Yezo Virus
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Yezo Virus
Yezo virus (''Orthonairovirus yezoense'') is a species of virus in the genus ''Orthonairovirus'', discovered 2021 in Japan, circulating in mammals and ticks, causing a mild febrile illness in humans. Virology Yezo virus is classified into the genus ''Orthonairovirus'' and is phylogenetically grouped with Sulina virus. Natural reservoir As of 2021, Yezo virus was found in wild deer, raccoons, and ticks from Hokkaido, the northernmost island in Japan. They were not found in Hokkaido raccoon dogs (''Nyctereutes procyonoides albus'') or rodents (''Myodes rufocanus bedfordiae'' and ''Apodemus speciosus''). Among the three major tick species in Hokkaido ('' Haemaphysalis megaspinosa'', '' Ixodes ovatus'', and ''Ixodes persulcatus'') Yezo virus was most commonly detected in H. megaspinosa. It is suspected to circulate in Ixodes ticks as well, so the geographical range may extend much further into Asia and Europe. In 2024, Yezo virus was also found in 0.5% of ''Ixodes persulcatus'' t ...
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Orthonairovirus
''Orthonairovirus'' is a genus of viruses in the family '' Nairoviridae'' of the order '' Hareavirales'' which includes viruses with circular, negative-sense single stranded RNA. The name is derived from the Nairobi sheep disease which affects the gastrointestinal tracts of sheep and goats. All viruses in this genus are tick-borne viruses with human or other vertebrate hosts. Structure The virions for viruses in this genus have a spherical shape. They range in size from about 80–120 nm in diameter, with 50% of their weight attributed to proteins and 20–30% of their weight attributed to lipids. The ribonucleocapsid is filamentous, having a length of about 200-300 nm and a width of about 2–2.5 nm. These nucleocapsids are surrounded by a single envelope that has projections made of glycoproteins protruding from its surface. These projections evenly cover the surface of the virion, and are about 5–10 nm long. They aid in attachment to the host r ...
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Sulina Virus
Sulina () is a town and free port in Tulcea County, Northern Dobruja, Romania, at the mouth of the Sulina branch of the Danube. It is the easternmost point of Romania. History During the mid-Byzantine period, Sulina was a small cove, and in the 14th century, a Genoese port inhabited by a handful of sailors, pirates and fishermen. In the 18th century, the Ottomans built a lighthouse there in order to facilitate communication between Constantinople (Istanbul) and the Danubian Principalities, the main breadbaskets for the Ottoman capital. Thanks to the signing of the Treaty of Adrianoupolis (Edirne) on September 2, 1829, that unfettered the Danube grain trade, Sulina, by then under Russian control, became an important port. Great sailing boats could not sail fully loaded to Brăila and Galați, which were the main export centers of Wallachia and Moldavia, because of the shallow waters of the river; therefore, they had to transship at least part of their cargoes to smaller riverbo ...
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Hokkaido
is the list of islands of Japan by area, second-largest island of Japan and comprises the largest and northernmost prefectures of Japan, prefecture, making up its own list of regions of Japan, region. The Tsugaru Strait separates Hokkaidō from Honshu; the two islands are connected by railway via the Seikan Tunnel. The largest city on Hokkaido is its capital, Sapporo, which is also its only cities designated by government ordinance of Japan, ordinance-designated city. Sakhalin lies about to the north of Hokkaidō, and to the east and northeast are the Kuril Islands, which are administered by Russia, though the four most southerly are Kuril Islands dispute, claimed by Japan. The position of the island on the northern end of the archipelago results in a colder climate, with the island seeing significant snowfall each winter. Despite the harsher climate, it serves as an agricultural breadbasket for many crops. Hokkaido was formerly known as ''Ezo'', ''Yezo'', ''Yeso'', or ''Yes ...
