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Walther Flemming
Walther Flemming (21 April 1843 – 4 August 1905) was a German biologist and a founder of cytogenetics. He was born in Sachsenberg (now part of Schwerin) as the fifth child and only son of the psychiatrist Carl Friedrich Flemming (1799–1880) and his second wife, Auguste Winter. He graduated from the ''Gymnasium der Residenzstadt'', where one of his colleagues and lifelong friends was writer Heinrich Seidel. Career Flemming trained in medicine at the University of Prague, graduating in 1868. Afterwards, he served in 1870–71 as a military physician in the Franco-Prussian War. From 1873 to 1876 he worked as a teacher at the University of Prague. In 1876 he accepted a post as a professor of anatomy at the University of Kiel. He became the director of the Anatomical Institute and stayed there until his death. With the use of aniline dyes he was able to find a structure which strongly absorbed basophilic dyes, which he named chromatin. He identified that chromatin was corr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Schwerin
Schwerin (; Mecklenburgisch-Vorpommersch dialect, Mecklenburgisch-Vorpommersch Low German: ''Swerin''; Polabian language, Polabian: ''Zwierzyn''; Latin: ''Suerina'', ''Suerinum'') is the Capital city, capital and List of cities and towns in Germany, second-largest city of the northeastern States of Germany, German state of Mecklenburg-Vorpommern as well as of the region of Mecklenburg, after Rostock. It has around 96,000 inhabitants, and is thus the least populous of all German state capitals. Schwerin is located on the southwestern shore of Lake Schwerin (''Schweriner See''), the second-largest lake of the Mecklenburg Lake Plateau after the Müritz, and there are eleven other lakes within Schwerin's city limits. The city is surrounded by the district of Nordwestmecklenburg, Northwestern Mecklenburg to the north, and the district of Ludwigslust-Parchim to the south. Schwerin and the two surrounding districts form the eastern outskirts of the Hamburg Metropolitan Region. The name ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Franco-Prussian War
The Franco-Prussian War or Franco-German War, often referred to in France as the War of 1870, was a conflict between the Second French Empire and the North German Confederation led by the Kingdom of Prussia. Lasting from 19 July 1870 to 28 January 1871, the conflict was caused primarily by France's determination to reassert its dominant position in continental Europe, which appeared in question following the decisive Austro-Prussian War, Prussian victory over Austria in 1866. According to some historians, Prussian chancellor Otto von Bismarck deliberately provoked the French into declaring war on Prussia in order to induce four independent southern German states—Grand Duchy of Baden, Baden, Kingdom of Württemberg, Württemberg, Kingdom of Bavaria, Bavaria and Grand Duchy of Hesse, Hesse-Darmstadt—to join the North German Confederation. Other historians contend that Bismarck exploited the circumstances as they unfolded. All agree that Bismarck recognized the potential for new ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rudolf Virchow
Rudolf Ludwig Carl Virchow ( ; ; 13 October 18215 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician. He is known as "the father of modern pathology" and as the founder of social medicine, and to his colleagues, the "Pope of medicine". Virchow studied medicine at the Friedrich Wilhelm University under Johannes Peter Müller. While working at the Charité hospital, his investigation of the 1847–1848 typhus epidemic in Upper Silesia laid the foundation for public health in Germany, and paved his political and social careers. From it, he coined a well known aphorism: "Medicine is a social science, and politics is nothing else but medicine on a large scale". His participation in the Revolution of 1848 led to his expulsion from Charité the next year. He then published a newspaper ''Die Medizinische Reform'' (''The Medical Reform''). He took the first Chair of Pathological Anatomy at the University of Wü ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salamander
Salamanders are a group of amphibians typically characterized by their lizard-like appearance, with slender bodies, blunt snouts, short limbs projecting at right angles to the body, and the presence of a tail in both larvae and adults. All ten extant salamander families are grouped together under the order Urodela, the sole surviving order from the group Caudata. ''Urodela'' is a scientific Latin term based on the Ancient Greek : ourà dēlē "conspicuous tail". ''Caudata'' is the Latin for "tailed ones", from : "tail". Salamander diversity is highest in eastern North America, especially in the Appalachian Mountains; most species are found in the Holarctic realm, with some species present in the Neotropical realm. Salamanders never have more than four toes on their front legs and five on their rear legs, but some species have fewer digits and others lack hind limbs. Their permeable skin usually makes them reliant on habitats in or near water or other cool, damp places. So ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gill
A gill () is a respiration organ, respiratory organ that many aquatic ecosystem, aquatic organisms use to extract dissolved oxygen from water and to excrete carbon dioxide. The gills of some species, such as hermit crabs, have adapted to allow respiration on land provided they are kept moist. The microscopic structure of a gill presents a large surface area to the external environment. Branchia (: branchiae) is the zoologists' name for gills (from Ancient Greek ). With the exception of some aquatic insects, the filaments and lamella (surface anatomy), lamellae (folds) contain blood or Coelom#Coelomic fluid, coelomic fluid, from which gases are exchanged through the thin walls. The blood carries oxygen to other parts of the body. Carbon dioxide passes from the blood through the thin gill tissue into the water. Gills or gill-like organs, located in different parts of the body, are found in various groups of aquatic animals, including Mollusc, molluscs, crustaceans, insects, fish, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In drug discovery, for example, verification of efficacy ''in vivo'' is crucial, because ''in vitro'' assays can sometimes yield misleading results with drug c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Division
Cell division is the process by which a parent cell (biology), cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome(s) before dividing. In eukaryotes, there are two distinct types of cell division: a vegetative division (mitosis), producing daughter cells genetically identical to the parent cell, and a cell division that produces Haploidisation, haploid gametes for sexual reproduction (meiosis), reducing the number of chromosomes from two of each type in the diploid parent cell to one of each type in the daughter cells. Mitosis is a part of the cell cycle, in which, replicated chromosomes are separated into two new Cell nucleus, nuclei. Cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. In general, mitosis (division of the nucleus) is preceded by the S stage of interphase (during which the DNA replication occurs) and is f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edouard Van Beneden
Édouard Joseph Louis Marie Van Beneden (5 March 1846 in Leuven – 28 April 1910 in Liège) was a Belgian embryologist, cytologist and marine biologist. He was professor of zoology at the University of Liège. He contributed to cytogenetics by his works on the roundworm '' Ascaris''. In this work he discovered how chromosomes organized meiosis (the production of gametes). He is son of Pierre-Joseph Van Beneden, a zoologist Zoology ( , ) is the scientific study of animals. Its studies include the structure, embryology, classification, habits, and distribution of all animals, both living and extinct, and how they interact with their ecosystems. Zoology is one ... and paleontologist. Van Beneden elucidated, together with Walther Flemming and Eduard Strasburger, the essential facts of mitosis, where, in contrast to meiosis, there is a qualitative and quantitative equality of chromosome distribution to daughter cells. (See karyotype). Publications * ''Rech ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilhelm Von Waldeyer-Hartz
Heinrich Wilhelm Gottfried von Waldeyer-Hartz (6 October 1836 – 23 January 1921) was a German anatomist, known for summarizing neuron theory and for naming the chromosome. He is also remembered by anatomical structures of the human body which were named after him: Waldeyer's tonsillar ring (the lymphoid tissue ring of the naso- and oropharynx) and Waldeyer's glands (of the eyelids). Contribution to neuron theory Waldeyer's name is associated in neuroscience with the " neuron theory", and for coining the term "neuron" to describe the basic structural unit of the nervous system. Waldeyer synthesized the discoveries by neuroanatomists (and later Nobel Prize winners) Camillo Golgi (1843–1926) and Santiago Ramón y Cajal (1852–1934), who had used the silver nitrate method of staining nerve tissue (Golgi's method), to formulate widely cited reviews of the theory. Waldeyer learned Spanish in order to absorb Cajal's detailed studies using Golgi's method and became his friend, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosome
A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most important of these proteins are the histones. Aided by chaperone proteins, the histones bind to and condense the DNA molecule to maintain its integrity. These eukaryotic chromosomes display a complex three-dimensional structure that has a significant role in transcriptional regulation. Normally, chromosomes are visible under a light microscope only during the metaphase of cell division, where all chromosomes are aligned in the center of the cell in their condensed form. Before this stage occurs, each chromosome is duplicated ( S phase), and the two copies are joined by a centromere—resulting in either an X-shaped structure if the centromere is located equatorially, or a two-armed structure if the centromere is located distally; the jo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Nucleus
The cell nucleus (; : nuclei) is a membrane-bound organelle found in eukaryote, eukaryotic cell (biology), cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have #Anucleated_cells, no nuclei, and a few others including osteoclasts have Multinucleate, many. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm; and the nuclear matrix, a network within the nucleus that adds mechanical support. The cell nucleus contains nearly all of the cell's genome. Nuclear DNA is often organized into multiple chromosomes – long strands of DNA dotted with various proteins, such as histones, that protect and organize the DNA. The genes within these chromosomes are Nuclear organization, structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basophilic
Basophilic is a technical term used by pathologists. It describes the appearance of cells, tissues and cellular structures as seen through the microscope after a histological section has been stained with a basic dye. The most common such dye is haematoxylin. The name basophilic refers to the characteristic of these structures to be stained very well by basic dyes. This can be explained by their charges. Basic dyes are cationic, i.e. contain positive charges, and thus they stain anionic structures (i.e. structures containing negative charges), such as the phosphate backbone of DNA in the cell nucleus and ribosomes. "Basophils" are cells that "love" (from greek "-phil") basic dyes, for example haematoxylin, azure and methylene blue. Specifically, this term refers to: * basophil granulocytes * anterior pituitary basophils An abnormal increase in basophil granulocytes is therefore also described as basophilia."Basophilia" ''Collins Online Dictionary'' 2024 https://www.colli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
