|
Wyss Institute For Biologically Inspired Engineering
The Wyss Institute for Biologically Inspired Engineering (pronounced "veese") is a cross-disciplinary research institute at Harvard University focused on bridging the gap between academia and industry (translational medicine) by drawing inspiration from nature's design principles to solve challenges in health care and the environment. It is focused on the field of biologically inspired engineering to be distinct from bioengineering and biomedical engineering. The institute also has a focus on applications, intellectual property generation, and commercialization. The Wyss Institute is located in Boston's Longwood Medical Area and has 375 full-time staff. The Wyss is organized around eight focus areas, each of which integrate faculty, postdocs, fellows, and staff scientists. The focus areas are bioinspired therapeutics & diagnostics, diagnostics accelerator, immuno-materials, living cellular devices, molecular robotics, 3D organ engineering, predictive bioanalytics and synthetic bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George M
''George M!'' is a Broadway theatre, Broadway musical based on the life of George M. Cohan, the biggest Broadway star of his day who was known as "The Man Who Owned Broadway." The book for the musical was written by Michael Stewart (playwright), Michael Stewart, John Pascal, and Francine Pascal. Music and lyrics were by George M. Cohan himself, with revisions for the musical by Cohan's daughter, Mary Cohan. The story covers the period from the late 1880s until 1937 and focuses on Cohan's life and show business career from his early days in vaudeville with his parents and sister to his later success as a Broadway singer, dancer, composer, lyricist, theatre director and theatre producer, producer. The show includes such Cohan hit songs as "Give My Regards To Broadway", "You're a Grand Old Flag", and "Yankee Doodle Dandy." Productions The musical opened on Broadway at the Palace Theatre (New York City), Palace Theatre on April 10, 1968, and closed on April 26, 1969, after 433 pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck & Co
Merck & Co., Inc. is an American Multinational corporation, multinational pharmaceutical company headquartered in Rahway, New Jersey. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. It is one of the largest pharmaceutical companies in the world, generally ranking in the global top five by revenue. Merck & Co. was originally established as the American affiliate of Merck Group in 1891. Merck develops and produces medicines, vaccines, biologic therapies and animal health products. It has several blockbuster products, including cancer immunotherapy, anti-diabetic medications, and vaccines for HPV and chickenpox, each generating significant revenue as of 2020. The company is ranked 71st on the 2022 Fortune 500, ''Fortune'' 500 and 87th on the 2022 Forbes Global 2000, ''Forbes'' Global 2000, both based on 2021 revenues. In 2023, the company’s seat in the ''Forbes'' Global 2000 was 73. Products The company develops medicines, vaccines, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johnson & Johnson
Johnson & Johnson (J&J) is an American multinational pharmaceutical, biotechnology, and medical technologies corporation headquartered in New Brunswick, New Jersey, and publicly traded on the New York Stock Exchange. Its common stock is a component of the Dow Jones Industrial Average, and the company is ranked No. 42 on the 2024 ''Fortune'' 500 list of the largest United States corporations. In 2024, the company was ranked 45th in the ''Forbes'' Global 2000. Johnson & Johnson has a global workforce of approximately 138,000 employees who are led by the company's current chairman and chief executive officer, Joaquin Duato. Johnson & Johnson was founded in 1886 by three brothers, Robert Wood Johnson, James Wood Johnson, and Edward Mead Johnson, selling ready-to-use sterile surgical dressings. In 2023, the company split-off its consumer healthcare business segment into a new publicly traded company, Kenvue. The company is exclusively focused on developing and producing ph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emulate
Emulate, Inc. (Emulate) is a biotechnology company that commercialized Organs-on-Chips technology—a human cell-based technology that recreates organ-level function to model organs in healthy and diseased states. The technology has applications in pharmaceutical research, product development, testing how different medicines, chemicals, and foods affect human health. Emulate has also worked with Cedars-Sinai Medical Center on a precision medicine initiative that uses Organs-on-Chips technology in the clinical setting. This initiative is designed to provide clinicians with better data about how an individual patient may respond to treatment. The company also signed a Cooperative Research and Development Agreement (CRADA) with the U.S. Food and Drug Administration to advance and qualify its Human Emulation System to meet regulatory evaluation for product testing. Technology Emulate's Organs-on-Chips technology has been used to recreate the function of a variety of different orga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ-on-a-chip
