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Vincent L. Pecoraro
Vincent L. Pecoraro, professor at the University of Michigan, is a researcher in bioinorganic chemistry and inorganic chemistry. He is a specialist in the chemistry and biochemistry of manganese, vanadium, and metallacrown chemistry. He is a fellow of the American Association for the Advancement of Science Biography Pecoraro was born in Freeport, NY in August 1956; shortly after, his family relocated to California where he spent the majority of his childhood. On completing high school, he continued his education at the University of California, Los Angeles graduating with his B.S. in biochemistry in 1977 and pursued his Ph.D. in chemistry at the University of California, Berkeley working under Ken Raymond. After gaining his Ph.D., he worked with W. Wallace Cleland at the University of Wisconsin-Madison for a three-year post-doc. In 1984, he was appointed assistant professor in the University of Michigan Department of Chemistry. Scientific Achievements Metall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vincent L
Vincent (Latin: ''Vincentius'') is a masculine given name originating from the Roman name ''Vincentius'', which itself comes from the Latin verb ''vincere'', meaning "to conquer." People with the given name Artists *Vincent Apap (1909–2003), Maltese sculptor *Vincent van Gogh (1853–1890), Dutch Post-Impressionist painter *Vincent Munier (born 1976), French wildlife photographer Saints *Vincent of Saragossa (died 304), deacon and martyr, patron saint of Lisbon and Valencia *Vincent, Orontius, and Victor (died 305), martyrs who evangelized in the Pyrenees * Vincent of Digne (died 379), French bishop of Digne *Vincent of Lérins (died 445), Church father, Gallic author of early Christian writings *Vincent Madelgarius (died 677), Benedictine monk who established two monasteries in France *Vincent Ferrer (1350–1419), Valencian Dominican missionary and logician *Vincent de Paul (1581–1660), Catholic priest who served the poor *Vicente Liem de la Paz (Vincent Liem the Nguye ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Imaging
Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organ (anatomy), organs and Tissue (biology), tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging. Measurement and recording techniques that are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), electrocardiography (ECG), and others, represent other technologies that produce data susceptible to representation as a parameter graph versus time or maps that contain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thermodynamic
Thermodynamics is a branch of physics that deals with heat, work, and temperature, and their relation to energy, entropy, and the physical properties of matter and radiation. The behavior of these quantities is governed by the four laws of thermodynamics, which convey a quantitative description using measurable macroscopic physical quantities but may be explained in terms of microscopic constituents by statistical mechanics. Thermodynamics applies to various topics in science and engineering, especially physical chemistry, biochemistry, chemical engineering, and mechanical engineering, as well as other complex fields such as meteorology. Historically, thermodynamics developed out of a desire to increase the efficiency of early steam engines, particularly through the work of French physicist Sadi Carnot (1824) who believed that engine efficiency was the key that could help France win the Napoleonic Wars. Scots-Irish physicist Lord Kelvin was the first to formulate a concise d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hydrogen Atom Abstraction
In chemistry, hydrogen atom abstraction, or hydrogen atom transfer (HAT), refers to a class of chemical reactions where a hydrogen free radical (a neutral hydrogen atom) is removed from a substrate with another molecule. This process follows the general equation: :X^\bullet + H-Y -> X-H + Y^\bullet HAT reactions are common in various redox reactions, hydrocarbon combustion, and interactions involving cytochrome P450 that contain an Fe(V)O unit. The entity removing the hydrogen atom, known as the abstractor (), is often a radical itself, though in some instances, it may be a species with a closed electron shell, such as chromyl chloride. Hydrogen atom transfer can occur via a mechanism known as proton-coupled electron transfer. An illustrative synthetic instance of HAT is observed in iron zeolites Zeolites are a group of several Microporous material, microporous, crystalline aluminosilicate minerals commonly used as commercial adsorption, adsorbents and Catalysis, catalysts. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Photosynthesis
Photosynthesis ( ) is a system of biological processes by which photosynthetic organisms, such as most plants, algae, and cyanobacteria, convert light energy, typically from sunlight, into the chemical energy necessary to fuel their metabolism. ''Photosynthesis'' usually refers to oxygenic photosynthesis, a process that produces oxygen. Photosynthetic organisms store the chemical energy so produced within intracellular organic compounds (compounds containing carbon) like sugars, glycogen, cellulose and starches. To use this stored chemical energy, an organism's cells metabolize the organic compounds through cellular respiration. Photosynthesis plays a critical role in producing and maintaining the oxygen content of the Earth's atmosphere, and it supplies most of the biological energy necessary for complex life on Earth. Some bacteria also perform anoxygenic photosynthesis, which uses bacteriochlorophyll to split hydrogen sulfide as a reductant instead of water, p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxidation
