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Wikiproteins
WikiProfessional (Wiki for Professionals) was an attempt to create a web-based research environment for semantic searching, providing an intuitive tool for analyzing and relating concepts. When data is entered, the system semantically analyzed and recognized co-occurrences between different entities. The results were visualized through a "Knowlet," which is a visual representation of semantic distance between associated entities. This Knowlet is then used to notify persons that have subscribed to these entities, enabling a rapid data interchange between collaborators. The major focus was proteins, using a portal named WikiProteins. It contained over a hundred million entries, "melding some of the key biomedical databases into a single information resource". Sources included: * 245,000 Proteins from UniProt/Swiss-Prot * 24,000 Gene Ontology terms from the GO Consortium * 880,000 Concepts from UMLS/ NLM * 112,000,000 Unique sentences from Medline The project never passed the op ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantic Search
Semantic search denotes search with meaning, as distinguished from lexical search where the search engine looks for literal matches of the query words or variants of them, without understanding the overall meaning of the query. Semantic search seeks to improve search accuracy by understanding the searcher's intent and the contextual meaning of terms as they appear in the searchable dataspace, whether on the Web or within a closed system, to generate more relevant results. Some authors regard semantic search as a set of techniques for retrieving knowledge from richly structured data sources like ontologies and XML as found on the Semantic Web. Such technologies enable the formal articulation of domain knowledge at a high level of expressiveness and could enable the user to specify their intent in more detail at query time. The articulation enhances content relevance and depth by including specific places, people, or concepts relevant to the query. Knowledge Graphs Tools like Goog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medline
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care. MEDLINE also covers much of the literature in biology and biochemistry, as well as fields such as molecular evolution. Compiled by the United States National Library of Medicine (NLM), MEDLINE is freely available on the Internet and searchable via PubMed and NLM's National Center for Biotechnology Information's Entrez system. History MEDLARS (Medical Literature Analysis and Retrieval System) was a computerised biomedical bibliographic retrieval system. It was launched by the National Library of Medicine in 1964 and was the first large-scale, computer-based, retrospective search service available to the general public. Initial development of MEDLARS Since ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Free-content Websites
Free content, libre content, libre information, or free information is any kind of creative work, such as a work of art, a book, a software program, or any other creative content for which there are very minimal copyright and other legal limitations on usage, modification and distribution. These are works or expressions which can be freely studied, applied, copied and modified by anyone for any purpose including, in some cases, commercial purposes. Free content encompasses all works in the public domain and also those copyrighted works whose licenses honor and uphold the definition of free cultural work. In most countries, the Berne Convention grants copyright holders control over their creations by default. Therefore, copyrighted content must be explicitly declared free by the authors, which is usually accomplished by referencing or including licensing statements from within the work. The right to reuse such a work is granted by the authors in a license known as a free lice ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metadata
Metadata (or metainformation) is "data that provides information about other data", but not the content of the data itself, such as the text of a message or the image itself. There are many distinct types of metadata, including: * Descriptive metadata – the descriptive information about a resource. It is used for discovery and identification. It includes elements such as title, abstract, author, and keywords. * Structural metadata – metadata about containers of data and indicates how compound objects are put together, for example, how pages are ordered to form chapters. It describes the types, versions, relationships, and other characteristics of digital materials. * Administrative metadata – the information to help manage a resource, like resource type, and permissions, and when and how it was created. * Reference metadata – the information about the contents and quality of Statistical data type, statistical data. * Statistical metadata – also called process data, may ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leiden University Medical Centre
Leiden University Medical Center (Dutch: ''Leids Universitair Medisch Centrum'') or LUMC is the university hospital affiliated with Leiden University, of which it forms the medical faculty. It is located in Leiden, Netherlands. LUMC is a modern university medical center for research, education and patient care. Its research practice ranges from pure fundamental medical research to applied clinical research. Patient care The hospital has clinical departments of all medicine, medical specialties, and acts as a tertiary referral centre for the northern part of the province of South Holland. Special units include: * Ophthalmology * Neurosurgery * Cardiothoracic surgery * Neonatal and pediatric surgery and intensive care * Pediatric oncology * Orthopedic medicine * Biliary surgery * Rheumatology * Level I trauma center Research The LUMC aims at identifying the causes of disease, improving diagnosis, prevention, and ultimately developing effective treatments. Within LUMC different s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erasmus MC