An organ-on-a-chip (OOC) is a multi-channel 3D microfluidic cell culture, integrated circuit (chip) that simulates the activities, mechanics and physiological response of an entire organ or an organ system. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context. By acting as a more sophisticated ''in vitro'' approximation of complex tissues than standard cell culture, they provide the potential as an alternative to animal models for drug development and toxin testing. Although multiple publications claim to have translated organ functions onto this interface, the development of these microfluidic applications is still in its infancy. Organs-on-chips vary in design and approach between different researchers. Organs that have been simulated by microfluidic devices include brain, lung, heart, kidney, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Startup Company
A startup or start-up is a company or project undertaken by an Entrepreneurship, entrepreneur to seek, develop, and validate a scalable business model. While entrepreneurship includes all new businesses including self-employment and businesses that do not intend to Initial public offering, go public, startups are new businesses that intend to grow large beyond the solo-founder. During the beginning, startups face high uncertainty and have high rates of failure, but a minority of them do go on to become successful and influential, such as unicorn (finance), unicorns.Erin Griffith (2014)Why startups fail, according to their founders, Fortune.com, 25 September 2014; accessed 27 October 2017 Actions Startups typically begin by a founder (solo-founder) or co-founders who have a way to solve a problem. The founder of a startup will do the market validation by problem interview, solution interview, and building a minimum viable product (MVP), i.e. a prototype, to develop and validate thei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pamela Silver
Pamela Ann Silver is an American biologist, bioengineer and professor. She holds the Elliot T. and Onie H. Adams Professorship of Biochemistry and Systems Biology at Harvard Medical School in the Department of Systems Biology. Silver is one of the founding Core Faculty Members of the Wyss Institute for Biologically Inspired Engineering at Harvard University. She has made contributions to the fields of cell and nuclear biology, systems biology, RNA biology, cancer therapeutics, international policy research, and graduate education. Silver was the first director of the Harvard University Graduate Program in Systems Biology. She serves as a member of the National Science Advisory Board for Biosecurity. Early life and education Silver grew up in Atherton, California, where she attended Laurel and Encinal Elementary Schools. During this time, she was a winner of the IBM Math Competition, winning a slide rule, and received special recognition for her early aptitude in science. Sh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radhika Nagpal
Radhika Nagpal is an Indian-American computer scientist and researcher in the fields of self-organising computer systems, biologically-inspired robotics, and biological multi-agent systems. She is currently the Norman R. Augustine '57*59 Professor in Robotics in the Departments of Mechanical and Aerospace Engineering and Computer Science at Princeton University. Education and academic career Nagpal received an S.B. and S.M. in electrical engineering and computer science from the Massachusetts Institute of Technology in 1994, and a Ph.D. in electrical engineering and computer science from MIT in 2001. Her dissertation, "Programmable Self-Assembly using Biologically-Inspired Local Interactions and Origami Mathematics", was supervised by Gerald Sussman and Harold Abelson. In it, she presented a language for instructing a sheet of identically-programmed agents to self-assemble into a desired shape making use only of local interactions, and in a manner robust to irregularities, co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lakshminarayanan Mahadevan
Lakshminarayanan Mahadevan is an Indian-American scientist. He is currently the Lola England de Valpine Professor of Applied Mathematics, Organismic and Evolutionary Biology and Physics at Harvard University. His work centers around understanding the organization of matter in space and time (that is, how it is shaped and how it flows, particularly at the scale observable by the unaided senses, in both physical and biological systems). Mahadevan is a 2009 MacArthur Fellow. Education Mahadevan graduated from the Indian Institute of Technology, Madras, and then received an M.S. from the University of Texas at Austin, and an M.S. and Ph.D. from Stanford University in 1995. Career and research He started his independent career on the faculty at the Massachusetts Institute of Technology in 1996. In 2000, he was elected the inaugural Schlumberger Professor of Complex Physical Systems in the Department of Applied Mathematics and Theoretical Physics, and a professorial fellow of Trini ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Collins (bioengineer)
James J. Collins (born June 26, 1965) is an American biomedical engineer and bioengineer who serves as the Termeer Professor of Medical Engineering & Science at the Massachusetts Institute of Technology (MIT), where he is also a director at the MIT Jameel Clinic, MIT Abdul Latif Jameel Clinic for Machine Learning in Health. Collins conducted research showing that artificial intelligence (AI) approaches can be used to discover novel antibiotics, such as halicin and abaucin. He serves as the director of the Antibiotics-AI Project at MIT, which is supported by The Audacious Project, and is a member of the Harvard–MIT Program in Health Sciences and Technology. He is also a core faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University and a member of the Broad Institute. Collins is one of the founders of the field of synthetic biology, and his work on synthetic gene circuits and programmable cells has led to the development of new classes o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
