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Woese
Carl Richard Woese (; July 15, 1928 – December 30, 2012) was an American microbiologist and biophysicist. Woese is famous for defining the Archaea (a new domain of life) in 1977 through a pioneering phylogenetic taxonomy of 16S ribosomal RNA, a technique that has revolutionized microbiology. He also originated the RNA world hypothesis in 1967, although not by that name. Woese held the Stanley O. Ikenberry Chair and was professor of microbiology at the University of Illinois at Urbana–Champaign. Life and education Carl Woese was born in Syracuse, New York on July 15, 1928. Woese attended Deerfield Academy in Massachusetts. He received a bachelor's degree in mathematics and physics from Amherst College in 1950. During his time at Amherst, Woese took only one biology course (Biochemistry, in his senior year) and had "no scientific interest in plants and animals" until advised by William M. Fairbank, then an assistant professor of physics at Amherst, to pursue biophysics at Ya ...
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Archaea
Archaea ( ; singular archaeon ) is a domain of single-celled organisms. These microorganisms lack cell nuclei and are therefore prokaryotes. Archaea were initially classified as bacteria, receiving the name archaebacteria (in the Archaebacteria kingdom), but this term has fallen out of use. Archaeal cells have unique properties separating them from the other two domains, Bacteria and Eukaryota. Archaea are further divided into multiple recognized phyla. Classification is difficult because most have not been isolated in a laboratory and have been detected only by their gene sequences in environmental samples. Archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat, square cells of '' Haloquadratum walsbyi''. Despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes invo ...
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Domain (biology)
In biological taxonomy, a domain ( or ) ( Latin: ''regio''), also dominion, superkingdom, realm, or empire, is the highest taxonomic rank of all organisms taken together. It was introduced in the three-domain system of taxonomy devised by Carl Woese, Otto Kandler and Mark Wheelis in 1990. According to the domain system, the tree of life consists of either three domains such as Archaea, Bacteria, and Eukarya, or two domains consisting of Archaea and Bacteria, with Eukarya included in Archaea. The first two are all prokaryotes, single-celled microorganisms without a membrane-bound nucleus. All organisms that have a cell nucleus and other membrane-bound organelles are included in Eukarya. Non-cellular life is not included in this system. Alternatives to the three-domain system include the earlier two-empire system (with the empires Prokaryota and Eukaryota), and the eocyte hypothesis (with two domains of Bacteria and Archaea, with Eukarya included as a branch of A ...
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16S Ribosomal RNA
16 S ribosomal RNA (or 16 S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome ( SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure. The genes coding for it are referred to as 16S rRNA gene and are used in reconstructing phylogenies, due to the slow rates of evolution of this region of the gene. Carl Woese and George E. Fox were two of the people who pioneered the use of 16S rRNA in phylogenetics in 1977. Multiple sequences of the 16S rRNA gene can exist within a single bacterium. Functions * Like the large (23S) ribosomal RNA, it has a structural role, acting as a scaffold defining the positions of the ribosomal proteins. * The 3-end contains the anti- Shine-Dalgarno sequence, which binds upstream to the AUG start codon on the mRNA. The 3-end of 16S RNA binds to the proteins S1 and S21 which are known to be involved in initiation of protein synthesis * Interacts with 23S, aiding in the binding of the two ribo ...
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Taxonomy (biology)
In biology, taxonomy () is the scientific study of naming, defining ( circumscribing) and classifying groups of biological organisms based on shared characteristics. Organisms are grouped into taxa (singular: taxon) and these groups are given a taxonomic rank; groups of a given rank can be aggregated to form a more inclusive group of higher rank, thus creating a taxonomic hierarchy. The principal ranks in modern use are domain, kingdom, phylum (''division'' is sometimes used in botany in place of ''phylum''), class, order, family, genus, and species. The Swedish botanist Carl Linnaeus is regarded as the founder of the current system of taxonomy, as he developed a ranked system known as Linnaean taxonomy for categorizing organisms and binomial nomenclature for naming organisms. With advances in the theory, data and analytical technology of biological systematics, the Linnaean system has transformed into a system of modern biological classification intended to reflect the ...
