Fumarate Reductase (quinol)
Fumarate reductase (quinol) (, ''QFR,'' ''FRD'', ''menaquinol-fumarate oxidoreductase, quinol:fumarate reductase'') is an enzyme with List of enzymes, systematic name ''succinate:quinone oxidoreductase''. This enzyme catalysis, catalyzes the following chemical reaction: : fumarate + quinol \longrightarrow succinate + quinone Fumarate reductase (QFR) is a key enzyme induced by anaerobic growth of bacteria. By partaking in fumarate respiration, fumarate reductase performs the last step in the microbial anaerobic respiration. It is a membrane bound protein capable of Redox, oxidizing a quinone and passing the released electrons to an awaiting fumarate to be reduced. It is activated and synthesized under low oxygen conditions, when Cellular respiration, aerobic respiration cannot be performed and the cell must perform anaerobic respiration to grow. This reaction is opposite to the reaction that is catalyzed by the related complex II of the respiratory chain (succinate dehydrogenas ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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QFR Crystal
The Folk classification, in geology, is a technical descriptive classification of sedimentary rocks devised by Robert L. Folk, an influential sedimentary petrologist and Professor Emeritus at the University of Texas. Folk's sandstone (clastic) classification Folk's philosophy is that the name of a rock must convey as much information as possible without being a complete description. For this, he proposed five important properties of sandstones to use as defining characteristics. These five properties are: grain size, chemically precipitated cements, textural maturity, miscellaneous transported constituents, and clan designation. Folk's fivefold name must be in the following format: :(Grain size): (chemically precipitated cements) (textural maturity) (miscellaneous transported constituents) (clan designation) However, Folk stated that cements and miscellaneous transported constituents are optional categories as they are not always observed. The other three properties should always ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Crystallization
Crystallization is a process that leads to solids with highly organized Atom, atoms or Molecule, molecules, i.e. a crystal. The ordered nature of a crystalline solid can be contrasted with amorphous solids in which atoms or molecules lack regular organization. Crystallization can occur by various routes including Precipitation (chemistry), precipitation from solution, freezing of a liquid, or Deposition (phase transition), deposition from a gas. Attributes of the resulting crystal can depend largely on factors such as temperature, air pressure, cooling rate, or Solution (chemistry), solute concentration. Crystallization occurs in two major steps. The first is nucleation, the appearance of a crystalline phase from either a Supercooling, supercooled liquid or a supersaturation, supersaturated solvent. The second step is known as crystal growth, which is the increase in the size of particles and leads to a crystal state. An important feature of this step is that loose particles fo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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QFR Electron Transport Chain Labeled
The Folk classification, in geology, is a technical descriptive classification of sedimentary rocks devised by Robert L. Folk, an influential sedimentary petrologist and Professor Emeritus at the University of Texas. Folk's sandstone (clastic) classification Folk's philosophy is that the name of a rock must convey as much information as possible without being a complete description. For this, he proposed five important properties of sandstones to use as defining characteristics. These five properties are: grain size, chemically precipitated cements, textural maturity, miscellaneous transported constituents, and clan designation. Folk's fivefold name must be in the following format: :(Grain size): (chemically precipitated cements) (textural maturity) (miscellaneous transported constituents) (clan designation) However, Folk stated that cements and miscellaneous transported constituents are optional categories as they are not always observed. The other three properties should always ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Terminal Electron Acceptor
An electron acceptor is a chemical entity that accepts electrons transferred to it from another compound. Electron acceptors are oxidizing agents. The electron accepting power of an electron acceptor is measured by its redox potential. In the simplest case, electron acceptors are reduced by one electron. The process can alter the structure of the acceptor substantially. When the added electron is highly delocalized, the structural consequences of the reduction can be subtle. The central C-C distance in the electron acceptor tetracyanoethylene elongates from 135 to 143 pm upon acceptance of an electron. In the formation of some donor-acceptor complexes, less than one electron is transferred. TTF-TCNQ is a charge transfer complex. Biology In biology, a ''terminal electron acceptor'' often refers to either the last compound to receive an electron in an electron transport chain, such as oxygen during cellular respiration, or the last cofactor to receive an electron within the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hydride
In chemistry, a hydride is formally the anion of hydrogen (H−), a hydrogen ion with two electrons. In modern usage, this is typically only used for ionic bonds, but it is sometimes (and has been more frequently in the past) applied to all chemical compound, compounds containing covalent bond, covalently bound H atoms. In this broad and potentially archaic sense, water (H2O) is a hydride of oxygen, ammonia is a hydride of nitrogen, etc. In covalent compounds, it implies hydrogen is attached to a less electronegative chemical element, element. In such cases, the H centre has nucleophilic character, which contrasts with the protic character of acids. The hydride anion is very rarely observed. Almost all of the elements form Binary compounds of hydrogen, binary compounds with hydrogen, the exceptions being helium, He, neon, Ne, argon, Ar, krypton, Kr, promethium, Pm, osmium, Os, iridium, Ir, radon, Rn, francium, Fr, and radium, Ra. exotic atom#exotic molecules, Exotic molecules ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Active Site