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Haemaphysalis Megaspinosa
''Haemaphysalis'' is a genus of ticks, containing these species: *'' Haemaphysalis aborensis'' Warburton, 1913 *'' Haemaphysalis aciculifer'' Warburton, 1913 *'' Haemaphysalis aculeata'' Lavarra, 1904 *'' Haemaphysalis adleri'' Feldman-Muhsam, 1951 *'' Haemaphysalis anomala'' Warburton, 1913 *'' Haemaphysalis anomaloceraea'' Teng & Cui, 1984 *'' Haemaphysalis anoplos'' Hoogstraal, Uilenberg & Klein, 1967 *'' Haemaphysalis aponommoides'' Warburton, 1913 *'' Haemaphysalis asiatica'' (Supino, 1897) *'' Haemaphysalis atheruri'' Hoogstraal, Trapido & Kohls, 1965 *'' Haemaphysalis bancrofti'' Nuttall & Warburton, 1915 *'' Haemaphysalis bandicota'' Hoogstraal & Kohls, 1965 *''Haemaphysalis bartelsi'' Schulze, 1938 *''Haemaphysalis bequaerti'' Hoogstraal, 1956 *'' Haemaphysalis birmaniae'' Supino, 1897 *'' Haemaphysalis bispinosa'' Neumann, 1897 *'' Haemaphysalis bochkovi'' Apanaskevich & Tomlinson, 2019Dmitry Apanaskevich and Jackson A. Tomlinson. 2019. Description of four new species of ...
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Ixodes Ovatus
''Ixodes'' is a genus of hard-bodied ticks (family Ixodidae). It includes important disease vectors of animals and humans (tick-borne disease), and some species (notably ''Ixodes holocyclus'') inject toxins that can cause paralysis. Some ticks in this genus may transmit the pathogenic bacterium ''Borrelia burgdorferi'' responsible for causing Lyme disease. Additional organisms that may be transmitted by ''Ixodes'' are parasites from the genus ''Babesia'', which cause babesiosis, and bacteria from the related genus ''Anaplasma'', which cause anaplasmosis. Species These species are recognised within the genus ''Ixodes'': *''Ixodes abrocomae'' Lahille, 1916 *''Ixodes acer'' Apanaskevich & Schenk, 2020 *''Ixodes acuminatus'' Neumann, 1901 *''Ixodes acutitarsus'' (Karsch, 1880) *''Ixodes affinis'' Neumann, 1899 *''Ixodes albignaci'' Uilenberg & Hoogstraal, 1969 *''Ixodes alluaudi'' Neumann, 1913 *'' Ixodes amarali'' Fonseca, 1935 *'' Ixodes amersoni'' Kohls, 1966 *'' Ixodes anat ...
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Ixodes Persulcatus
''Ixodes persulcatus'', the taiga tick, is a species of hard-bodied tick distributed from Europe through central and northern Asia to China and Japan. The sexual dimorphism of the species is marked, the male being much smaller than the female. Hosts include wild and domestic ungulates, man, dog, rabbit, and other small mammals, including the dormouse, Amur hedgehog, and occasionally birds. Disease transmission ''Ixodes persulcatus'' ticks transmit Lyme disease, relapsing fever (''Borrelia miyamotoi''), babesiosis, and Siberian (TBEV-Sib) and Far Eastern (TBEV-FE) tick-borne encephalitis, and probably human granulocytic anaplasmosis as well. A recent study of the northernmost tick-borne encephalitis focus in Simo, Finnish Lapland, found ''I. persulcatus'' ticks in scattered foci along the western coast, including the Kokkola archipelago and Närpes Närpes (Finland Swedish: ; ) is a town in Finland, located on the west coast of the country. Närpes is situated in Ostroboth ...
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Ixodes
''Ixodes'' is a genus of hard-bodied ticks (family Ixodidae). It includes important disease vectors of animals and humans ( tick-borne disease), and some species (notably '' Ixodes holocyclus'') inject toxins that can cause paralysis. Some ticks in this genus may transmit the pathogenic bacterium '' Borrelia burgdorferi'' responsible for causing Lyme disease. Additional organisms that may be transmitted by ''Ixodes'' are parasites from the genus '' Babesia'', which cause babesiosis, and bacteria from the related genus '' Anaplasma'', which cause anaplasmosis. Species These species are recognised within the genus ''Ixodes'': *'' Ixodes abrocomae'' Lahille, 1916 *'' Ixodes acer'' Apanaskevich & Schenk, 2020 *'' Ixodes acuminatus'' Neumann, 1901 *'' Ixodes acutitarsus'' (Karsch, 1880) *'' Ixodes affinis'' Neumann, 1899 *'' Ixodes albignaci'' Uilenberg & Hoogstraal, 1969 *'' Ixodes alluaudi'' Neumann, 1913 *'' Ixodes amarali'' Fonseca, 1935 *'' Ixodes amersoni'' Kohls, 1966 ...
