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Cetrimide
Cetrimide, or alkyltrimethylammonium bromide, is an antiseptic which is a mixture of three quaternary ammonium compounds: tetradonium bromide (TTAB or MITMAB), cetrimonium bromide (CTAB), and laurtrimonium bromide (DTAB or LTAB). It was first discovered and developed by ICI and introduced under the brand name ''Cetavlon''. It is used as a 1-3 % solution for cleaning roadside accident wounds. ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI sold the Savlon brand OTC to Johnson & Johnson Johnson & Johnson (J&J) is an American multinational pharmaceutical, biotechnology, and medical technologies corporation headquartered in New Brunswick, New Jersey, and publicly traded on the New York Stock Exchange. Its common stock is a c ... in May 1992. Cetrimide is used in various applications such as antiseptic agents, diagnostic test and analysis, topical formulations, and dental treatment. References Antiseptics Cationic surfacta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Savlon
Savlon is a brand of antibacterial personal care products with the active ingredients of cetrimide and chlorhexidine gluconate. Commonly sold as a cream, the product range also includes antiseptic sprays, sticking plasters and other antiseptic products. __TOC__ History The product name is derived from the original Imperial Chemical Industries (ICI) manufacturing site name of the Avlon Works at Avonmouth near Bristol, UK on the Severn Estuary. Savlon is sold in many countries with different manufacturing and licensing agreements. In 1992, Johnson & Johnson acquired the Savlon OTC brands from ICI. Since then, Johnson & Johnson manufactures and distributes Savlon products throughout Sub-Saharan Africa. In 2015, Johnson & Johnson sold Indian rights to the Savlon and Shower To Shower brands to ITC Limited. Also in 1992, ICI sold its Bangladesh rights to Savlon to ICI Bangladesh Manufacturers Limited, now ACI Limited. In Australia, Savlon was acquired by Reckitt Benckiser af ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Antiseptic
An antiseptic ( and ) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis, infection, or putrefaction. Antiseptics are generally distinguished from ''antibiotics'' by the latter's ability to safely destroy bacteria within the body, and from ''disinfectants'', which destroy microorganisms found on non-living objects. Antibacterials include antiseptics that have the proven ability to act against bacteria. Microbicides which destroy virus particles are called viricides or antivirals. Antifungals, also known as antimycotics, are pharmaceutical fungicides used to treat and prevent mycosis (fungal infection). Surgery Antiseptic practices evolved in the 19th century through multiple individuals. Ignaz Semmelweis showed already in 1847-1848 that hand washing prior to delivery reduced puerperal fever. Despite this, many hospitals continued to practice surgery in unsanitary conditions, with some surgeons taking pride in t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Quaternary Ammonium Compound
In organic chemistry, quaternary ammonium cations, also known as quats, are positively-charged polyatomic ions of the structure , where R is an alkyl group, an aryl group or organyl group. Unlike the ammonium, ammonium ion () and the primary, secondary, or tertiary ammonium cations, the Quaternary compound, quaternary ammonium cations are permanently charged, independent of the pH of their solution. Quaternary ammonium salts or quaternary ammonium compounds (called quaternary amines in oilfield parlance) are salt (chemistry), salts of quaternary ammonium cations. Polyquaternium, Polyquats are a variety of engineered polymer forms which provide multiple quat molecules within a larger molecule. Quats are used in consumer applications including as antimicrobials (such as detergents and disinfectants), fabric softeners, and hair conditioners. As an antimicrobial, they are able to inactivate viral envelope, enveloped viruses (such as SARS-CoV-2). Quats tend to be gentler on surfaces th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Cetrimonium Bromide
Cetrimonium bromide, also known with the abbreviation CTAB, is a quaternary ammonium surfactant with a condensed structural formula C16H33)N(CH3)3r. It is one of the components of the topical antiseptic cetrimide. The cetrimonium (hexadecyltrimethylammonium) cation is an effective antiseptic agent against bacteria and fungi. It is also one of the main components of some buffers for the extraction of DNA. It has been widely used in synthesis of gold nanoparticles (''e.g.'', spheres, rods, bipyramids), mesoporous silica nanoparticles (''e.g.'', MCM-41), and hair conditioning products. The closely related compounds cetrimonium chloride and cetrimonium stearate are also used as topical antiseptics and may be found in many household products such as shampoos and cosmetics. CTAB, due to its relatively high cost, is typically only used in select cosmetics. As with most surfactants, CTAB forms micelles in aqueous solutions. At 303 K (30 °C) it forms micelles with aggreg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Antiseptics
An antiseptic ( and ) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis, infection, or putrefaction. Antiseptics are generally distinguished from ''antibiotics'' by the latter's ability to safely destroy bacteria within the body, and from ''disinfectants'', which destroy microorganisms found on non-living objects. Antibacterials include antiseptics that have the proven ability to act against bacteria. Microbicides which destroy virus particles are called viricides or antivirals. Antifungals, also known as antimycotics, are pharmaceutical fungicides used to treat and prevent mycosis (fungal infection). Surgery Antiseptic practices evolved in the 19th century through multiple individuals. Ignaz Semmelweis showed already in 1847-1848 that hand washing prior to delivery reduced puerperal fever. Despite this, many hospitals continued to practice surgery in unsanitary conditions, with some surgeons taking pride in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Mixture
