|
Abaucin
Abaucin (RS-102895, MLJS-21001) is a spirocycle containing substituted phenethylamine that has been reported to show useful activity as a narrow-spectrum antibiotic. There is evidence that it is effective against ''Acinetobacter baumannii'', which is one of three bacterial species identified by the World Health Organization as a "critical threat" to humanity. Notably, abaucin was developed with assistance from artificial intelligence by a team led by the MIT Jameel Clinic's faculty lead for life sciences, James Collins (bioengineer), James J. Collins, and McMaster University, McMaster's Jonathan Stokes. Its mode of action involves inhibiting lipoprotein transport. The compound had previously been reported as an antagonist of the chemokine receptor CCR2, but the molecule's antibiotic activity was not discovered until 2023. A The New York Times, New York Times opinion piece by Peter Coy for Thanksgiving (United States), Thanksgiving listed abaucin among scientific discoveries to be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
MIT Jameel Clinic
The MIT Abdul Latif Jameel Clinic for Machine Learning in Health (commonly, MIT Jameel Clinic; previously, J-Clinic) is a research center at the Massachusetts Institute of Technology (MIT) in the field of artificial intelligence (AI) and health sciences, including disease detection, drug discovery, and the development of medical devices. The MIT Jameel Clinic also supports the commercialization of solutions through grant funding, and has partnered with pharmaceutical companies, like Takeda and Sanofi, and philanthropies, like Community Jameel and Wellcome Trust, to forge collaborations between research and development functions and MIT researchers. Co-founded in 2018 by MIT and Community Jameel, the MIT Jameel Clinic is housed in the MIT Schwarzman College of Computing. The mission of the Jameel Clinic is to "revolutionize the prevention, detection, and treatment of disease", and it describes itself as "the epicenter of AI and healthcare at MIT". The MIT Jameel Clinic is known f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |