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Widal
Georges-Fernand-Isidor Widal (March 9, 1862 in Dellys, Algeria – January 14, 1929 in Paris) was a French people, French physician. From 1886 to 1888 he devoted himself to public demonstrations of the researches of the faculty of pathological anatomy, and during the two years following was in charge of a course in bacteriology in the laboratory of Professor Victor André Cornil (1837–1908) in Paris. In 1895 he was appointed visiting physician to the hospitals of Paris, and in 1904 became an professor, instructor in the faculty of medicine. In 1905 he became a physician to the Hôpital Cochin, and was in charge of the medical clinics at the same institution. During the WWI, he developed a vaccine against typhoid fever which reduced the spread of this disease in French army and more generally allied troops. Widal was the author of a remarkable series of essays on infectious diseases, erysipelas, diseases of the heart (anatomy), heart, liver, nervous system, etc., besides being a ...
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Widal Test
The Widal test, developed in 1896 and named after its inventor, Georges-Fernand Widal, is an indirect agglutination test for enteric fever or undulant fever whereby bacteria causing typhoid fever are mixed with a serum containing specific antibodies obtained from an infected individual. In cases of ''Salmonella'' infection, the test assesses for host antibodies to the O soma antigen and the H flagellar antigen of the bacteria. False positive and false negative results may occur. Test results need to be interpreted carefully to account for any history of enteric fever, typhoid vaccination, and the general level of antibodies in the populations in endemic areas of the world. As with all serological tests, the rise in antibody levels needed to perform the diagnosis takes 7–14 days, which limits its applicability in early diagnosis. Other means of diagnosing '' Salmonella typhi'' (and '' paratyphi'') include cultures of blood, urine and faeces. These organisms produce H2S from th ...
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