|
Horsfiline
Horsfiline is an oxindole alkaloid found in the plant '' Horsfieldia superba'', which is used in traditional herbal medicine. It has analgesic effects and has been the subject of research both to produce it synthetically by convenient routes and to develop analogues and derivatives which may have improved analgesic effects. It is a member of the spiroindolone The spiroindolones are a class of compounds in which an indolone ring is substituted with another ring in a spiro arrangement. Alkaloids in this class include horsfiline, rhynchophylline, gelsemine, carapanaubine, and maremycin E. Spiroind ... class. Elacomine has a similar chemical structure. References {{reflist Phenol ethers Lactams Oxindoles Pyrrolidine alkaloids Spiro compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Spiroindolone
The spiroindolones are a class of compounds in which an indolone ring is substituted with another ring in a spiro arrangement. Alkaloids in this class include horsfiline, rhynchophylline, gelsemine, carapanaubine, and maremycin E. Spiroindolones are also an emerging class of antimalarial drugs whose mode of action is to inhibit protein synthesis in the target parasite. The most advanced compound in this class in terms of drug development Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regu ... is cipargamin (NITD609). References Antimalarial agents Spiro compounds {{antiinfective-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Horsfieldia Superba
''Horsfieldia'' is a genus of evergreen trees. The genus consists of about 100 species and is distributed across South Asia, from India to the Philippines and Papua New Guinea. Some species are used for timber. Species in the genus sometimes contain alkaloids, including horsfiline, which has analgesic effects. Species ''Plants of the World Online'' currently (February 2024) includes: # ''Horsfieldia ampla'' Markgr. # ''Horsfieldia ampliformis'' W.J.de Wilde # ''Horsfieldia amplomontana'' W.J.de Wilde # ''Horsfieldia amygdalina'' (Wall.) Warb. # ''Horsfieldia androphora'' W.J.de Wilde # ''Horsfieldia angularis'' W.J.de Wilde # ''Horsfieldia ardisiifolia'' (A.DC.) Warb. # ''Horsfieldia aruana'' (Blume) W.J.de Wilde # ''Horsfieldia atjehensis'' W.J.de Wilde # ''Horsfieldia australiana'' S.T.Blake # ''Horsfieldia basifissa'' W.J.de Wilde # ''Horsfieldia borneensis'' W.J.de Wilde # ''Horsfieldia brachiata'' (King) Warb. # ''Horsfieldia carnosa'' Warb. # ''Horsfieldia clavata'' W.J.de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
