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Vobtusine
Vobtusine is an alkaloid found in several different plants in the genus ''Voacanga''. See also *Apparicine * Affinisine *Voacamine *Lochnericine Lochnericine is a major monoterpene indole alkaloid present in the roots of '' Catharanthus roseus''. It is also present in '' Tabernaemontana divaricata''. Chemistry Synthesis Lochnericine is formed from stereoselective epoxidation of carbo ... References {{Reflist Indole alkaloids Alkaloids found in Apocynaceae ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voacamine
Voacamine, also known under the older names voacanginine and vocamine, is a naturally occurring dimeric indole alkaloid of the secologanin type, found in a number of plants, including ''Voacanga africana'' and ''Tabernaemontana divaricata''. It is approved for use as an antimalarial drug in several African countries. Voacamine exhibits cannabinoid CB1 receptor antagonistic activity. Chemistry Structure There is considerable confusion about the absolute stereochemical configuration of voacamine and the originally published absolute structure had to be later revised. It has an ibogaine unit joined with vobasine unit. Adverse Effect Voacamine can cause hypertension in high dose. See also * Vincamine Vincamine is a monoterpenoid indole alkaloid found in the leaves of ''Vinca minor'' (lesser periwinkle), comprising about 25-65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids. Uses Vincamine is sold in Eu ... * Vobtusine References {{ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a class of basic BASIC (Beginners' All-purpose Symbolic Instruction Code) is a family of general-purpose, high-level programming languages designed for ease of use. The original version was created by John G. Kemeny and Thomas E. Kurtz at Dartmouth College ..., natural product, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms includi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voacanga
''Voacanga'' is a genus of plants in the family Apocynaceae found in Africa, Southeast Asia, New Guinea, and Australia. the World Checklist of Selected Plant Families recognises 13 species:Search for "Voacanga", ;Species # ''Voacanga africana'' Stapf ex Scott-Elliot - tropical W + C + E + S Africa # '' Voacanga bracteata'' Stapf - tropical W + C Africa # '' Voacanga caudiflora'' Stapf - tropical W Africa # '' Voacanga chalotiana'' Pierre ex Stapf - tropical C Africa # '' Voacanga foetida'' ( Blume) Rolfe -Java, Borneo, Sumatra, Philippines # '' Voacanga globosa'' ( Blanco) Merr. - Philippines # '' Voacanga gracilipes'' (Miq.) Markgr. - Maluku # '' Voacanga grandifolia'' (Miq.) Rolfe - Indonesia, Philippines, New Guinea, Queensland # '' Voacanga havilandii'' Ridl. - Sarawak # '' Voacanga megacarpa'' Merr. - Philippines # '' Voacanga pachyceras'' Leeuwenb. - Zaïre # '' Voacanga psilocalyx'' Pierre ex Stapf - Nigeria, Cameroon, Gabon, Republic of Congo # '' Voacanga thoua ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apparicine
Apparicine is a monoterpenoid indole alkaloid. It is named after Apparicio Duarte, a Brazilian botanist who studied the ''Aspidosperma'' species from which apparicine was first isolated. It was the first member of the vallesamine group of alkaloids to be isolated and have its structure established, which was first published in 1965. It has also been known by the synonyms gomezine, pericalline, and tabernoschizine. Biochemistry The alkaloid has been isolated from seven species of ''Aspidosperma''. It is the principal alkaloid found in the callus of ''Tabernaemontana elegans'', and has also been identified in other ''Tabernaemontana'' species, including '' T. africana'', '' T. divaricata'', '' T. orientalis'', and '' T. pachysiphon''. In studies of ''T. pachysiphon'', it was found that alkaloid content including that of apparicine was greatest in young leaves and leaves receiving greater shade, and varied with leaf age, plant age, and provenance. Research on '' Aspidosperma pyr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Affinisine
Affinisine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus ''Tabernaemontana''. Structurally, it can be considered a member of the sarpagine alkaloid family and may be synthesized from tryptophan via a Pictet-Spengler reaction. Pharmacology Limited pharmacological testing has indicated that affinisine may effectively inhibit acetylcholinesterase and butyrylcholinesterase. See also * Affinine Affinine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus ''Tabernaemontana''. Structurally it can be considered a member of the vobasine alkaloid family and may be synthesized from tryptophan. Limited pharmacolog ... * 19-Epivoacristine References Acetylcholinesterase inhibitors Quinolizidine alkaloids Indoles {{alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lochnericine
Lochnericine is a major monoterpene indole alkaloid present in the roots of '' Catharanthus roseus''. It is also present in '' Tabernaemontana divaricata''. Chemistry Synthesis Lochnericine is formed from stereoselective epoxidation of carbons 6 and 7 of tabersonine. Derivatives See also * Pericine * Pervine * Tabersonine * Vincamine References {{Reflist Indole alkaloids Alkaloids found in Apocynaceae ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indole Alkaloids
Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids. Containing more than 4100 known different compounds, it is one of the largest classes of alkaloids. Many of them possess significant physiological activity and some of them are used in medicine. The amino acid tryptophan is the biochemical precursor of indole alkaloids. History The action of some indole alkaloids has been known for ages. Aztecs used the psilocybin mushrooms which contain alkaloids psilocybin and psilocin. The flowering plant ''Rauvolfia serpentina'' which contains reserpine was a common medicine in India around 1000 BC. Africans used the roots of the perennial rainforest shrub Iboga, which contain ibogaine, as a stimulant. An infusion of Calabar bean seeds was given to people accused of crime in Nigeria: its rejection by stomach was regarded as a sign of innoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
