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Virilized
Virilization or masculinization is the biological development of adult male characteristics in young males or females. Most of the changes of virilization are produced by androgens. Virilization is a medical term commonly used in three medical and biology of sex contexts: prenatal biological sexual differentiation, the postnatal changes of typical chromosomal male (46, XY) puberty, and excessive androgen effects in typical chromosomal females (46, XX). It is also the intended result of androgen replacement therapy in males with delayed puberty and low testosterone. Prenatal virilization In the prenatal period, virilization refers to closure of the perineum, thinning and wrinkling (rugation) of the scrotum, growth of the penis, and closure of the urethral groove to the tip of the penis. In this context, ''masculinization'' is synonymous with ''virilization''. Prenatal virilization of XX fetuses and undervirilization of XY fetuses are common causes of ambiguous genitalia such as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androgen
An androgen (from Greek ''andr-'', the stem of the word meaning ) is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes the embryological development of the primary male sex organs, and the development of male secondary sex characteristics at puberty. Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. The major androgen in males is testosterone. Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development. DHT ''in utero'' causes differentiation of the penis, scrotum and prostate. In adulthood, DHT contributes to balding, prostate growth, and sebaceous gland activity. Although androgens are commonly thought of only as male Sex steroids, sex hormones, females also have them, but at lower levels: they function in libido and sexual arousal. An ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Y Chromosome
The Y chromosome is one of two sex chromosomes in therian mammals and other organisms. Along with the X chromosome, it is part of the XY sex-determination system, in which the Y is the sex-determining chromosome because the presence of the Y chromosome causes offspring produced in sexual reproduction to be of male sex. In mammals, the Y chromosome contains the SRY gene, which triggers development of male gonads. The Y chromosome is passed only from male parents to male offspring. Overview Discovery The Y chromosome was identified as a sex-determining chromosome by Nettie Stevens at Bryn Mawr College in 1905 during a study of the mealworm ''Tenebrio molitor''. Edmund Beecher Wilson independently discovered the same mechanisms the same year, working with Hemiptera. Stevens proposed that chromosomes always existed in pairs and that the smaller chromosome (now labelled "Y") was the pair of the X chromosome discovered in 1890 by Hermann Henking. She realized that th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pubic Hair
Pubic hair (or pubes , ) is terminal hair, terminal body hair that is found in the sex organ, genital area and pubic region of adolescent and adult humans. The hair is located on and around the sex organs, and sometimes at the top of the inside of the thighs, even extending down the perineum, and to the Anus, anal region. Pubic hair is also found on the scrotum and base of the Body of penis, penile shaft (in males) and on the vulva (in females). Around the Pubis (bone), pubis bone and the mons pubis that covers it, it is known as a ''pubic patch'', which can be styled. Although fine vellus hair is present in the area during childhood, pubic hair is considered to be the heavier, longer, coarser hair that develops during puberty as an effect of rising levels of hormones: androgens in males and estrogens in females. Many cultures regard pubic hair as erotic, and most cultures associate it with the genitals, which people are expected to keep covered at all times. In some cultures ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voice Change
A voice change or voice mutation, sometimes referred to as a voice break or voice crack, commonly refers to the deepening of the voice of men as they reach puberty. Before puberty both sexes have roughly similar vocal pitches, but during puberty the male voice typically deepens an octave, while the female voice usually deepens only by a few tones. A similar effect is a "voice crack", during which a person's voice suddenly and unintentionally enters a higher register (usually falsetto) for a brief period of time. This may be caused by singing or talking at a pitch outside the person's natural vocal range, stress, fatigue, emotional tension, or the physical changes associated with puberty. An instance of a voice crack (when associated with puberty) lasts for only a moment and generally occurs less frequently as a person grows into maturity. Anatomical changes Most of the voice change begins around puberty. Adult pitch is reached 2–3 years later, but the voice does not stabi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pubarche
Pubarche () refers to the first appearance of pubic hair at puberty. It is one of the earliest physical changes of puberty and can occur independently of complete puberty. It is usually the second sign of puberty, after thelarche in females and gonadarche in males (though in females, it can also happen before thelarche, but this is less common). The early stage of sexual maturation, also known as adrenarche, is marked by characteristics including the development of pubic hair, Underarm hair, axillary hair, Body odor, adult apocrine body odor, acne, and increased oiliness of hair and skin. The Encyclopedia of Child and Adolescent Health corresponds SMR2 (sexual maturity rating) with pubarche, defining it as the development of pubic hair that occurs at a mean age of 11.6 years in females (range 9.3–13.9 years) and 12.6 years in males (range 10.7–14.5 years). It further describes that pubarche's physical manifestation is Vellus hair, vellus hair over the labia or the base of the pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
5 Alpha Reductase Deficiency
