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Antivenom
Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection. Side effects may be severe. They include serum sickness, shortness of breath, and allergic reactions including anaphylaxis. Antivenom is traditionally made by collecting venom from the relevant animal and injecting small amounts of it into a domestic animal. The antibodies that form are then collected from the domestic animal's blood and purified. Versions are available for spider bites, snake bites, fish stings, and scorpion stings. Due to the high cost of producing antibody-based antivenoms and their short shelf lives when not refrigerated, alternative methods of production of antiven ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Redback Spider
The redback spider (''Latrodectus hasselti''), also known as the Australian black widow, is a species of highly venomous spider believed to originate in Australia, but which is now found in Southeast Asia and New Zealand. It has also been found in packing crates in the United States with colonies elsewhere outside Australia. It is a member of the Cosmopolitan distribution, cosmopolitan genus ''Latrodectus'', the widow spiders. The adult female is easily recognised by her spherical black body with a prominent red stripe on the upper side of her abdomen and an hourglass-shaped red/orange streak on the underside. Females usually have a body length of about , while the male is much smaller, being only long. Mainly nocturnal, the female redback lives in an untidy web in a warm sheltered location, commonly near or inside human residences. It preys on insects, spiders and small vertebrates that become ensnared in its web. It kills its prey by injecting a complex venom through its t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Snake Antivenom
Snake antivenom is a medication made up of antibodies used to treat snake bites by venomous snakes. It is a type of antivenom. It is a biological product that typically consists of venom neutralizing antibodies derived from a host animal, such as a horse or sheep. The host animal is hyperimmunized to one or more snake venoms, a process which creates an immunological response that produces large numbers of neutralizing antibodies against various components (toxins) of the venom. The antibodies are then collected from the host animal, and further processed into snake antivenom for the treatment of envenomation. It is on the World Health Organization's List of Essential Medicines. Production Antivenoms are typically produced using a donor animal, such as a horse or sheep. The donor animal is hyperimmunized with non-lethal doses of one or more venoms to produce a neutralizing antibody response. Then, at certain intervals, the blood from the donor animal is collected and neut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spider Bites
A spider bite, also known as arachnidism, is an injury resulting from the bite of a spider. The effects of most bites are not serious. Most bites result in mild symptoms around the area of the bite. Rarely they may produce a necrotic skin wound or severe pain. Most spiders do not cause bites that are of importance. For a bite to be significant, substantial envenomation is required. Bites from the widow spiders involve a neurotoxic venom which produces a condition known as latrodectism. Symptoms may include pain which may be at the bite or involve the chest and abdomen, sweating, muscle cramps and vomiting among others. Bites from the recluse spiders cause the condition loxoscelism, in which local necrosis of the surrounding skin and widespread breakdown of red blood cells may occur. Headaches, vomiting and a mild fever may also occur. Other spiders that can cause significant bites include the Australian funnel-web spider and South American wandering spider. Efforts to p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Snake Bites
A snakebite is an injury caused by the bite of a snake, especially a venomous snake. A common sign of a bite from a venomous snake is the presence of two puncture wounds from the animal's fangs. Sometimes venom injection from the bite may occur. This may result in redness, swelling, and severe pain at the area, which may take up to an hour to appear. Vomiting, blurred vision, tingling of the limbs, and sweating may result. Most bites are on the hands, arms, or legs. Fear following a bite is common with symptoms of a racing heart and feeling faint. The venom may cause bleeding, kidney failure, a severe allergic reaction, tissue death around the bite, or breathing problems. Bites may result in the loss of a limb or other chronic problems or even death. The outcome depends on the type of snake, the area of the body bitten, the amount of snake venom injected, the general health of the person bitten, and whether or not anti-venom serum has been administered by a doctor in a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stonefish
''Synanceia'' is a genus of Actinopterygii, ray-finned fish belonging to the subfamily Synanceiinae, the stonefish, which is Taxonomy (biology), classified within the Family (biology), family Scorpaenidae, the scorpionfish and relatives. Stonefish are the most venomous fish known; stings can be fatal to humans. They are found in the coastal regions of the Indo-Pacific. They are sometimes confused with the Bullrout, freshwater lionfish. Taxonomy ''Synanceia'' was first described as a genus in 1801 by the German naturalists Marcus Elieser Bloch and Johann Gottlob Theaenus Schneider with ''Scorpaena horrida'', which had been Species description, described by Carl Linnaeus in 1766 from Ambon Island (Indonesia), as its type species. The genus ''Synanceia'' is classified within the Tribe (biology), tribe Synanceiini which is one of three tribes in the subfamily Synanceeinae within the family Scorpaenidae. Despite this, other authorities regard Synanceiidae as a valid family and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coral Snake
Coral snakes are a large group of elapid snakes that can be divided into two distinct groups, the Old World coral snakes and New World coral snakes. There are 27 species of Old World coral snakes, in three genera ('' Calliophis'', '' Hemibungarus'', and '' Sinomicrurus''), and 83 recognized species of New World coral snakes, in two genera ('' Micruroides'' and '' Micrurus''). Genetic studies have found that the most basal lineages have origins in Asia, suggesting that the group originated in the Old World. While new world species of both genera are venomous, their bites are seldom lethal; only two confirmed fatalities have been documented in the past 100 years from the genus ''Micrurus''. Meanwhile, snakes of the genus ''Micruroides'' have never caused a medically significant bite. North American coloration patterns Experts now recognize that certain coloration patterns and common mnemonics—such as the phrase “Red against yellow, deadly fellow; red against black, friendly J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CroFab
Crotalidae polyvalent immune Fab (ovine), sold under the brandname CroFab, is a snake antivenin, indicated for North American crotalid (rattlesnake, copperhead and cottonmouth/water moccasin) snake envenomation. CroFab is composed of several monovalent Fab (fragment antigen-binding) proteins derived from the blood of sheep immunized with one of four snake venoms: ''Crotalus atrox'' ( western diamondback rattlesnake), ''Crotalus adamanteus'' ( Eastern diamondback rattlesnake), '' Crotalus scutulatus'' (Mojave rattlesnake), or '' Agkistrodon piscivorus'' (cottonmouth or water moccasin). Each monospecific antivenin is purified from sheep serum, digested with the enzyme papain, and purified further, resulting in specific Fab fragments. The resulting four different Fab preparations are mixed to formulate the final product. Background The production technology was invented by Drs. John Sullivan and Findlay Russell, developed clinically via multicenter clinical trials in the Un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rattlesnake
Rattlesnakes are venomous snakes that form the genus, genera ''Crotalus'' and ''Sistrurus'' of the subfamily Crotalinae (the pit vipers). All rattlesnakes are vipers. Rattlesnakes are predators that live in a wide array of habitats, hunting small animals such as birds and rodents. Rattlesnakes receive their name from the #Rattle, rattle located at the end of their tails, which makes a loud rattling noise when tail vibration, vibrated that deters predators. Rattlesnakes are the leading contributor to snakebite injuries in North America, but rarely bite unless provoked or threatened; if treated promptly, the bites are seldom fatal. The 36 known List of rattlesnake species and subspecies, species of rattlesnakes have between 65 and 70 subspecies, all native to the Americas, ranging from central Argentina to southern Canada. The largest rattlesnake, the Eastern diamondback rattlesnake, eastern diamondback, can measure up to in length. Rattlesnakes are preyed upon by hawks, wease ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
WHO Model List Of Essential Medicines
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. The list is frequently used by countries to help develop their own local lists of essential medicines. , more than 155 countries have created national lists of essential medicines based on the World Health Organization's model list. This includes both Developed country, developed and Developing country, developing countries. The list is divided into core items and complementary items. The core items are deemed to be the most cost-effective options for key health problems and are usable with little additional health care resources. The complementary items either require additional infrastructure such as specially trained health care providers or diagnostic equipment or have a lower cost–benefit ratio. About 25% of items are in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agkistrodon Contortrix
The eastern copperhead (''Agkistrodon contortrix''), also known simply as the copperhead, is a widespread species of venomous snake, a pit viper, endemic to eastern North America; it is a member of the subfamily Crotalinae in the Family (biology), family Viperidae. The eastern copperhead has distinctive, dark brown, hourglass-shaped markings, overlaid on a light reddish brown or brown/gray background. The body type is heavy, rather than slender. Neonates are born with green or yellow tail tips, which progress to a darker brown or black within one year. Adults grow to a typical length (including tail) of . In most of North America, the eastern copperhead favors Deciduous, deciduous forest and mixed woodlands. It may occupy rock outcroppings and ledges, but is also found in low-lying, swampy regions. During the winter, it hibernates in dens or limestone crevices, often together with timber rattlesnakes and black rat snakes. The eastern copperhead is known to feed on a wide variety ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fish Stings
A fish sting is an injury which may include envenomation and mechanical trauma. There are a number of species of venomous fish including the stonefish. Stonefish sting lethality in man has been scarcely documented since the middle of the 20th century. We report three clinical cases, including one fatality, emphasizing the cardiovascular toxicity of the Synanceia verrucosa venom, and its potentially lethal effects. All clinical data have been recently collected in New Caledonia and French Polynesia. Due to the medical significance of the venom, there is a notable lack of research on stonefish ichthyocrinotoxins. Future research should investigate the toxins role in predator defence, parasite prevention, and mitigating epibiosis. Further inquiry into stonefish toxins would expand ecological insights and may reveal therapeutic and industrial potential Antivenom is available for stonefish stings. Weeverfish sting Weeverfish are colorful marine animals which grow up to 1.5 feet i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunogen
An immunogen is any substance that generates B-cell (humoral/antibody) and/or T-cell (cellular) adaptive immune responses upon exposure to a host organism. Immunogens that generate antibodies are called antigens ("antibody-generating"). Immunogens that generate antibodies are directly bound by host antibodies and lead to the selective expansion of antigen-specific B-cells. Immunogens that generate T-cells are indirectly bound by host T-cells after processing and presentation by host antigen-presenting cells. An immunogen can be defined as a complete antigen which is composed of the macromolecular carrier and epitopes (determinants) that can induce immune response. An explicit example is a hapten. Haptens are low-molecular-weight compounds that may be bound by antibodies, but cannot elicit an immune response. Consequently, the haptens themselves are nonimmunogenic and they cannot evoke an immune response until they bind with a larger carrier immunogenic molecule. The hapten-car ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
