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WAIFW Matrix
In infectious disease modelling, a who acquires infection from whom (WAIFW) matrix is a matrix that describes the rate of transmission of infection between different groups in a population, such as people of different ages. Used with an SIR model, the entries of the WAIFW matrix can be used to calculate the basic reproduction number using the next generation operator approach. Examples The 2 \times 2 WAIFW matrix for two groups is expressed as \begin \beta_ & \beta_ \\ \beta_ & \beta_ \end where \beta_ is the transmission coefficient from an infected member of group i and a susceptible member of group j. Usually specific mixing patterns are assumed. Assortative mixing Assortative mixing occurs when those with certain characteristics are more likely to mix with others with whom they share those characteristics. It could be given by \begin \beta & 0 \\ 0 & \beta \end or the general 2 \times 2 WAIFW matrix so long as \beta_, \beta_ > \beta_, \beta_. Disassortative mixing is ins ...
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Mathematical Modelling In Epidemiology
Mathematical models can project how infectious diseases progress to show the likely outcome of an epidemic (including in plants) and help inform public health and plant health interventions. Models use basic assumptions or collected statistics along with mathematics to find parameters for various infectious diseases and use those parameters to calculate the effects of different interventions, like mass vaccination programs. The modelling can help decide which intervention(s) to avoid and which to trial, or can predict future growth patterns, etc. History The modeling of infectious diseases is a tool that has been used to study the mechanisms by which diseases spread, to predict the future course of an outbreak and to evaluate strategies to control an epidemic. The first scientist who systematically tried to quantify causes of death was John Graunt in his book ''Natural and Political Observations made upon the Bills of Mortality'', in 1662. The bills he studied were listings of nu ...
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Matrix (mathematics)
In mathematics, a matrix (plural matrices) is a rectangular array or table of numbers, symbols, or expressions, arranged in rows and columns, which is used to represent a mathematical object or a property of such an object. For example, \begin1 & 9 & -13 \\20 & 5 & -6 \end is a matrix with two rows and three columns. This is often referred to as a "two by three matrix", a "-matrix", or a matrix of dimension . Without further specifications, matrices represent linear maps, and allow explicit computations in linear algebra. Therefore, the study of matrices is a large part of linear algebra, and most properties and operations of abstract linear algebra can be expressed in terms of matrices. For example, matrix multiplication represents composition of linear maps. Not all matrices are related to linear algebra. This is, in particular, the case in graph theory, of incidence matrices, and adjacency matrices. ''This article focuses on matrices related to linear algebra, an ...
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Compartmental Models In Epidemiology
Compartmental models are a very general modelling technique. They are often applied to the mathematical modelling of infectious diseases. The population is assigned to compartments with labels – for example, S, I, or R, (Susceptible, Infectious, or Recovered). People may progress between compartments. The order of the labels usually shows the flow patterns between the compartments; for example SEIS means susceptible, exposed, infectious, then susceptible again. The origin of such models is the early 20th century, with important works being that of Ross in 1916, Ross and Hudson in 1917, Kermack and McKendrick in 1927 and Kendall in 1956. The Reed-Frost model was also a significant and widely-overlooked ancestor of modern epidemiological modelling approaches. The models are most often run with ordinary differential equations (which are deterministic), but can also be used with a stochastic (random) framework, which is more realistic but much more complicated to analyze. Mod ...
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Basic Reproduction Number
In epidemiology, the basic reproduction number, or basic reproductive number (sometimes called basic reproduction ratio or basic reproductive rate), denoted R_0 (pronounced ''R nought'' or ''R zero''), of an infection is the expected number of cases directly generated by one case in a population where all individuals are susceptible to infection. The definition assumes that no other individuals are infected or immunized (naturally or through vaccination). Some definitions, such as that of the Australian Department of Health, add the absence of "any deliberate intervention in disease transmission". The basic reproduction number is not necessarily the same as the effective reproduction number R (usually written R_t 't'' for time sometimes R_e), which is the number of cases generated in the current state of a population, which does not have to be the uninfected state. R_0 is a dimensionless number (persons infected per person infecting) and not a time rate, which would have u ...
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Next-generation Matrix
In epidemiology, the next-generation matrix is used to derive the basic reproduction number, for a compartmental model of the spread of infectious diseases. In population dynamics it is used to compute the basic reproduction number for structured population models. It is also used in multi-type branching models for analogous computations. The method to compute the basic reproduction ratio using the next-generation matrix is given by Diekmann ''et al.'' (1990) and van den Driessche and Watmough (2002). To calculate the basic reproduction number by using a next-generation matrix, the whole population is divided into n compartments in which there are m infected compartments. Let x_i, i=1,2,3,\ldots,m be the numbers of infected individuals in the i^ infected compartment at time ''t''. Now, the is :
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Royal Statistical Society
The Royal Statistical Society (RSS) is an established statistical society. It has three main roles: a British learned society for statistics, a professional body for statisticians and a charity which promotes statistics for the public good. History The society was founded in 1834 as the Statistical Society of London, though a perhaps unrelated London Statistical Society was in existence at least as early as 1824. At that time there were many provincial statistics societies throughout Britain, but most have not survived. The Manchester Statistical Society (which is older than the LSS) is a notable exception. The associations were formed with the object of gathering information about society. The idea of statistics referred more to political knowledge rather than a series of methods. The members called themselves "statists" and the original aim was "...procuring, arranging and publishing facts to illustrate the condition and prospects of society" and the idea of interpre ...
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Mathematical Modelling Of Infectious Disease
Mathematical models can project how infectious diseases progress to show the likely outcome of an epidemic (including in plants) and help inform public health and plant health interventions. Models use basic assumptions or collected statistics along with mathematics to find parameters for various infectious diseases and use those parameters to calculate the effects of different interventions, like mass vaccination programs. The modelling can help decide which intervention(s) to avoid and which to trial, or can predict future growth patterns, etc. History The modeling of infectious diseases is a tool that has been used to study the mechanisms by which diseases spread, to predict the future course of an outbreak and to evaluate strategies to control an epidemic. The first scientist who systematically tried to quantify causes of death was John Graunt in his book ''Natural and Political Observations made upon the Bills of Mortality'', in 1662. The bills he studied were listings of ...
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Next-generation Matrix
In epidemiology, the next-generation matrix is used to derive the basic reproduction number, for a compartmental model of the spread of infectious diseases. In population dynamics it is used to compute the basic reproduction number for structured population models. It is also used in multi-type branching models for analogous computations. The method to compute the basic reproduction ratio using the next-generation matrix is given by Diekmann ''et al.'' (1990) and van den Driessche and Watmough (2002). To calculate the basic reproduction number by using a next-generation matrix, the whole population is divided into n compartments in which there are m infected compartments. Let x_i, i=1,2,3,\ldots,m be the numbers of infected individuals in the i^ infected compartment at time ''t''. Now, the is :
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Matrices
Matrix most commonly refers to: * ''The Matrix'' (franchise), an American media franchise ** ''The Matrix'', a 1999 science-fiction action film ** "The Matrix", a fictional setting, a virtual reality environment, within ''The Matrix'' (franchise) * Matrix (mathematics), a rectangular array of numbers, symbols or expressions Matrix (or its plural form matrices) may also refer to: Science and mathematics * Matrix (mathematics), algebraic structure, extension of vector into 2 dimensions * Matrix (logic), part of a formula in prenex normal form * Matrix (biology), the material in between a eukaryotic organism's cells * Matrix (chemical analysis), the non-analyte components of a sample * Matrix (geology), the fine-grained material in which larger objects are embedded * Matrix (composite), the constituent of a composite material * Hair matrix, produces hair * Nail matrix, part of the nail in anatomy Arts and entertainment Fictional entities * Matrix (comics), two comic b ...
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Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical t ...
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Mathematical And Theoretical Biology
Mathematical and theoretical biology, or biomathematics, is a branch of biology which employs theoretical analysis, mathematical models and abstractions of the living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of experiments to prove and validate the scientific theories. The field is sometimes called mathematical biology or biomathematics to stress the mathematical side, or theoretical biology to stress the biological side. Theoretical biology focuses more on the development of theoretical principles for biology while mathematical biology focuses on the use of mathematical tools to study biological systems, even though the two terms are sometimes interchanged. Mathematical biology aims at the mathematical representation and modeling of biological processes, using techniques and tools of applied mathematics. It can be useful in both theoretical and pra ...
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