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Human Herpes Virus
''Orthoherpesviridae'', previously named and more widely known as ''Herpesviridae'', is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are commonly known as herpesviruses. The family name is derived from the Greek word ἕρπειν ( 'to creep'), referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster (shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established ''Herpesvirus'' as a genus with 23 viruses among four groups. Since then, the number of identified herpesviruses has grown to more than 100. Herpesviruses can cause both latent and lytic infections. Nine herpesvirus types are known to primarily infect humans, at least five of which are extremely widespread among most human populations, and which cause common diseases: herpes simplex 1 and 2 (HSV-1 and HSV-2, also known a ...
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Family (biology)
Family (, : ) is one of the eight major hierarchical taxonomic ranks in Linnaean taxonomy. It is classified between order and genus. A family may be divided into subfamilies, which are intermediate ranks between the ranks of family and genus. The official family names are Latin in origin; however, popular names are often used: for example, walnut trees and hickory trees belong to the family Juglandaceae, but that family is commonly referred to as the "walnut family". The delineation of what constitutes a family—or whether a described family should be acknowledged—is established and decided upon by active taxonomists. There are not strict regulations for outlining or acknowledging a family, yet in the realm of plants, these classifications often rely on both the vegetative and reproductive characteristics of plant species. Taxonomists frequently hold varying perspectives on these descriptions, leading to a lack of widespread consensus within the scientific community ...
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Human Herpesvirus 7
Human herpesvirus 7 (HHV-7) is one of nine known members of the ''Herpesviridae'' family that infects humans. HHV-7 is a member of ''Betaherpesvirinae'', a subfamily of the ''Herpesviridae'' that also includes HHV-6 and ''Cytomegalovirus'' (HHV-5 or HCMV). HHV-7 often acts together with HHV-6, and the viruses together are sometimes referred to by their genus, '' Roseolovirus''. HHV-7 was first isolated in 1990 from CD4+ T cells taken from peripheral blood lymphocytes. Signs and symptoms Both HHV-6B and HHV-7, as well as other viruses, can cause a skin condition in infants known as exanthema subitum, although HHV-7 causes the disease less frequently than HHV-6B. HHV-7 infection also leads to or is associated with a number of other symptoms, including acute febrile respiratory disease, fever, rash, vomiting, diarrhea, low lymphocyte counts, and febrile seizures, though most often no symptoms present at all. There are indications that HHV-7 can contribute to the development ...
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Varicellovirus
''Varicellovirus'' (var′i-sel′ō-vi′rŭs) is a genus of viruses belonging to subfamily ''Alphaherpesvirinae'', a member of family ''Herpesviridae''. Humans and other mammals serve as natural hosts. There are 19 species in this genus. Diseases associated with this genus include: HHV-3—chickenpox (varicella) and shingles; BoHV-1—infectious bovine rhinotracheitis/infectious pustular vulvovaginitis (IPV); and SuHV-1 (also known as pseudorabies virus)— Aujesky's disease. Species The following 20 species are assigned to the genus in ICTV 2022 * '' Varicellovirus bovinealpha1'' * '' Varicellovirus bovinealpha5'' * '' Varicellovirus bubalinealpha1'' * '' Varicellovirus canidalpha1'' * '' Varicellovirus caprinealpha1'' * '' Varicellovirus cercopithecinealpha9'' * '' Varicellovirus cervidalpha1'' * '' Varicellovirus cervidalpha2'' * '' Varicellovirus cervidalpha3'' * '' Varicellovirus equidalpha1'' * '' Varicellovirus equidalpha3'' * '' Varicellovirus equidalpha4'' * Varic ...
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Simplexvirus
''Simplexvirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Humans and mammals A mammal () is a vertebrate animal of the class Mammalia (). Mammals are characterised by the presence of milk-producing mammary glands for feeding their young, a broad neocortex region of the brain, fur or hair, and three middle e ... serve as natural hosts. Diseases associated with this genus include skin vesicles or mucosal ulcers, rarely encephalitis, and meningitis. Species The following 17 species are assigned to the genus in ICTV 2022: * '' Simplexvirus atelinealpha1'' * '' Simplexvirus bovinealpha2'' * '' Simplexvirus cercopithecinealpha2'' * '' Simplexvirus humanalpha1'' * '' Simplexvirus humanalpha2'' * '' Simplexvirus leporidalpha4'' * '' Simplexvirus macacinealpha1'' * '' Simplexvirus macacinealpha2'' * '' Simplexvirus macacinealpha3'' * '' Simplexvirus macropodidalpha1'' * '' Simplexvirus ...
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Scutavirus
''Scutavirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae ''Alphaherpesvirinae'' is a subfamily of viruses in the family ''Herpesviridae'', primarily distinguished by reproducing more quickly than other subfamilies in the ''Herpesviridae''. In animal virology the most important herpesviruses belong to ...''. Turtles and tortoises serve as natural hosts. Diseases associated with this genus include fibropapillomatosis. Species The genus consists of the following species: * '' Scutavirus chelonidalpha5'', also called Chelonid alphaherpesvirus 5 * '' Scutavirus testudinidalpha3'', also called Testudinid alphaherpesvirus 3 Structure Viruses in ''Scutavirus'' are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented. Life cycle Viral replication is nuclear, and is lyso ...
