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X-ray Crystallography
X-ray crystallography is the experimental science of determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to Diffraction, diffract in specific directions. By measuring the angles and intensities of the X-ray diffraction, a crystallography, crystallographer can produce a three-dimensional picture of the density of electrons within the crystal and the positions of the atoms, as well as their chemical bonds, crystallographic disorder, and other information. X-ray crystallography has been fundamental in the development of many scientific fields. In its first decades of use, this method determined the size of atoms, the lengths and types of chemical bonds, and the atomic-scale differences between various materials, especially minerals and alloys. The method has also revealed the structure and function of many biological molecules, including vitamins, drugs, proteins and nucleic acids such as DNA. X-ray crystall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Freezed XRD
Freezing is a phase transition in which a liquid turns into a solid when its temperature is lowered below its freezing point. For most substances, the melting and freezing points are the same temperature; however, certain substances possess differing solid-liquid transition temperatures. For example, agar displays a hysteresis in its melting point and freezing point. It melts at and solidifies from . Crystallization Most liquids freeze by crystallization, formation of crystalline solid from the uniform liquid. This is a first-order thermodynamic phase transition, which means that as long as solid and liquid coexist, the temperature of the whole system remains very nearly equal to the melting point due to the slow removal of heat when in contact with air, which is a poor heat conductor. Because of the latent heat of fusion, the freezing is greatly slowed and the temperature will not drop anymore once the freezing starts but will continue dropping once it finishes. Crystalli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Design
Drug design, often referred to as rational drug design or simply rational design, is the invention, inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic compound, organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic effect, therapeutic benefit to the patient. In the most basic sense, drug design involves the design of molecules that are complementary in shape and electric charge, charge to the biomolecular target with which they interact and therefore will bind to it. Drug design frequently but not necessarily relies on molecular modelling, computer modeling techniques. This type of modeling is sometimes referred to as computer-aided drug design. Finally, drug design that relies on the knowledge of the three-dimensional structure of the biomolecular target is known as structure-based drug design. In addition to small molec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecule
A molecule is a group of two or more atoms that are held together by Force, attractive forces known as chemical bonds; depending on context, the term may or may not include ions that satisfy this criterion. In quantum physics, organic chemistry, and biochemistry, the distinction from ions is dropped and ''molecule'' is often used when referring to polyatomic ions. A molecule may be homonuclear, that is, it consists of atoms of one chemical element, e.g. two atoms in the oxygen molecule (O2); or it may be heteronuclear, a chemical compound composed of more than one element, e.g. water (molecule), water (two hydrogen atoms and one oxygen atom; H2O). In the kinetic theory of gases, the term ''molecule'' is often used for any gaseous particle regardless of its composition. This relaxes the requirement that a molecule contains two or more atoms, since the noble gases are individual atoms. Atoms and complexes connected by non-covalent interactions, such as hydrogen bonds or ionic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bravais Lattice
In geometry and crystallography, a Bravais lattice, named after , is an infinite array of discrete points generated by a set of discrete translation operations described in three dimensional space by : \mathbf = n_1 \mathbf_1 + n_2 \mathbf_2 + n_3 \mathbf_3, where the ''ni'' are any integers, and a''i'' are ''primitive translation vectors'', or ''primitive vectors'', which lie in different directions (not necessarily mutually perpendicular) and span the lattice. The choice of primitive vectors for a given Bravais lattice is not unique. A fundamental aspect of any Bravais lattice is that, for any choice of direction, the lattice appears exactly the same from each of the discrete lattice points when looking in that chosen direction. The Bravais lattice concept is used to formally define a ''crystalline arrangement'' and its (finite) frontiers. A crystal is made up of one or more atoms, called the ''basis'' or ''motif'', at each lattice point. The ''basis'' may consist of atoms, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Miller Index
Miller indices form a notation system in crystallography for lattice planes in crystal (Bravais) lattices. In particular, a family of lattice planes of a given (direct) Bravais lattice is determined by three integers ''h'', ''k'', and ''ℓ'', the ''Miller indices''. They are written (''hkℓ''), and denote the family of (parallel) lattice planes (of the given Bravais lattice) orthogonal to \mathbf_ = h\mathbf_1 + k\mathbf_2 + \ell\mathbf_3 , where \mathbf_i are the basis or primitive translation vectors of the reciprocal lattice for the given Bravais lattice. (Note that the plane is not always orthogonal to the linear combination of direct or original lattice vectors h\mathbf_1 + k\mathbf_2 + \ell\mathbf_3 because the direct lattice vectors need not be mutually orthogonal.) This is based on the fact that a reciprocal lattice vector \mathbf (the vector indicating a reciprocal lattice point from the reciprocal lattice origin) is the wavevector of a plane wave in the Fouri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Hallowes Miller
Prof William Hallowes Miller FRS HFRSE LLD DCL (6 April 180120 May 1880) was a Welsh mineralogist and laid the foundations of modern crystallography. Miller indices are named after him, the method having been described in his ''Treatise on Crystallography'' (1839). The mineral known as millerite is named after him. Life and work Miller was born in 1801 at Velindre near Llandovery, Carmarthenshire, South Wales. He was educated at St John's College, Cambridge, where he graduated in 1826 as fifth wrangler. He became a Fellow there in 1829. For a few years Miller was occupied as a college tutor and during this time he published treatises on hydrostatics and hydrodynamics. Miller also gave special attention to crystallography, and at 31 years old, on the resignation of William Whewell he succeeded in 1832 to the professorship of mineralogy, a post he held until 1870. Miller's chief work, on ''Crystallography'', was published in 1839. He was elected to the Royal Society in 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Law Of Rational Indices