In chemistry, a mixture is a material made up of two or more different chemical substances which can be separated by physical method. It is an impure substance made up of 2 or more elements or compounds mechanically mixed together in any proportion. A mixture is the physical combination of two or more substances in which the identities are retained and are mixed in the form of solutions, suspensions or colloids. Mixtures are one product of mechanically blending or mixing chemical substances such as elements and compounds, without chemical bonding or other chemical change, so that each ingredient substance retains its own chemical properties and makeup. Despite the fact that there are no chemical changes to its constituents, the physical properties of a mixture, such as its melting point, may differ from those of the components. Some mixtures can be separated into their components by using physical (mechanical or thermal) means. Azeotropes are one kind of mixture that usual ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
European Pharmacopoeia
The ''European Pharmacopoeia'' (''Pharmacopoeia Europaea'', ''Ph. Eur.'') is a major regional pharmacopoeia which provides common quality standards throughout the pharmaceutical industry in Europe to control the quality of Pharmaceutical drug, medicines, and the substances used to Pharmaceutical manufacturing, manufacture them. It is a published collection of monographs which describe both the individual and general quality standards for ingredients, dosage forms, and methods of Pharmaceutical engineering, analysis for medicines. These standards apply to medicines for both Medicine, human and Veterinary medicine, veterinary use. Legal basis The ''European Pharmacopoeia'' has a Contract, legally binding character. It is used as an official reference to serve public health, and is part of the regulatory requirements for obtaining a Marketing Authorisation (MA) for a medicinal (human or veterinary) product. The quality standards of the European Pharmacopoeia apply throughout the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
The Stationery Office
The Stationery Office (TSO) is a British publishing company created in 1996 when the publishing arm of Her Majesty's Stationery Office was privatised. It is the official publisher and the distributor for legislation, command and house papers, select committee reports, ''Hansard'', and the London, Edinburgh and Belfast Gazettes, the UK government's three official journals of record. With more than 9,000 titles in print and digital formats published every year, it is one of the UK's largest publishers by volume. TSO provides services, consultancy, and infrastructure to deliver all aspects of the information lifecycle. TSO developed the website legislation.gov.uk with The National Archives, providing full access to the statute book as open data. The TSO OpenUp platform is a collection of integrated services available as software as a service (SaaS), with the aim of providing a scalable and resilient platform that allows organisations to store, query, and enrich their data. His ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Imperial Chemical Industries
Imperial Chemical Industries (ICI) was a British Chemical industry, chemical company. It was, for much of its history, the largest manufacturer in Britain. Its headquarters were at Millbank in London. ICI was listed on the London Stock Exchange and was a constituent of the FT 30 and later the FTSE 100 Index, FTSE 100 indices. ICI was formed in 1926 as a result of the merger of four of Britain's leading chemical companies. From the onset, it was involved in the production of various chemicals, explosives, fertilisers, insecticides, dyestuffs, non-ferrous metals, and paints; the firm soon become involved in plastics and a variety of speciality products, including food ingredients, polymers, electronic materials, fragrances and flavourings. During the Second World War, ICI's subsidiary Nobel Enterprises, ICI Nobel produced munitions for Britain's war effort; the wider company was also involved with Britain's nuclear weapons programme codenamed Tube Alloys. Throughout the 1940s and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Chlorhexidine
Chlorhexidine is a disinfectant and antiseptic which is used for skin disinfection before surgery and to disinfect surgical instruments. It is also used for cleaning wounds, preventing dental plaque, treating yeast infections of the mouth, and to keep urinary catheters from blocking. It is used as a liquid or a powder. It is commonly used in Ionic compound, salt form, either the gluconate or the acetate. Side effects may include skin irritation, Human tooth, tooth discoloration, and allergic reactions, although, apart from discoloration, the risk appears to be the same as that for povidone-iodine. Chlorhexidine rinse is also known to have a bitter metallic aftertaste. Rinsing with water is not recommended as it is known to increase the bitterness. It may cause eye problems if direct contact occurs. Use in pregnancy appears to be safe. Chlorhexidine may come mixed in ethanol, alcohol, water, or surfactant solution. It is effective against a range of microorganisms, but does not ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