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RNA World Hypothesis
The RNA world is a hypothetical stage in the evolutionary history of life on Earth, in which self-replicating RNA molecules proliferated before the evolution of DNA and proteins. The term also refers to the hypothesis that posits the existence of this stage. Alexander Rich first proposed the concept of the RNA world in 1962, and Walter Gilbert coined the term in 1986. Alternative chemical paths to life have been proposed, and RNA-based life may not have been the first life to exist. Even so, the evidence for an RNA world is strong enough that the hypothesis has gained wide acceptance. The concurrent formation of all four RNA building blocks further strengthened the hypothesis. Regardless of its plausibility in a prebiotic scenario, the RNA world can serve as a model system for studying the origin of life. Like DNA, RNA can store and replicate genetic information; like protein enzymes, RNA enzymes (ribozymes) can catalyze (start or accelerate) chemical reactions that are cr ...
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Crafoord Prize
The Crafoord Prize is an annual science prize established in 1980 by Holger Crafoord, a Swedish industrialist, and his wife Anna-Greta Crafoord. The Prize is awarded in partnership between the Royal Swedish Academy of Sciences and the Crafoord Foundation in Lund. The Academy is responsible for selecting the Crafoord Laureates. The prize is awarded in four categories: astronomy and mathematics; geosciences; biosciences, with particular emphasis on ecology; and polyarthritis, the disease from which Holger severely suffered in his last years. According to the Academy, "these disciplines are chosen so as to complement those for which the Nobel Prizes are awarded". Only one award is given each year, according to a rotating scheme – astronomy and mathematics; then geosciences; then biosciences. A Crafoord Prize in polyarthritis is only awarded when a special committee decides that substantial progress in the field has been made. The recipient of the Crafoord Prize is announced eac ...
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David Stahl (biologist)
David A. Stahl is an American scientist and Professor of Environmental Engineering. He is best known for the application of molecular microbial ecology to environmental engineering. Biography Stahl received his B.S. in microbiology from the University of Washington, ''cum laude'', in 1971. He earned his M.S. and his Ph.D. in microbiology at the University of Illinois in 1975 and 1978, respectively. From 1978 to 1980, he completed postdoctoral training at the National Jewish Hospital and Research Center, where he was a Senior Research Associate from 1980 to 1984. From 1984 to 1994, he was on the faculty of the University of Illinois. From 1994 to 2000, he was on the faculty of Northwestern University. Since 2000, he has been a member of the faculty of the University of Washington. Stahl is a Fellow of the American Academy of Microbiology. He was elected to the National Academy of Engineering in 2012. He was the editor of FEMS Microbiology Letters from 1990 to 1996, editor of Bio ...
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Leeuwenhoek Medal
The Leeuwenhoek Medal, established in 1877 by the Royal Netherlands Academy of Arts and Sciences (KNAW), in honor of the 17th- and 18th-century microscopist Antoni van Leeuwenhoek, is granted every ten years to the scientist judged to have made the most significant contribution to microbiology during the preceding decade. From 2015 the Royal Dutch Society for Microbiology (KNVM) will be awarding the Leeuwenhoek Medal. Recipients SourceKNVM*1877 Christian Gottfried Ehrenberg, Germany *1885 Ferdinand Cohn, Germany *1895 Louis Pasteur, France *1905 Martinus Beijerinck, Netherlands *1915 Sir David Bruce, United Kingdom *1925 Félix d'Herelle, (at the time) Egypt *1935 Sergei Nikolaevitch Winogradsky, France *1950 Selman Abraham Waksman, United States *1960 André Lwoff, France *1970 Cornelius Bernardus van Niel (Kees van Niel), United States *1981 Roger Yate Stanier, France *1992 Carl Woese, United States *2003 Karl Stetter, Germany *2015 Craig Venter, United States of America ...
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University Of Illinois At Urbana–Champaign
The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the University of Illinois system and was founded in 1867. Enrolling over 56,000 undergraduate and graduate students, the University of Illinois is one of the largest public universities by enrollment in the country. The University of Illinois Urbana-Champaign is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". In fiscal year 2019, research expenditures at Illinois totaled $652 million. The campus library system possesses the second-largest university library in the United States by holdings after Harvard University. The university also hosts the National Center for Supercomputing Applications and is home to the fastest supercomputer on a university campus. ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research.Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells, Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function. Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenom ...
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William M
William is a masculine given name of Norman French origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Liam, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the German given name ''Wilhelm''. Both ultimately descend from Proto-Germanic ''*Wiljahelmaz'', with a direct cognate also in the Old Norse name ''Vilhjalmr'' and a West Germanic borrowing into Medieval Latin ''Willelmus''. The Proto-Germani ...
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Yale
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate coll ...
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