5 (five) is a number, numeral and digit. It is the natural number, and cardinal number, following 4 and preceding 6, and is a prime number. Humans, and many other animals, have 5 digits on their limbs. Mathematics 5 is a Fermat prime, a Mersenne prime exponent, as well as a Fibonacci number. 5 is the first congruent number, as well as the length of the hypotenuse of the smallest integer-sided right triangle, making part of the smallest Pythagorean triple ( 3, 4, 5). 5 is the first safe prime and the first good prime. 11 forms the first pair of sexy primes with 5. 5 is the second Fermat prime, of a total of five known Fermat primes. 5 is also the first of three known Wilson primes (5, 13, 563). Geometry A shape with five sides is called a pentagon. The pentagon is the first regular polygon that does not tile the plane with copies of itself. It is the largest face any of the five regular three-dimensional regular Platonic solid can have. A conic is determined ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androgen Insensitivity Syndrome
Androgen insensitivity syndrome (AIS) is a condition involving the inability to respond to androgens, typically due to androgen receptor dysfunction. It affects 1 in 20,000 to 64,000 XY (karyotype, karyotypically male) births. The condition results in the partial or complete inability of Animal cell, cells to respond to androgens. This unresponsiveness can impair or prevent the Development of the reproductive system, development of male genitals, as well as impairing or preventing the development of male Secondary sex characteristics, secondary sexual characteristics at puberty. It does not significantly impair female genital or sexual development. The insensitivity to androgens is therefore clinically significant only when it occurs in genetic males, (i.e. individuals with a Y chromosome, Y-chromosome, or more specifically, an SRY, SRY gene). Clinical phenotypes in these individuals range from a typical body shape, male habitus with mild spermatogenesis, spermatogenic defect or re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Progestin-induced Virilisation
Maternal use of androgens or high doses of certain weakly androgenic synthetic progestogens (progestins) structurally related to testosterone can masculinize (virilize) the vulva of a female fetus during susceptible times in pregnancy. Some degree of fusion of the labioscrotal folds and urogenital folds and clitoral enlargement can occur if exposure occurs from the 8th through the 12th week of gestation, but only clitoral enlargement can occur if exposure occurs after the 12th week. This can in some cases result in ambiguous genitalia. Fetal masculinization of the vulva is usually due to enzyme abnormalities involved in adrenal steroid biosynthesis, resulting in congenital adrenal hyperplasia (CAH); fetal masculinization of the vulva is much less frequently due to maternal use of androgenic steroids. Fetal masculinization of the vulva due to maternal use of androgenic steroids is generally less advanced than that due to CAH, and unlike CAH, does not cause progressive viriliz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clitoromegaly
Clitoromegaly (or macroclitoris) is an abnormal enlargement of the clitoris that is mostly congenital; it is otherwise acquired through deliberately induced clitoral enlargement, a form of body modification, by use of anabolic steroids, in particular testosterone. It can happen as part of a gender transition. It is clinically distinguishable from normal enlargement of the clitoris seen during sexual arousal. Presentation Degree of genital ambiguity is commonly measured by the Prader classification, which ranges, in ascending order of masculinisation, from 1: ''female external genitalia with clitoromegaly'' through 5: ''pseudo-phallus looking like normal male external genitalia''. Causes Clitoromegaly is a rare condition and can be either present by birth or acquired later in life. If present at birth, congenital adrenal hyperplasia Congenital adrenal hyperplasia (CAH) is a group of Genetic disorder#Autosomal recessive, autosomal recessive disorders characterized by impaired ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenal Gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer adrenal cortex, cortex which produces steroid hormones and an inner Adrenal medulla, medulla. The adrenal cortex itself is divided into three main zones: the zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces three main types of steroid hormones: mineralocorticoids, glucocorticoids, and androgens. Mineralocorticoids (such as aldosterone) produced in the zona glomerulosa help in the regulation of blood pressure and osmoregulation, electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Male
Male (Planet symbols, symbol: ♂) is the sex of an organism that produces the gamete (sex cell) known as sperm, which fuses with the larger female gamete, or Egg cell, ovum, in the process of fertilisation. A male organism cannot sexual reproduction, reproduce sexually without access to at least one ovum from a female, but some organisms can reproduce both sexually and Asexual reproduction, asexually. Most male mammals, including male humans, have a Y chromosome, which codes for the production of larger amounts of testosterone to develop male reproductive organs. In humans, the word ''male'' can also be used to refer to gender, in the social sense of gender role or gender identity. Overview The existence of separate sexes has evolved independently at different times and in different lineage (evolution), lineages, an example of convergent evolution. The repeated pattern is sexual reproduction in isogamy, isogamous species with two or more mating types with gametes of identic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Defeminization
In developmental biology and zoology Zoology ( , ) is the scientific study of animals. Its studies include the anatomy, structure, embryology, Biological classification, classification, Ethology, habits, and distribution of all animals, both living and extinction, extinct, and ..., defeminization is an aspect of the process of sexual differentiation by which a potential female-specific structure, function, or behavior is changed by one of the processes of male development. See also * Sexual differentiation * Defeminization and masculinization * Virilization * Feminization References {{Reflist Sexual anatomy Zoology Physiology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
