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Warren Gish
Warren Richard Gish is the owner of Advanced Biocomputing LLC. He joined Washington University in St. Louis as a junior faculty member in 1994, and was a Research Associate Professor of Genetics from 2002 to 2007. Education After initially studying physics, Gish obtained an A.B. degree in Biochemistry from University of California, Berkeley, and completed work for his Ph.D. degree in Molecular Biology at the same institution in 1988. Research Gish is primarily known for his contributions to NCBI BLAST, his creation of the BLAST Network Service and nr (non-redundant) databases, his 1996 release of the original gapped BLAST ( WU-BLAST 2.0), and most recently his development and support of AB-BLAST. At Washington University in St. Louis, Gish also led the genome analysis group which annotated all finished human, mouse and rat genome data produced by the University's Genome Sequencing Center from 1995 through 2002. As a graduate student, Gish applied the Quine-McCluskey alg ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., federal district, five major unincorporated territories, nine United States Minor Outlying Islands, Minor Outlying Islands, and 326 Indian reservations. The United States is also in Compact of Free Association, free association with three Oceania, Pacific Island Sovereign state, sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Palau, Republic of Palau. It is the world's List of countries and dependencies by area, third-largest country by both land and total area. It shares land borders Canada–United States border, with Canada to its north and Mexico–United States border, with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the List of ...
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Finite-state Machine
A finite-state machine (FSM) or finite-state automaton (FSA, plural: ''automata''), finite automaton, or simply a state machine, is a mathematical model of computation. It is an abstract machine that can be in exactly one of a finite number of '' states'' at any given time. The FSM can change from one state to another in response to some inputs; the change from one state to another is called a ''transition''. An FSM is defined by a list of its states, its initial state, and the inputs that trigger each transition. Finite-state machines are of two types— deterministic finite-state machines and non-deterministic finite-state machines. A deterministic finite-state machine can be constructed equivalent to any non-deterministic one. The behavior of state machines can be observed in many devices in modern society that perform a predetermined sequence of actions depending on a sequence of events with which they are presented. Simple examples are vending machines, which dispens ...
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UniPro
UniPro (or Unified Protocol) is a high-speed interface technology for interconnecting integrated circuits in mobile and mobile-influenced electronics. The various versions of the UniPro protocol are created within the MIPI Alliance (Mobile Industry Processor Interface Alliance), an organization that defines specifications targeting mobile and mobile-influenced applications. The UniPro technology and associated physical layers aim to provide high-speed data communication (gigabits/second), low-power operation (low swing signaling, standby modes), low pin count (serial signaling, multiplexing), small silicon area (small packet sizes), data reliability (differential signaling, error recovery) and robustness (proven networking concepts, including congestion management). UniPro version 1.6 concentrates on enabling high-speed point to point communication between chips in mobile electronics. UniPro has provisions for supporting networks consisting of up to 128 UniPro devices (integrated ...
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FASTN
FASTA is a DNA and protein sequence alignment software package first described by David J. Lipman and William R. Pearson in 1985. Its legacy is the FASTA format which is now ubiquitous in bioinformatics. History The original FASTA program was designed for protein sequence similarity searching. Because of the exponentially expanding genetic information and the limited speed and memory of computers in the 1980s heuristic methods were introduced aligning a query sequence to entire data-bases. FASTA, published in 1987, added the ability to do DNA:DNA searches, translated protein:DNA searches, and also provided a more sophisticated shuffling program for evaluating statistical significance. There are several programs in this package that allow the alignment of protein sequences and DNA sequences. Nowadays, increased computer performance makes it possible to perform searches for local alignment detection in a database using the Smith–Waterman algorithm. FASTA is pronounced "fa ...
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Genbank
The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. It is produced and maintained by the National Center for Biotechnology Information (NCBI; a part of the National Institutes of Health in the United States) as part of the International Nucleotide Sequence Database Collaboration (INSDC). GenBank and its collaborators receive sequences produced in laboratories throughout the world from more than 500,000 formally described species. The database started in 1982 by Walter Goad and Los Alamos National Laboratory. GenBank has become an important database for research in biological fields and has grown in recent years at an exponential rate by doubling roughly every 18 months. Release 250.0, published in June 2022, contained over 17 trillion nucleotide bases in more than 2,45 billion sequences. GenBank is built by direct submissions from individual laboratories, as well as from bulk submiss ...