The law of rational indices is an Empirical research, empirical law in the field of crystallography concerning crystal structure. The law states that "when referred to three intersecting axes all faces occurring on a crystal can be described by numerical indices which are integers, and that these integers are usually small numbers." The law is also named the ''law of rational intercepts'' or the ''second law of crystallography''. Definition The International Union of Crystallography (IUCr) gives the following definition: "The law of rational indices states that the intercepts, ''OP'', ''OQ'', ''OR'', of the natural faces of a crystal form with the unit-cell axes a, b, c are inversely proportional to prime integers, , , . They are called the Miller index, Miller indices of the face. They are usually small because the corresponding lattice planes are among the densest and have therefore a high interplanar spacing and low indices." History The law of constancy of interfacial ang ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
René Just Haüy
René Just Haüy () FRS MWS FRSE (28 February 1743 – 1 June 1822) was a French priest and mineralogist, commonly styled the Abbé Haüy after he was made an honorary canon of Notre-Dame de Paris, Notre Dame. Due to his innovative work on crystal structure and his four-volume ''Traité de Minéralogie'' (1801), he is often referred to as the "Father of Modern Crystallography". During the French Revolution he also helped to establish the metric system. Biography Early life René-Just Haüy was born at Saint-Just-en-Chaussée on February 28, 1743, in the Provinces of France, province of Picardy (later the ''département in France, département'' of Oise). His parents were Just Haüy, a poor linen-weaver, and his wife Magdeleine Candelot. Haüy's interest in the services and music of the local church brought him to the attention of the Prior (ecclesiastical), prior of a nearby abbey of Premonstratensians, Premonstrants. Through him, Haüy was introduced to a colleague in Paris ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Law Of Constancy Of Interfacial Angles
The law of constancy of interfacial angles (; ) is an Empirical research, empirical law in the fields of crystallography and mineralogy concerning the shape, or morphology, of crystals. The law states that the angles between adjacent corresponding faces of crystals of a particular substance are always constant despite the different shapes, sizes, and mode of growth of crystals. The law is also named the ''first law of crystallography'' or ''Nicolas Steno, Steno's law''. Definition The International Union of Crystallography (IUCr) gives the following definition: "The law of the constancy of interfacial angles (or 'first law of crystallography') states that the angles between the crystal faces of a given species are constant, whatever the lateral extension of these faces and the origin of the crystal, and are characteristic of that species." The law is valid at constant temperature and pressure. This law is important in identifying different mineral species as small changes in at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicolas Steno
Niels Steensen (; Latinized to Nicolas Steno or Nicolaus Stenonius; 1 January 1638 – 25 November 1686 ) was a Danish scientist, a pioneer in both anatomy and geology who became a Catholic bishop in his later years. He has been beatified by the Catholic Church. Steensen was trained in the classical texts on science; however, by 1659 he seriously questioned accepted knowledge of the natural world. Importantly he questioned explanations for tear production, the idea that fossils grew in the ground and explanations of rock formation. His investigations and his subsequent conclusions on fossils and rock formation have led scholars to consider him one of the founders of modern stratigraphy and modern geology. The importance of Steensen's foundational contributions to geology may be gauged from the fact that half of the twenty papers in a recent miscellany volume on ''The Revolution in Geology from the Renaissance to the Enlightenment'' focus on Steensen, the "preeminent Baroqu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Snowflake
A snowflake is a single ice crystal that is large enough to fall through the Earth's atmosphere as snow.Knight, C.; Knight, N. (1973). Snow crystals. Scientific American, vol. 228, no. 1, pp. 100–107.Hobbs, P.V. 1974. Ice Physics. Oxford: Clarendon Press. Snow appears white in color despite being made of clear ice. This is because the many small crystal facets of the snowflakes scatter the sunlight between them. Each flake begins by forming around a tiny particle, called its nucleus, accumulating water droplets, which freeze and slowly form a crystal. Complex shapes emerge as the flake moves through differing temperature and humidity zones in the atmosphere, and possibly combines with other snowflakes. Because of this, snowflakes tend to look very different from one another. However, they may be categorized in eight broad classifications and at least 80 individual variants. The main constituent shapes for ice crystals, from which combinations may occur, are ''needle'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Symmetry
Symmetry () in everyday life refers to a sense of harmonious and beautiful proportion and balance. In mathematics, the term has a more precise definition and is usually used to refer to an object that is Invariant (mathematics), invariant under some Transformation (function), transformations, such as Translation (geometry), translation, Reflection (mathematics), reflection, Rotation (mathematics), rotation, or Scaling (geometry), scaling. Although these two meanings of the word can sometimes be told apart, they are intricately related, and hence are discussed together in this article. Mathematical symmetry may be observed with respect to the passage of time; as a space, spatial relationship; through geometric transformations; through other kinds of functional transformations; and as an aspect of abstract objects, including scientific model, theoretic models, language, and music. This article describes symmetry from three perspectives: in mathematics, including geometry, the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
