Herb-induced Liver Injury
Herb-induced liver injury (HILI) is a form of drug-induced liver injury caused by herbal medicines, typically herbal supplements or herb-based ethnomedicines. Prevalence Herbs are a common component of ethnomedicines and their potential hepatotoxicity is a concern for people taking such medicines or other herbal supplements. Use of such products is widespread within Ayurvedic medicine. Although injury from ayurvedic medicines has commonly been blamed on improper adulteration of drugs, a number of preparations can be harmful though direct effects purely because of their herbal ingredients. Implicated products * '' Tinospora cordifolia'' supplement usage is of concern as the constituent chemicals cause hepatitis. Advocates of ayurveda have attempted to blame adulteration for these effects but investigation has shown the toxicity to result directly from the medicine itself. Supplement use can lead to death or the need for a liver transplant. * Herbal supplements of '' Cullen c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Herbal Medicine
Herbal medicine (also called herbalism, phytomedicine or phytotherapy) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. Scientific evidence for the effectiveness of many herbal treatments remains limited, prompting ongoing regulatory evaluation and research into their safety and efficacy. Standards for purity or dosage are generally not provided. The scope of herbal medicine sometimes includes fungal and bee products, as well as minerals, shells and certain animal parts. Paraherbalism is the pseudoscientific use of plant or animal extracts as medicine, relying on unproven beliefs about the safety and effectiveness of minimally processed natural substances. Herbal medicine has been used since at least the Paleolithic era, with written records from ancient Sumer, Egypt, Greece, China, and India documenting its development and application over millennia. Modern herbal medicine is widely used globally—especially in Asia ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Turmeric
Turmeric (), or ''Curcuma longa'' (), is a flowering plant in the ginger family Zingiberaceae. It is a perennial, rhizomatous, herbaceous plant native to the Indian subcontinent and Southeast Asia that requires temperatures between and high annual rainfall to thrive. Plants are gathered each year for their rhizomes, some for propagation in the following season and some for consumption or dyeing. The rhizomes can be used fresh, but they are often boiled in water and dried, after which they are ground into a deep orange-yellow shelf-stable spice powder commonly used as a coloring and flavoring agent in many Asian cuisines, especially for curries ( curry powder). Turmeric powder has a warm, bitter, black pepper-like flavor and earthy, mustard-like aroma. Although long used in Ayurvedic medicine, there is no high-quality clinical evidence that consuming turmeric or the principal turmeric constituent, curcumin, is effective for treating any disease. Curcumin, a bright ye ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Biologically Based Therapies
Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and distribution of life. Central to biology are five fundamental themes: the cell (biology), cell as the basic unit of life, genes and heredity as the basis of inheritance, evolution as the driver of biological diversity, energy transformation for sustaining life processes, and the maintenance of internal stability (homeostasis). Biology examines life across multiple biological organisation, levels of organization, from molecules and cells to organisms, populations, and ecosystems. Subdisciplines include molecular biology, physiology, ecology, evolutionary biology, developmental biology, and systematics, among others. Each of these fields applies a range of methods to investigate biological phenomena, including scientific method, observation, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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History Of Botany
The history of botany examines the human effort to understand life on Earth by tracing the historical development of the discipline of botany—that part of natural science dealing with organisms traditionally treated as plants. Rudimentary botanical science began with empirically based plant lore passed from generation to generation in the oral traditions of Paleolithic hunter-gatherers. The first writings that show human curiosity about plants themselves, rather than the uses that could be made of them, appear in ancient Greece and ancient India. In Ancient Greece, the teachings of Aristotle's student Theophrastus at the Lyceum in ancient Athens in about 350 BC are considered the starting point for Western botany. In ancient India, the Vṛkṣāyurveda, attributed to Parashara, is also considered one of the earliest texts to describe various branches of botany. In Europe, botanical science was soon overshadowed by a medieval preoccupation with the medicinal properties of p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Botany
Botany, also called plant science, is the branch of natural science and biology studying plants, especially Plant anatomy, their anatomy, Plant taxonomy, taxonomy, and Plant ecology, ecology. A botanist or plant scientist is a scientist who specialises in this field. "Plant" and "botany" may be defined more narrowly to include only land plants and their study, which is also known as phytology. Phytologists or botanists (in the strict sense) study approximately 410,000 species of Embryophyte, land plants, including some 391,000 species of vascular plants (of which approximately 369,000 are flowering plants) and approximately 20,000 bryophytes. Botany originated as history of herbalism#Prehistory, prehistoric herbalism to identify and later cultivate plants that were edible, poisonous, and medicinal, making it one of the first endeavours of human investigation. Medieval physic gardens, often attached to Monastery, monasteries, contained plants possibly having medicinal benefit. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Herbalism
Herbal medicine (also called herbalism, phytomedicine or phytotherapy) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. Scientific evidence for the effectiveness of many herbal treatments remains limited, prompting ongoing regulatory evaluation and research into their safety and efficacy. Standards for purity or dosage are generally not provided. The scope of herbal medicine sometimes includes fungi, fungal and bee products, as well as Dietary mineral, minerals, Exoskeleton, shells and certain animal parts. Paraherbalism is the Pseudoscience, pseudoscientific use of plant or animal extracts as medicine, relying on unproven beliefs about the safety and effectiveness of minimally processed natural substances. Herbal medicine has been used since at least the Paleolithic era, with written records from ancient Sumer, Egypt, Greece, China, and India documenting its development and application over millennia. Modern herbal medici ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Liver
