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History Of Intersex Surgery
The history of intersex surgery is intertwined with the development of the specialities of pediatric surgery, pediatric urology, and pediatric endocrinology, with our increasingly refined understanding of sexual differentiation, with the development of political advocacy groups united by a human qualified analysis, and in the last decade by doubts as to efficacy, and controversy over when and even whether some procedures should be performed. Prior to the medicalization of intersex, Canon and common law referred to a person's sex as male, female or hermaphrodite, with legal rights as male or female depending on the characteristics that appeared most dominant. The foundation of common law, the ''Institutes of the Lawes of England'' described how a hermaphrodite could inherit "either as male or female, according to that kind of sexe which doth prevaile." Single cases have been described by legal cases sporadically over the centuries. Diodorus Siculus is the first to record medical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pediatric Surgery
Pediatric surgery is a subspecialty of surgery involving the surgery of fetuses, infants, children, adolescents, and young adults. History Pediatric surgery arose in the middle of the 1879 century as the surgical care of birth defects required novel techniques and methods, and became more commonly based at children's hospitals. One of the sites of this innovation was the Children's Hospital of Philadelphia. Beginning in the 1940s under the surgical leadership of C. Everett Koop, newer techniques for endotracheal anesthesia of infants allowed surgical repair of previously untreatable birth defects. By the late 1970s, the infant death rate from several major congenital malformation syndromes had been reduced to near zero. Specialties Subspecialties of pediatric surgery itself include: neonatal surgery and fetal surgery. Other areas of surgery also have pediatric specialties of their own that require further training during the residencies and in a fellowship: pediatric cardio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paul Of Aegina
Paul of Aegina or Paulus Aegineta (; Aegina, ) was a 7th-century Byzantine Greek physician best known for writing the encyclopedia, medical encyclopedia ''Medical Compendium in Seven Books.'' He is considered the “Father of Early Medical Writing”. For many years in the Byzantine Empire, his works contained the sum of all available medical knowledge and was unrivaled in its accuracy and completeness. Life Nothing is known about his life, except that he was born in the island of Aegina Aegina (; ; ) is one of the Saronic Islands of Greece in the Saronic Gulf, from Athens. Tradition derives the name from Aegina (mythology), Aegina, the mother of the mythological hero Aeacus, who was born on the island and became its king. ..., and that he travelled a good deal, visiting, among other places, Alexandria. He is sometimes called ''Iatrosophistes'' and ''Periodeutes'', a word which probably means a physician who travelled from place to place in the exercise of his profession. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormone
A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior. Hormones are required for the normal development of animals, plants and fungi. Due to the broad definition of a hormone (as a signaling molecule that exerts its effects far from its site of production), numerous kinds of molecules can be classified as hormones. Among the substances that can be considered hormones, are eicosanoids (e.g. prostaglandins and thromboxanes), steroids (e.g. Estrogen, oestrogen and brassinosteroid), amino acid derivatives (e.g. epinephrine and auxin), protein or peptides (e.g. insulin and CLE peptides), and gases (e.g. ethylene and nitric oxide). Hormones are used to communicate between organ (anatomy), organs and Tissue (biology), tissues. In vertebrates, hormones are responsible for regulating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virilization
Virilization or masculinization is the biological development of adult male characteristics in young males or females. Most of the changes of virilization are produced by androgens. Virilization is a medical term commonly used in three medical and biology of sex contexts: prenatal biological sexual differentiation, the postnatal changes of typical chromosomal male (46, XY) puberty, and excessive androgen effects in typical chromosomal females (46, XX). It is also the intended result of androgen replacement therapy in males with delayed puberty and low testosterone. Prenatal virilization In the prenatal period, virilization refers to closure of the perineum, thinning and wrinkling (rugation) of the scrotum, growth of the penis, and closure of the urethral groove to the tip of the penis. In this context, ''masculinization'' is synonymous with ''virilization''. Prenatal virilization of XX fetuses and undervirilization of XY fetuses are common causes of ambiguous genitalia suc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frederick Bartter
Frederic Crosby Bartter (September 10, 1914 – May 5, 1983) was an American endocrinologist best known for his work on hormones affecting the kidney and his discovery of syndrome of inappropriate antidiuretic hormone reproduced in and Bartter syndrome. Reproduced in He had a separate interest in mushroom poisoning. Early life He was born to an English Anglican minister and his American wife in Manila, Philippines, and grew up in the mountain village of Baguio. At the age of 13 he was sent, together with his brother, to attend the Lenox School until 1930. After teaching in the Philippines for a year, he enrolled at Harvard where he obtained a BA in 1935. After a year at Harvard School of Public Health he entered Harvard Medical School, graduating there in 1940. Internships took place at Roosevelt Hospital in New York City in 1941 and 1942. Army service led to academic work on blood products and onchocerciasis (river blindness, a tropical disease). Boston He became a research f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lawson Wilkins
