Brachyurin
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Brachyurin
Brachyurin (, ''Uca pugilator collagenolytic proteinase'', ''crab protease I'', ''crab protease II'') is an enzyme. This enzyme catalyses the Hydrolysis of proteins, with broad specificity for peptide bonds. Native collagen is cleaved about 75% of the length of the molecule from the N-terminus. This enzyme is isolated from hepatopancreas of the fiddler crab The fiddler crab or calling crab can be one of the hundred species of semiterrestrial marine crabs in the family Ocypodidae. These crabs are well known for their extreme sexual dimorphism, where the male crabs have a major claw significantly l ..., '' Uca pugilator''. References External links * {{Portal bar, Biology, border=no EC 3.4.21 ...
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Enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include Ribozyme, catalytic RNA molecules, also called ribozymes. They are sometimes descr ...
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Catalysis
Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. The rate increase occurs because the catalyst allows the reaction to occur by an alternative mechanism which may be much faster than the noncatalyzed mechanism. However the noncatalyzed mechanism does remain possible, so that the total rate (catalyzed plus noncatalyzed) can only increase in the presence of the catalyst and never decrease. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usual ...
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Hydrolysis
Hydrolysis (; ) is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution reaction, substitution, elimination reaction, elimination, and solvation reactions in which water is the nucleophile. Biological hydrolysis is the cleavage of Biomolecule, biomolecules where a water molecule is consumed to effect the separation of a larger molecule into component parts. When a carbohydrate is broken into its component sugar molecules by hydrolysis (e.g., sucrose being broken down into glucose and fructose), this is recognized as saccharification. Hydrolysis reactions can be the reverse of a condensation reaction in which two molecules join into a larger one and eject a water molecule. Thus hydrolysis adds water to break down, whereas condensation builds up by removing water. Types Usually hydrolysis is a chemical process in which a molecule of water is added to a substance. Sometimes this addition causes both the su ...
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Peptide Bond
In organic chemistry, a peptide bond is an amide type of covalent chemical bond linking two consecutive alpha-amino acids from C1 (carbon number one) of one alpha-amino acid and N2 (nitrogen number two) of another, along a peptide or protein chain. It can also be called a eupeptide bond to distinguish it from an isopeptide bond, which is another type of amide bond between two amino acids. Synthesis When two amino acids form a '' dipeptide'' through a ''peptide bond'', it is a type of condensation reaction. In this kind of condensation, two amino acids approach each other, with the non-side chain (C1) carboxylic acid moiety of one coming near the non-side chain (N2) amino moiety of the other. One loses a hydrogen and oxygen from its carboxyl group (COOH) and the other loses a hydrogen from its amino group (NH2). This reaction produces a molecule of water (H2O) and two amino acids joined by a peptide bond (−CO−NH−). The two joined amino acids are called a dipeptide. The ...
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Collagen
Collagen () is the main structural protein in the extracellular matrix of the connective tissues of many animals. It is the most abundant protein in mammals, making up 25% to 35% of protein content. Amino acids are bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in cartilage, bones, tendons, ligaments, and skin. Vitamin C is vital for collagen synthesis. Depending on the degree of biomineralization, mineralization, collagen tissues may be rigid (bone) or compliant (tendon) or have a gradient from rigid to compliant (cartilage). Collagen is also abundant in corneas, blood vessels, the Gut (anatomy), gut, intervertebral discs, and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and 6% by weight of skeletal muscle. The fibroblast is the most common cell creating collagen in animals. Gelatin, which is used in food and industry, is collagen t ...
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide. Within a peptide, the amine group is bonded to the carboxylic group of another amino acid, making it a chain. That leaves a free carboxylic group at one end of the peptide, called the C-terminus, and a free amine group on the other end called the N-terminus. By convention, peptide sequences are written N-terminus to C-terminus, left to right (in LTR writing systems). This correlates the translation direction to the text direction, because when a protein is translated from messenger RNA, it is created from the N-terminus to the C-terminus, as amino acids are added to the carboxyl end of the protein. Chemistry Each amino acid has an amine group and a carboxylic group. Amino acids link to one another by peptide bonds which form through a dehydration reaction that ...
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Hepatopancreas
The hepatopancreas, digestive gland or midgut gland is an organ of the digestive tract of arthropods and molluscs. It provides the functions which in mammals are provided separately by the liver and pancreas, including the production of digestive enzymes, and absorption of digested food. Arthropods Arthropods, especially detritivores in the Order Isopoda, Suborder Oniscidea (woodlice), have been shown to be able to store heavy metals in their hepatopancreas. This could lead to bioaccumulation through the food chain and implications for food web destruction, if the accumulation gets high enough in polluted areas; for example, high metal concentrations are seen in spiders of the genus '' Dysdera'' which feed on woodlice, including their hepatopancreas, the major metal storage organ of isopods in polluted sites. Molluscs The hepatopancreas is a centre for lipid metabolism and for storage of lipids in gastropods Gastropods (), commonly known as slugs and snails, belong to a ...
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Fiddler Crab
The fiddler crab or calling crab can be one of the hundred species of semiterrestrial marine crabs in the family Ocypodidae. These crabs are well known for their extreme sexual dimorphism, where the male crabs have a major claw significantly larger than their minor claw, whilst females claws are both the same size. The name fiddler crab comes from the appearance of their small and large claw together, looking similar to a fiddle. A smaller number of ghost crab and mangrove crab species are also found in the family Ocypodidae. This entire group is composed of small crabs, the largest being ''Afruca tangeri'' which is slightly over two inches (5 cm) across. Fiddler crabs are found along sea beaches and brackish intertidal mud flats, lagoons, swamps, and various other types of brackish or salt-water wetlands. Whilst fiddler crabs are currently split into two subfamilies of Gelasiminae and Ucinae, there is still phylogenetic and taxonomical debate as to whether the movement ...
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Uca Pugilator
''Leptuca pugilator'', the sand fiddler crab, Atlantic sand fiddler crab, or Calico fiddler, is a species of fiddler crab that is found from Massachusetts to the Gulf of Mexico. It lives in burrows in coastal and estuarine mud-flats, and can be extremely abundant. It can be differentiated from the morphologically similar ''Minuca pugnax'' and ''Minuca minax'' by the smoothness of the inside of its claws. One claw is larger than the other, and can be much larger than the crab's body, at up to long. ''Leptuca pugilator'' was formerly in the genus '' Uca'', but in 2016 it became a member of the genus ''Leptuca'', a former subgenus of ''Uca''. Description The carapace is square in shape, tapering slightly to the rear; it can reach a width of , but is typically up to wide and long. The space between the eyes is much shorter than the eyestalk. The males have one extremely enlarged chela (claw), which they use to claim their territory and fight with other males. The claw can be muc ...
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