In biology and biochemistry, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction. The active site consists of amino acid residues that form temporary bonds with the substrate, the ''binding site'', and residues that catalyse a reaction of that substrate, the ''catalytic site''. Although the active site occupies only ~10–20% of the volume of an enzyme, it is the most important part as it directly catalyzes the chemical reaction. It usually consists of three to four amino acids, while other amino acids within the protein are required to maintain the tertiary structure of the enzymes. Each active site is evolved to be optimised to bind a particular substrate and catalyse a particular reaction, resulting in high specificity. This specificity is determined by the arrangement of amino acids within the active site and the structure of the substrates. Sometimes enzymes also need to bind with some cofactors to fulfil their functio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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QFR Subunit B
The Folk classification, in geology, is a technical descriptive classification of sedimentary rocks devised by Robert L. Folk, an influential sedimentary petrologist and Professor Emeritus at the University of Texas. Folk's sandstone (clastic) classification Folk's philosophy is that the name of a rock must convey as much information as possible without being a complete description. For this, he proposed five important properties of sandstones to use as defining characteristics. These five properties are: grain size, chemically precipitated cements, textural maturity, miscellaneous transported constituents, and clan designation. Folk's fivefold name must be in the following format: :(Grain size): (chemically precipitated cements) (textural maturity) (miscellaneous transported constituents) (clan designation) However, Folk stated that cements and miscellaneous transported constituents are optional categories as they are not always observed. The other three properties should always ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cytoplasmic Membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the cytoplasm, interior of a Cell (biology), cell from the extracellular space, outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane Membrane fluidity, fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane membrane transport, controls the movement of substances in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Protein Complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains. Protein complexes are distinct from multidomain enzymes, in which multiple active site, catalytic domains are found in a single polypeptide chain. Protein complexes are a form of protein quaternary structure, quaternary structure. Proteins in a protein complex are linked by non-covalent interactions, non-covalent protein–protein interactions. These complexes are a cornerstone of many (if not most) biological processes. The cell is seen to be composed of modular supramolecular complexes, each of which performs an independent, discrete biological function. Through proximity, the speed and selectivity of binding interactions between Enzyme, enzymatic complex and substrates can be vastly improved, leading to higher cellular efficiency. Many of the techniques used to enter cells and isolate proteins are inherently disruptive to such large complexes, complicating the task of determining ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Catalysis
Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. The rate increase occurs because the catalyst allows the reaction to occur by an alternative mechanism which may be much faster than the noncatalyzed mechanism. However the noncatalyzed mechanism does remain possible, so that the total rate (catalyzed plus noncatalyzed) can only increase in the presence of the catalyst and never decrease. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usual ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alpha Helix
An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix). The alpha helix is the most common structural arrangement in the Protein secondary structure, secondary structure of proteins. It is also the most extreme type of local structure, and it is the local structure that is most easily predicted from a sequence of amino acids. The alpha helix has a right-handed helix conformation in which every backbone amino, N−H group hydrogen bonds to the backbone carbonyl, C=O group of the amino acid that is four residue (biochemistry), residues earlier in the protein sequence. Other names The alpha helix is also commonly called a: * Pauling–Corey–Branson α-helix (from the names of three scientists who described its structure) * 3.613-helix because there are 3.6 amino acids in one ring, with 13 atoms being involved in the ring formed by the hydrogen bond (starting with amidic hydrogen and ending with carbonyl oxygen) Discovery ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Heme
Heme (American English), or haem (Commonwealth English, both pronounced /Help:IPA/English, hi:m/ ), is a ring-shaped iron-containing molecule that commonly serves as a Ligand (biochemistry), ligand of various proteins, more notably as a Prosthetic group, component of hemoglobin, which is necessary to bind oxygen in the bloodstream. It is composed of four pyrrole rings with 2 Vinyl group, vinyl and 2 propionic acid side chains. Heme is biosynthesized in both the bone marrow and the liver. Heme plays a critical role in multiple different redox reactions in mammals, due to its ability to carry the oxygen molecule. Reactions include oxidative metabolism (cytochrome c oxidase, succinate dehydrogenase), xenobiotic detoxification via cytochrome P450 pathways (including Drug metabolism, metabolism of some drugs), gas sensing (Guanylate cyclase, guanyl cyclases, nitric oxide synthase), and microRNA processing (DGCR8). Heme is a coordination complex "consisting of an iron ion coordinated ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |