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Walter M. Fitch
Walter Monroe Fitch (May 21, 1929 – March 10, 2011) was a pioneering American researcher in molecular evolution. Education and career Fitch attended University of California, Berkeley, where he graduated with an A.B. in chemistry in 1953 and a Ph.D. in comparative biochemistry in 1958. Fitch spent 24 years at the University of Wisconsin–Madison, followed by three years at the University of Southern California and then was professor of molecular evolution at the University of California, Irvine, until his death. He was a member of the National Academy of Sciences, the American Philosophical Society, and the American Association for the Advancement of Science, and was a Foreign Member of the London Linnean Society. He co-founded the journal ''Molecular Biology and Evolution'', with Masatoshi Nei, and was the first president of the Society for Molecular Biology and Evolution. Research Fitch is noted for his pioneering work on reconstruction of phylogenies (evolutionary trees) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
San Diego
San Diego ( , ) is a city on the Pacific coast of Southern California, adjacent to the Mexico–United States border. With a population of over 1.4 million, it is the List of United States cities by population, eighth-most populous city in the United States. San Diego is the county seat, seat of San Diego County. It is known for its mild Mediterranean climate, extensive List of beaches in San Diego County, beaches and List of parks in San Diego, parks, long association with the United States Navy, and recent emergence as a wireless, electronics, List of hospitals in San Diego, healthcare, and biotechnology development center. Historically home to the Kumeyaay people, San Diego has been referred to as the ''Birthplace of California'', as it was the first site visited and settled by Europeans on what is now the West Coast of the United States. In 1542, Juan Rodríguez Cabrillo claimed the area for Spain, forming the basis for the settlement of Alta California, 200 years later. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phylogenetic Tree
A phylogenetic tree or phylogeny is a graphical representation which shows the evolutionary history between a set of species or taxa during a specific time.Felsenstein J. (2004). ''Inferring Phylogenies'' Sinauer Associates: Sunderland, MA. In other words, it is a branching diagram or a tree showing the evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical or genetic characteristics. In evolutionary biology, all life on Earth is theoretically part of a single phylogenetic tree, indicating common ancestry. Phylogenetics is the study of phylogenetic trees. The main challenge is to find a phylogenetic tree representing optimal evolutionary ancestry between a set of species or taxa. Computational phylogenetics (also phylogeny inference) focuses on the algorithms involved in finding optimal phylogenetic tree in the phylogenetic landscape. Phylogenetic trees may be rooted or unrooted. In a ''rooted'' p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Irvine Faculty
A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in the Midd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of The Linnean Society Of London
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses * Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton *Fellows (surname) *Mount Fellows, a mountain in Alaska See also *North Fellows Historic District The North Fellows Historic District is a historic district located in Ottumwa, Iowa, United States. The city experienced a housing boom after World War II. This north side neighborhood of single-family brick homes built between 1945 and 1959 ..., listed on the National Register of Historic Places in Wapello County, Iowa * Justice Fellows (other) {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza Researchers
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, Rhinorrhea, runny nose, sore throat, Myalgia, muscle pain, headache, coughing, and fatigue. These symptoms begin one to four (typically two) days after exposure to the virus and last for about two to eight days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia from the virus or a subsequent bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus: types A, B, C, and D. Aquatic birds are the primary source of influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and influenza C virus (ICV) primarily infect humans, and influenza D vir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Center For Science Education
The National Center for Science Education (NCSE) is a Nonprofit organization, not-for-profit membership organization in the United States whose stated mission is to educate the press and the public on the scientific and educational aspects of controversies surrounding the teaching of evolution and climate change, and to provide information and resources to schools, parents, and other citizens working to keep those topics in public school science education. Based in Oakland, California, it said in 2012 that it had 4,500 members including scientists, teachers, clergy, and citizens of varied religious and political affiliations. The Center opposes the teaching of religion, religious views in science classes in United States, America's Public school (government funded), public schools; it does this through initiatives such as Project Steve. The Center has been called the "leading anti-creationist organization" in the United States. The Center is affiliated with the American Associati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systematic Zoology