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Mardivirus
''Mardivirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Chickens, turkeys, and quail serve as natural hosts. There are six species in this genus. Diseases associated with this genus include: Marek's disease, which causes asymmetric paralysis of one or more limbs, neurological symptoms, and development of multiple lymphomas that manifest as solid tumors. Gallid herpesvirus 2 (also known as Marek's disease virus) is the only one of these viruses known to be pathogenic and due to the antigenic similarity between the three viruses the other two have been used to vaccinate against Marek's disease. These viruses have double stranded DNA genomes with no RNA intermediate. Species The genus consists of the following six species: * ''Mardivirus anatidalpha1'', also called Anatid alphaherpesvirus 1 * ''Mardivirus columbidalpha1'', also called Columbid alphaherpesvirus 1 * ''Mardivirus gallidalpha2'', a ...
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Iltovirus
''Iltovirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail Quail is a collective name for several genera of mid-sized birds generally placed in the order Galliformes. The collective noun for a group of quail is a flock, covey, or bevy. Old World quail are placed in the family Phasianidae, and New ... serve as natural hosts. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious laryngotracheitis; psHV-1: Pacheco's disease. Species The genus consists of the following species: * '' Iltovirus cacatuidalpha2'' * '' Iltovirus gallidalpha1'', also called Gallid alphaherpesvirus 1 * '' Iltovirus psittacidalpha1'', also called Psittacid alphaherpesvirus 1 * '' Iltovirus psittacidalpha5'' Structure Viruses in ''Iltovirus'' are enveloped, with icosahedral, spherical to pleomorphic, a ...
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Alphaherpesvirinae
''Alphaherpesvirinae'' is a subfamily of viruses in the family ''Herpesviridae'', primarily distinguished by reproducing more quickly than other subfamilies in the ''Herpesviridae''. In animal virology the most important herpesviruses belong to the Alphaherpesvirinae. Pseudorabies virus is the causative agent of Aujeszky's disease in pigs, and '' Bovine herpesvirus 1'' is the causative agent of bovine infectious rhinotracheitis and pustular vulvovaginitis. Mammals serve as natural hosts. There are currently 45 species in this subfamily, divided among 5 genera, with one species unassigned to a genus. Diseases associated with this subfamily include: HHV-1 and HHV-2: skin vesicles or mucosal ulcers, rarely encephalitis and meningitis, HHV-3: chickenpox (varicella) and shingles, GaHV-2: Marek's disease. Genera ''Alphaherpesvirinae'' consists of the following five genera: * '' Iltovirus'' * ''Mardivirus'' * '' Scutavirus'' * '' Simplexvirus'' * '' Varicellovirus'' The species ...
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Pustular Vulvovaginitis
Bovine alphaherpesvirus 1 (BoHV-1) is a virus of the family ''Herpesviridae'' and the subfamily ''Alphaherpesvirinae'', known to cause several diseases worldwide in cattle, including rhinotracheitis, vaginitis, balanoposthitis, abortion, conjunctivitis, and enteritis. BoHV-1 is also a contributing factor in shipping fever, also known as bovine respiratory disease (BRD). It is spread horizontally through sexual contact, artificial insemination, and aerosol transmission and it may also be transmitted vertically across the placenta. BoHV-1 can cause both clinical and subclinical infections, depending on the virulence of the strain. Although these symptoms are mainly non-life-threatening it is an economically important disease as infection may cause a drop in production and affect trade restrictions. Like other herpesviruses, BoHV-1 causes a lifelong latent infection and sporadic shedding of the virus. The sciatic nerve and trigeminal nerve are the sites of latency. A reactiv ...
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Bovine Herpesvirus 1
Bovine alphaherpesvirus 1 (BoHV-1) is a virus of the family ''Herpesviridae'' and the subfamily ''Alphaherpesvirinae'', known to cause several diseases worldwide in cattle, including rhinotracheitis, vaginitis, balanoposthitis, abortion, conjunctivitis, and enteritis. BoHV-1 is also a contributing factor in shipping fever, also known as bovine respiratory disease (BRD). It is spread horizontally through sexual contact, artificial insemination, and aerosol transmission and it may also be transmitted vertically across the placenta. BoHV-1 can cause both clinical and subclinical infections, depending on the virulence of the strain. Although these symptoms are mainly non-life-threatening it is an economically important disease as infection may cause a drop in production and affect trade restrictions. Like other herpesviruses, BoHV-1 causes a lifelong latent infection and sporadic shedding of the virus. The sciatic nerve and trigeminal nerve are the sites of latency. A reactivate ...
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Aujeszky's Disease
Aujeszky's disease, usually called pseudorabies in the United States, is a viral disease in swine that is endemic in most parts of the world. It is caused by pseudorabies virus (PRV). Aujeszky's disease is considered to be the most economically important viral disease of swine in areas where classical swine fever ( hog cholera) has been eradicated. Other mammals, such as cattle, sheep, goats, cats, dogs, and raccoons, are also susceptible. The disease is usually fatal in these animal species. Research on PRV in pigs has pioneered animal disease control with genetically modified vaccines. PRV is now used in model studies of basic processes during lytic herpesvirus infection, and for unravelling molecular mechanisms of herpesvirus neurotropism. History In 1902, a Hungarian veterinarian, Aladár Aujeszky, demonstrated a new infectious agent in a dog, ox, and cat, and showed it caused the same disease in swine and rabbits. In the following decades the infection was found in ...
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