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Heilongjiang
Heilongjiang is a province in northeast China. It is the northernmost and easternmost province of the country and contains China's northernmost point (in Mohe City along the Amur) and easternmost point (at the confluence of the Amur and Ussuri rivers). The province is bordered by Jilin to the south and Inner Mongolia to the west. It also shares a border with Russia ( Amur Oblast, Jewish Autonomous Oblast, Khabarovsk Krai, Primorsky Krai and Zabaykalsky Krai) to the north and east. The capital and the largest city of the province is Harbin. Among Chinese provincial-level administrative divisions, Heilongjiang is the sixth-largest by total area, the 20th-most populous, and the second-poorest by GDP per capita after only Gansu province. The province takes its name from the Amur river which marks the border between the People's Republic of China and Russia. Heilongjiang has significant agricultural production, and raw materials, such as timber, oil, and coal. Etymology ...
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Jilin
) , image_skyline = Changbaishan Tianchi from western rim.jpg , image_alt = , image_caption = View of Heaven Lake , image_map = Jilin in China (+all claims hatched).svg , mapsize = 275px , map_alt = Map showing the location of Jilin Province , map_caption = Map showing the location of Jilin Province , coordinates = , subdivision_type = Country , subdivision_name = China , named_for = from ''girin ula'', a Manchu language, Manchu phrase meaning "along the river" , seat_type = Capital , seat = , seat1_type = , seat1 = , parts_type = Divisions , parts_style = para , p1 = 9 Prefectures of China, prefectures , p2 = 60 Counties of China, counties , p3 = 1006 Townships of China, townships , government_type = Provinces of China, Province , governing_body = Jilin Provinci ...
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Thrombocytopenia
In hematology, thrombocytopenia is a condition characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood. Low levels of platelets in turn may lead to prolonged or excessive bleeding. It is the most common coagulation disorder among intensive care units, intensive care patients and is seen in a fifth of medical patients and a third of surgical patients. A normal human platelet count ranges from 150,000 to 450,000 platelets/microliter (μL) of blood. Values outside this range do not necessarily indicate disease. One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. Thrombocytopenia can be contrasted with the conditions associated with an abnormally ''high'' level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). Signs and symptoms Thrombocytopenia usually asymptomatic, has no symptoms and is picked up on a routine comp ...
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Leukopenia
Leukopenia () is a decrease in the number of white blood cells (leukocytes). It places individuals at increased risk of infection as white blood cells are the body's primary defense against infections. Signs and symptoms Symptoms may include: * skin or mouth ulcers * sore throat * cough * difficulty in breathing * light-headedness * fever * chills * body aches Leukopenia vs. neutropenia Neutropenia, a subtype of leukopenia, refers to a decrease in the number of circulating neutrophil granulocytes, the most abundant white blood cells. The terms ''leukopenia'' and ''neutropenia'' may occasionally be used interchangeably, as the neutrophil count is the most important indicator of infection risk. Agranulocytosis is an acute form of neutropenia. Causes Medical conditions Low white cell count may be due to acute viral infections, such as a cold or influenza. It has been associated with chemotherapy, radiation therapy, myelofibrosis, aplastic anemia (failure of white cell, red ...
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Lymphocytopenia
Lymphocytopenia is the condition of having an abnormally low level of lymphocytes in the blood. Lymphocytes are a white blood cell with important functions in the immune system. It is also called lymphopenia. The opposite is lymphocytosis, which refers to an excessive level of lymphocytes. Lymphocytopenia may be present as part of a pancytopenia, when the total numbers of all types of blood cells are reduced. Classification In some cases, lymphocytopenia can be further classified according to which kind of lymphocytes are reduced. If all three kinds of lymphocytes are suppressed, then the term is used without further qualification. * In T lymphocytopenia, there are too few T lymphocytes, but normal numbers of other lymphocytes. It causes, and manifests as, a T cell deficiency. This is usually caused by HIV infection (resulting in AIDS), but may be Idiopathic CD4+ lymphocytopenia (ICL), which is a very rare heterogeneous disorder defined by CD4+ T-cell counts below 300 cells/μL ...
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