry has developed several broodstocks of both ''P. stylirostris'' and ''P. vannamei'' that are resistant against IHHN infection. The disease is caused by a single-stranded DNA virus A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and t ... known as Infectious hypodermal and hematopoietic necrosis (IHHN) virus, the smallest of the known penaeid shrimp viruses (22  nm).Gulf States Marine Fishe ...
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Parvoviridae
Parvoviruses are a family of animal viruses that constitute the family ''Parvoviridae''. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the protein the viral capsid is made of. The coding portion of the genome is flanked by telomeres at each end that form into Stem-loop, hairpin loops that are important during replication. Parvovirus virions are small compared to most viruses, at 23–28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface. Parvoviruses enter a host cell by endocytosis, travelling to the nucleus where they wait until the cell enters its replication stage. At that point, the genome is uncoated and the coding portion is replicated. Viral messenger RNA (mRNA) is then Transcription (biology), transcribed and Translation (biology), translated, resulting in NS1 initiating replication. During replication, the hairpi ...
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