Erasmus University Medical Center (Erasmus MC or EMC) is a teaching hospital based in Rotterdam, Netherlands, affiliated with Erasmus University and home to its faculty of medicine. It is the largest and one of the most authoritative scientific university medical centers in Europe. The hospital is the largest of the eight university medical centers in the Netherlands, both in terms of turnover and number of beds. The Erasmus MC ranks #1 among the top European institution in clinical medicine and #20 in the world, according to the Times Higher Education rankings. Structure The hospital has three locations: * Erasmus MC – the main location. * Erasmus MC Sophia Children's Hospital, the pediatric hospital, closely connected to the main location by a raised glass hallway. * Erasmus MC Cancer Institute, specialized in oncology. Special units include: * Neurosurgery * Cardiothoracic surgery * Neonatal and pediatric surgery and intensive care * Pediatric oncology * Level I trauma cente ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barend Mons
Barend Mons (born 1957, The Hague) is a molecular biologist and a FAIR data specialist. The first decade of his scientific career he spent on fundamental research on malaria parasites and later on translational research for malaria vaccines. In the year 2000 he switched to advanced data stewardship and (biological) systems analytics. He is most known for innovations in scholarly collaboration, especially nanopublications, and knowledge graph based discovery. In 2012 Barend was appointed full Professor in biosemantics in the Department of Human Genetics at the Leiden University Medical Center (LUMC) in The Netherlands. In 2014 he organised the seminal FAIR conference at the Lorentz centre that led to the FAIR data initiative and GO FAIR. In 2015 he was appointed chair of the High Level Expert Group on the European Open Science Cloud. From 2018 to 2023 Barend was the elected president of CODATA, the affiliated organisation on research data related issues of the Internation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States National Library Of Medicine
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is an institute within the National Institutes of Health. Its collections include more than seven million books, journals, technical reports, manuscripts, microfilms, photographs, and images on medicine and related sciences, including some of the world's oldest and rarest works. the acting director of the NLM was Stephen Sherry. History The precursor of the National Library of Medicine, established in 1836, was the Library of the Surgeon General's Office, a part of the office of the Surgeon General of the United States Army. The Armed Forces Institute of Pathology and its Medical Museum were founded in 1862 as the Army Medical Museum. Throughout their history the Library of the Surgeon General's Office and the Army Medical Museum often shared quarters. From 1866 to 1887, they were ho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantics (computer Science)
In programming language theory, semantics is the rigorous mathematical study of the meaning of programming languages. Semantics assigns computational meaning to valid strings in a programming language syntax. It is closely related to, and often crosses over with, the semantics of mathematical proofs. Semantics describes the processes a computer follows when executing a program in that specific language. This can be done by describing the relationship between the input and output of a program, or giving an explanation of how the program will be executed on a certain platform, thereby creating a model of computation. History In 1967, Robert W. Floyd published the paper ''Assigning meanings to programs''; his chief aim was "a rigorous standard for proofs about computer programs, including proofs of correctness, equivalence, and termination". Floyd further wrote: A semantic definition of a programming language, in our approach, is founded on a syntactic definition. It mu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UMLS
The Unified Medical Language System (UMLS) is a compendium of many controlled vocabulary, controlled vocabularies in the biomedical sciences (created 1986). It provides a mapping structure among these vocabularies and thus allows one to translate among the various terminology systems; it may also be viewed as a comprehensive thesaurus and ontology (computer science), ontology of biomedical concepts. UMLS further provides facilities for natural language processing. It is intended to be used mainly by developers of systems in medical informatics. UMLS consists of Knowledge Sources (databases) and a set of software tools. The UMLS was designed and is maintained by the United States, US National Library of Medicine, is updated quarterly and may be used for free. The project was initiated in 1986 by Donald A.B. Lindberg, Doctor of Medicine, M.D., then Director of the Library of Medicine, and directed by Betsy Humphreys. Purpose and applications The number of biomedical resources ava ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Ontology
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access to all aspects of the data provided by the project, and to enable functional interpretation of experimental data using the GO, for example via enrichment analysis. GO is part of a larger classification effort, the Open Biomedical Ontologies, being one of the Initial Candidate Members of the OBO Foundry. Whereas gene nomenclature focuses on gene and gene products, the Gene Ontology focuses on the function of the genes and gene products. The GO also extends the effort by using a markup language to make the data (not only of the genes and their products but also of curated attributes) machine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