Lawson Wilkins (March 6, 1894 - September 27, 1963) was an American pediatric endocrinologist. He is known along with John Money for pioneering surgeries for visibly intersex newborns. At the time, intersex anatomy was understood virtually exclusively as a birth defect as opposed to a nonpathological anatomical variation. Physicians who trained under Wilkins would later go on to found the Pediatric Endocrine Society, with the society's name originally including a tribute to him. Biography Lawson Wilkins was born on March 6, 1894 in Baltimore, Maryland. His father was also a physician. After completing his service in World War I, he studied at the Johns Hopkins School of Medicine. He completed his pediatric residency at Yale University before returning to practice in his hometown of Baltimore. Honors *Borden Award, American Academy of Pediatrics (1953) *Amory Prize, American Academy of Arts and Sciences (1955) *Koch Award, Endocrine Society (1961) *John Howland Award, American P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Adrenal Hyperplasia
Congenital adrenal hyperplasia (CAH) is a group of Genetic disorder#Autosomal recessive, autosomal recessive disorders characterized by impaired cortisol synthesis. It results from the deficiency of one of the five enzymes required for the Biosynthesis, synthesis of cortisol in the adrenal cortex. Most of these disorders involve excessive or deficient production of hormones such as glucocorticoids, mineralocorticoids, or sex steroids, and can alter development of primary sex characteristic, primary or secondary sex characteristics in some affected infants, children, or adults. It is one of the most common autosomal recessive disorders in humans. Types CAH can occur in various forms. The clinical presentation of each form is different and depends to a large extent on the underlying enzyme defect, its precursor retention, and deficient products. Classical forms appear in infancy and nonclassical forms appear in late childhood. The presentation in patients with classic CAH can be fu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genitalia
A sex organ, also known as a reproductive organ, is a part of an organism that is involved in sexual reproduction. Sex organs constitute the primary sex characteristics of an organism. Sex organs are responsible for producing and transporting gametes, as well as facilitating fertilization and supporting the development and birth of offspring. Sex organs are found in many species of animals and plants, with their features varying depending on the species. Sex organs are typically differentiated into male and female types. In animals (including humans), the male sex organs include the testicles, epididymides, and penis; the female sex organs include the clitoris, ovaries, oviducts, and vagina. The testicle in the male and the ovary in the female are called the ''primary sex organs''. All other sex-related organs are known as ''secondary sex organs''. The outer parts are known as the genitals or external genitalia, visible at birth in both sexes, while the inner parts are refe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex Of Rearing
Sex assignment (also known as gender assignment) is the discernment of an infant's sex, typically made at birth based on an examination of the baby's external genitalia by a healthcare provider such as a midwife, nurse, or physician. In the vast majority of cases (99.95%), sex is assigned unambiguously at birth. However, in about 1 in 2000 births, the baby's genitalia may not clearly indicate male or female, necessitating additional diagnostic steps, and deferring sex assignment. In most countries the healthcare provider's determination, along with other details of the birth, is by law recorded on an official document and submitted to the government for later issuance of a birth certificate and for other legal purposes. The prevalence of intersex conditions, where a baby's sex characteristics do not conform strictly to typical definitions of male or female, ranges between 0.018% and 1.7%. While some intersex conditions result in genital ambiguity (approximately 0.02% to 0.0 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins Hospital
Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of Johns Hopkins School of Medicine in Baltimore, Maryland. Founded in 1889, Johns Hopkins Hospital and its school of medicine are considered to be the founding institutions of modern American medicine and the birthplace of numerous famed medical traditions, including rounds, residents, and house staff. Several medical specialties were founded at the hospital, including neurosurgery by Harvey Cushing and Walter Dandy, cardiac surgery by Alfred Blalock and Vivien Thomas, and child psychiatry by Leo Kanner. Johns Hopkins Children's Center, which serves infants, children, teens, and young adults aged 0–21, is attached to the hospital. Johns Hopkins Hospital is widely regarded as one of the world's greatest hospitals and medical institutions. For 21 consecutive years from 1991 to 2020, it was ranked as the best overall hospital in the United States by ''U.S. News & World Report''. In its 2019–20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hugh Hampton Young
Hugh Hampton Young (September 18, 1870 – August 23, 1945) was an American surgeon, urologist, and medical researcher. Biography Hugh H. Young was born in San Antonio, Texas, on September 18, 1870. He was the son of Confederate Brigadier General William Hugh Young and Frances (Kemper) Young. Young graduated from the University of Virginia in 1891 after acquiring BA, MA, and MD degrees in just four years. As of 1895 he began teaching at the Johns Hopkins Hospital and by 1897 he was the head of their urology department, at an age of just 27. The Brady Urological Institute, named after one of Young's patients, opened at Johns Hopkins in 1915. Young remained there for most of his life, until 1940. Among Young's contributions to the medical field are several inventions and discoveries, primarily relating to surgery. One such innovation was the "boomerang needle," a type of surgical needle designed for working with deep incisions. He also invented a device known as the Young punch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