The liver is a major metabolic organ (anatomy), organ exclusively found in vertebrates, which performs many essential biological Function (biology), functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of various proteins and various other Biochemistry, biochemicals necessary for digestion and growth. In humans, it is located in the quadrants and regions of abdomen, right upper quadrant of the abdomen, below the thoracic diaphragm, diaphragm and mostly shielded by the lower right rib cage. Its other metabolic roles include carbohydrate metabolism, the production of a number of hormones, conversion and storage of nutrients such as glucose and glycogen, and the decomposition of red blood cells. Anatomical and medical terminology often use the prefix List of medical roots, suffixes and prefixes#H, ''hepat-'' from ἡπατο-, from the Greek language, Greek word for liver, such as hepatology, and hepatitis The liver is also an accessory digestive ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Injuries Of Abdomen, Lower Back, Lumbar Spine And Pelvis
Injury is physiology, physiological damage to the living tissue of any organism, whether Injury in humans, in humans, Injury in animals, in other animals, or Injury in plants, in plants. Injuries can be caused in many ways, including mechanically with penetrating trauma, penetration by sharp objects such as Tooth, teeth or blunt trauma, with blunt objects, by heat or cold, or by venoms and biotoxins. Injury prompts an Inflammation, inflammatory response in many taxa of animals; this prompts wound healing. In both plants and animals, substances are often released to help to occlude the wound, limiting loss of fluids and the entry of pathogens such as bacteria. Many organisms secrete antimicrobial chemicals which limit wound infection; in addition, animals have a variety of immune responses for the same purpose. Both plants and animals have regrowth mechanisms which may result in complete or partial healing over the injury. Cells too can Cell damage, repair damage to a certain de ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alternative Medicine
Alternative medicine refers to practices that aim to achieve the healing effects of conventional medicine, but that typically lack biological plausibility, testability, repeatability, or supporting evidence of effectiveness. Such practices are generally not part of evidence-based medicine. Unlike modern medicine, which employs the scientific method to test plausible therapies by way of Guidelines for human subject research, responsible and ethical clinical trials, producing repeatable evidence of either effect or of no effect, alternative therapies reside outside of mainstream medicine and do not originate from using the scientific method, but instead rely on testimonials, anecdotes, religion, tradition, superstition, belief in supernatural "Energy (esotericism), energies", pseudoscience, fallacy, errors in reasoning, propaganda, fraud, or other unscientific sources. Frequently used terms for relevant practices are New Age medicine, wikt:pseudo-medicine, pseudo-medicine, unortho ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Withania Somnifera
''Withania somnifera'', known commonly as ashwagandha, is an evergreen shrub in the Solanaceae family that is native to the Middle East and North Africa, other African regions, southern Europe, and Indian subcontinent. Several other species in the genus '' Withania'' are morphologically similar. Common names include Indian ginseng and winter cherry. ''W. somnifera'' is a short shrub 35–75 cm tall with tomentose branches, dull green elliptic leaves up to 10–12 cm long, small green bell-shaped flowers, and orange-red ripe fruit. The Latin species name ''somnifera'' means “ sleep-inducing,” while the name ashwagandha combines the Sanskrit words for “horse” and “smell,” referring to the root’s strong horse-like odor. It is cultivated mainly in dry regions of India and nearby countries like Nepal, Sri Lanka, China, and Yemen, preferring dry, stony soil with sun to partial shade, and is propagated from seeds in early spring or greenwood cuttings later. It is aff ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bioavailability
In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation. By definition, when a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered via routes other than intravenous, its bioavailability is lower due to intestinal epithelium absorption and first-pass metabolism. Thereby, mathematically, bioavailability equals the ratio of comparing the area under the plasma drug concentration curve versus time (AUC) for the extravascular formulation to the AUC for the intravascular formulation. AUC is used because AUC is proportional to the dose that has entered the systemic circulation. Bioavailability of a drug is an average value; to take population variability into account, deviation range is shown as ±. To ensure that the drug taker who has poor absorption is dosed appropriately, the bottom value of the deviation range is employed ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Comorbidities
In medicine, comorbidity refers to the simultaneous presence of two or more medical conditions in a patient; often co-occurring (that is, concomitant or concurrent) with a primary condition. It originates from the Latin term (meaning "sickness") prefixed with ("together") and suffixed with ''-ity'' (to indicate a state or condition). Comorbidity includes all additional ailments a patient may experience alongside their primary diagnosis, which can be either physiological or psychological in nature. In the context of mental health, comorbidity frequently refers to the concurrent existence of mental disorders, for example, the co-occurrence of depressive and anxiety disorders. The concept of multimorbidity is related to comorbidity but is different in its definition and approach, focusing on the presence of multiple diseases or conditions in a patient without the need to specify one as primary. Definition The term "comorbid" has three definitions: # to indicate a medical condit ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |