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Bone Cancer
A bone tumor is an neoplastic, abnormal growth of tissue in bone, traditionally classified as benign, noncancerous (benign) or malignant, cancerous (malignant). Cancerous bone tumors usually originate from a cancer in another part of the body such as from Lung cancer, lung, Breast cancer, breast, Thyroid cancer, thyroid, kidney cancer, kidney and Prostate cancer, prostate. There may be a lump, pain, or focal neurologic signs, neurological signs from pressure. A bone tumor might present with a pathologic fracture. Other symptoms may include fatigue (medical), fatigue, fever, weight loss, anemia and nausea. Sometimes there are no symptoms and the tumour is found when investigating another problem. Diagnosis is generally by Projectional radiography, X-ray and other Radiography, radiological tests such as CT scan, MRI, Positron emission tomography, PET scan and bone scintigraphy. Blood tests might include a complete blood count, inflammatory markers, Gel electrophoresis of proteins ...
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Non-ossifying Fibroma
A non-ossifying fibroma (NOF) is a benign bone tumor of the osteoclastic, Giant-cell tumor of bone, giant cell-rich tumor type. It generally occurs in the metaphysis of long bones in children and adolescents. Typically, there are no symptoms unless there is a fracture. It can occur as part of a syndrome such as when multiple non-ossifying fibromas occur in neurofibromatosis, or Jaffe–Campanacci syndrome in combination with cafe-au-lait spots, Intellectual disability, intellectual disabilities, hypogonadism, eye and cardiovascular abnormalities. Diagnosis is by X-ray or MRI, usually when investigating a person for something else. Medical imaging typically shows a well defined radiolucent lesion, with a distinct multilocular appearance, sometimes looking like bubbles. It is usually around 1–2 cm in size, but be as large as 7 cm. They consist of foci consist of collagen rich connective tissue, fibroblasts, histiocytes and osteoclasts. Usually no treatment is required. ...
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