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David J
David John Haskins (born 24 April 1957, Northampton, Northamptonshire, England), better known as David J, is a British alternative rock musician, producer, and writer. He is the bassist for the gothic rock band Bauhaus and for Love and Rockets. He has composed the scores for a number of plays and films, and also wrote and directed his own plays, ''Silver for Gold (The Odyssey of Edie Sedgwick)'', in 2008, which was restaged at REDCAT in Los Angeles in 2011, and ''The Chanteuse and The Devil's Muse'' in 2011. His artwork has been shown in galleries internationally, and he has been a resident DJ at venues such as the Knitting Factory. David J has released a number of singles and solo albums, and in 1990 he released one of the first No. 1 hits on the then nascent Modern Rock Tracks charts, with "I'll Be Your Chauffeur". His most recent single, "The Day That David Bowie Died" entered the UK vinyl singles chart at number 4 in 2016. The track appears on his double album, ''V ...
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William R
William is a masculine given name of Norman French origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Liam, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the German given name ''Wilhelm''. Both ultimately descend from Proto-Germanic ''*Wiljahelmaz'', with a direct cognate also in the Old Norse name ''Vilhjalmr'' and a West Germanic borrowing into Medieval Latin ''Willelmus''. The Proto-Germa ...
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FASTA
FASTA is a DNA and protein sequence alignment software package first described by David J. Lipman and William R. Pearson in 1985. Its legacy is the FASTA format which is now ubiquitous in bioinformatics. History The original FASTA program was designed for protein sequence similarity searching. Because of the exponentially expanding genetic information and the limited speed and memory of computers in the 1980s heuristic methods were introduced aligning a query sequence to entire data-bases. FASTA, published in 1987, added the ability to do DNA:DNA searches, translated protein:DNA searches, and also provided a more sophisticated shuffling program for evaluating statistical significance. There are several programs in this package that allow the alignment of protein sequences and DNA sequences. Nowadays, increased computer performance makes it possible to perform searches for local alignment detection in a database using the Smith–Waterman algorithm. FASTA is pronounced "f ...
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Margaret J
Margaret is a female first name, derived via French () and Latin () from grc, μαργαρίτης () meaning "pearl". The Greek is borrowed from Persian. Margaret has been an English name since the 11th century, and remained popular throughout the Middle Ages. It became less popular between the 16th century and 18th century, but became more common again after this period, becoming the second-most popular female name in the United States in 1903. Since this time, it has become less common, but was still the ninth-most common name for women of all ages in the United States as of the 1990 census. Margaret has many diminutive forms in many different languages, including Maggie, Madge, Daisy, Margarete, Marge, Margo, Margie, Marjorie, Meg, Megan, Rita, Greta, Gretchen, and Peggy. Name variants Full name * ( Irish) * ( Irish) * ( Dutch), (German), (Swedish) * ( English) Diminutives * ( English) * ( English) First half * (French) * (Welsh) Second half * ...
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Alfred V
Alfred may refer to: Arts and entertainment *'' Alfred J. Kwak'', Dutch-German-Japanese anime television series * ''Alfred'' (Arne opera), a 1740 masque by Thomas Arne * ''Alfred'' (Dvořák), an 1870 opera by Antonín Dvořák *"Alfred (Interlude)" and "Alfred (Outro)", songs by Eminem from the 2020 album '' Music to Be Murdered By'' Business and organisations * Alfred, a radio station in Shaftesbury, England * Alfred Music, an American music publisher * Alfred University, New York, U.S. * The Alfred Hospital, a hospital in Melbourne, Australia People * Alfred (name) includes a list of people and fictional characters called Alfred * Alfred the Great (848/49 – 899), or Alfred I, a king of the West Saxons and of the Anglo-Saxons Places Antarctica * Mount Alfred (Antarctica) Australia * Alfredtown, New South Wales * County of Alfred, South Australia Canada * Alfred and Plantagenet, Ontario * Alfred Island, Nunavut * Mount Alfred, British Columbia United States * Al ...
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Moore Machine
In the theory of computation, a Moore machine is a finite-state machine whose current output values are determined only by its current state. This is in contrast to a Mealy machine, whose output values are determined both by its current state and by the values of its inputs. Like other finite state machines, in Moore machines, the input typicallinfluences the next state Thus the input may indirectly influence subsequent outputs, but not the current or immediate output. The Moore machine is named after Edward F. Moore, who presented the concept in a 1956 paper, “ Gedanken-experiments on Sequential Machines.” Formal definition A Moore machine can be defined as a 6-tuple (Q, q_0, \Sigma, O, \delta, G) consisting of the following: * A finite set of states Q * A start state (also called initial state) q_0 which is an element of Q * A finite set called the input alphabet \Sigma * A finite set called the output alphabet O * A transition function \delta : Q \times \Sigma \right ...
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