Systematics is the study of the diversification of living forms, both past and present, and the relationships among living things through time. Relationships are visualized as evolutionary trees (synonyms: phylogenetic trees, phylogenies). Phylogenies have two components: branching order (showing group relationships, graphically represented in cladograms) and branch length (showing amount of evolution). Phylogenetic trees of species and higher taxa are used to study the evolution of traits (e.g., anatomical or molecular characteristics) and the distribution of organisms (biogeography). Systematics, in other words, is used to understand the evolutionary history of life on Earth. The word systematics is derived from the Latin word of Ancient Greek origin '' systema,'' which means systematic arrangement of organisms. Carl Linnaeus used 'Systema Naturae' as the title of his book. Branches and applications In the study of biological systematics, researchers use the different branch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homology (biology)
In biology, homology is similarity in anatomical structures or genes between organisms of different taxa due to shared ancestry, ''regardless'' of current functional differences. Evolutionary biology explains homologous structures as retained heredity from a common descent, common ancestor after having been subjected to adaptation (biology), adaptive modifications for different purposes as the result of natural selection. The term was first applied to biology in a non-evolutionary context by the anatomist Richard Owen in 1843. Homology was later explained by Charles Darwin's theory of evolution in 1859, but had been observed before this from Aristotle's biology onwards, and it was explicitly analysed by Pierre Belon in 1555. A common example of homologous structures is the forelimbs of vertebrates, where the bat wing development, wings of bats and origin of avian flight, birds, the arms of primates, the front flipper (anatomy), flippers of whales, and the forelegs of quadrupedalis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maximum Parsimony
In phylogenetics and computational phylogenetics, maximum parsimony is an optimality criterion under which the phylogenetic tree that minimizes the total number of character-state changes (or minimizes the cost of differentially weighted character-state changes). Under the maximum-parsimony criterion, the optimal tree will minimize the amount of homoplasy (i.e., convergent evolution, parallel evolution, and evolutionary reversals). In other words, under this criterion, the shortest possible tree that explains the data is considered best. Some of the basic ideas behind maximum parsimony were presented by James S. Farris in 1970 and Walter M. Fitch in 1971. Maximum parsimony is an intuitive and simple criterion, and it is popular for this reason. However, although it is easy to ''score'' a phylogenetic tree (by counting the number of character-state changes), there is no algorithm to quickly ''generate'' the most-parsimonious tree. Instead, the most-parsimonious tree must be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emanuel Margoliash
Emanuel Margoliash (February 10, 1920 – April 10, 2008) was a biochemist who spent much of his career studying the protein cytochrome c. He is best known for his work on molecular evolution; with Walter Fitch, he devised the Fitch-Margoliash method for constructing evolutionary trees based on protein sequences. He was a member of the United States National Academy of Sciences, National Academy of Sciences and the American Academy of Arts and Sciences. Biography Margoliash was born in Cairo in 1920. He earned an M.D. from the American University of Beirut. He served as an Israeli Army medical officer during the 1948 Arab-Israeli War, and subsequently held research positions at the Hebrew University of Jerusalem-Hadassah Medical School, the Nobel Institute Department of Biochemistry, the University of Utah College of Medicine, the McGill-Montreal General Hospital Research Institute, Abbott Laboratories, Northwestern University, where he was chair of the Department of Bioche ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fitch-Margoliash Method
Computational phylogenetics, phylogeny inference, or phylogenetic inference focuses on computational and optimization algorithms, heuristics, and approaches involved in phylogenetic analyses. The goal is to find a phylogenetic tree representing optimal evolutionary ancestry between a set of genes, species, or taxa. Maximum likelihood, parsimony, Bayesian, and minimum evolution are typical optimality criteria used to assess how well a phylogenetic tree topology describes the sequence data. Nearest Neighbour Interchange (NNI), Subtree Prune and Regraft (SPR), and Tree Bisection and Reconnection (TBR), known as tree rearrangements, are deterministic algorithms to search for optimal or the best phylogenetic tree. The space and the landscape of searching for the optimal phylogenetic tree is known as phylogeny search space. Maximum Likelihood (also likelihood) optimality criterion is the process of finding the tree topology along with its branch lengths that provides the highest proba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