Redox ( , , reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change. Oxidation is the loss of electrons or an increase in the oxidation state, while reduction is the gain of electrons or a decrease in the oxidation state. The oxidation and reduction processes occur simultaneously in the chemical reaction. There are two classes of redox reactions: * Electron-transfer – Only one (usually) electron flows from the atom, ion, or molecule being oxidized to the atom, ion, or molecule that is reduced. This type of redox reaction is often discussed in terms of redox couples and electrode potentials. * Atom transfer – An atom transfers from one substrate to another. For example, in the rusting of iron, the oxidation state of iron atoms increases as the iron converts to an oxide, and simultaneously, the oxidation state of oxygen decreases as it accepts electrons released by the iron. Although oxidati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxygen Evolving Complex
The oxygen-evolving complex (OEC), also known as the water-splitting complex, is a water-oxidizing enzyme involved in the photo-oxidation of water during the light reactions of photosynthesis. OEC is surrounded by 4 core proteins of photosystem II at the membrane-lumen interface. The mechanism for splitting water involves absorption of three photons before the fourth provides sufficient energy for water oxidation. Based on a widely accepted theory from 1970 by Kok, the complex can exist in 5 states, denoted S0 to S4, with S0 the most reduced and S4 the most oxidized. Energy from the photons captured by photosystem II moves the system from state S0 to S1 to S2 to S3 and finally to S4. S4 reacts with water producing free oxygen: : This conversion resets the catalyst to the S0 state. The active site of the OEC consists of a cluster of manganese and calcium Calcium is a chemical element; it has symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catalase
Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals) which catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a very important enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS). Catalase has one of the highest turnover numbers of all enzymes; one catalase molecule can convert millions of hydrogen peroxide molecules to water and oxygen each second. Catalase is a tetramer of four polypeptide chains, each over 500 amino acids long. It contains four iron-containing heme groups that allow the enzyme to react with hydrogen peroxide. The optimum pH for human catalase is approximately 7, and has a fairly broad maximum: the rate of reaction does not change appreciably between pH 6.8 and 7.5. The pH optimum for other catalases varies between 4 and 11 depending on the species. The optimum temperature also varies by species. Structure Human catalase for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Superoxide Dismutase
Superoxide dismutase (SOD, ) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide () anion radical into normal molecular oxygen (O2) and hydrogen peroxide (). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is '' Lactobacillus plantarum'' and related lactobacilli, which use intracellular manganese to prevent damage from reactive . Chemical reaction SODs catalyze the disproportionation of superoxide: : + → + In this way, is converted into two less damaging species. The general form, applicable to all the different metal−coordinated forms of SOD, can be written as follows: * + → + * + + → + The reactions by which SOD−catalyzed dismutation of superoxide for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anti-oxidant
Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals. Autoxidation leads to degradation of organic compounds, including living matter. Antioxidants are frequently added to industrial products, such as polymers, fuels, and lubricants, to extend their usable lifetimes. Foods are also treated with antioxidants to prevent spoilage, in particular the rancidification of oils and fats. In cells, antioxidants such as glutathione, mycothiol, or bacillithiol, and enzyme systems like superoxide dismutase, inhibit damage from oxidative stress. Known dietary antioxidants are vitamins A, C, and E, but the term has also been applied to various compounds that exhibit antioxidant properties in vitro, having little evidence for antioxidant properties in vivo. Dietary supplements marketed as antioxidants have not been shown to maintain health or prevent disease in humans. History As part of their adaptation from marine life, terrestrial plan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include Ribozyme, catalytic RNA molecules, also called ribozymes. They are sometimes descr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PDB 7cat EBI
PDB or pdb may refer to: Organizations * Party of German-speaking Belgians (German: '), a former Belgian political party * Promised Day Brigade, a former Iraqi organization Science and technology * Protein Data Bank, a biological molecule database ** Protein Data Bank (file format) * Potato dextrose broth, a microbiological growth medium * Pee Dee Belemnite, a reference standard for isotopes; see ''δ''13C Computing * PDB (Palm OS), a record database format * Pluggable database, in Oracle Database * Program database, a debugging information format * Python Debugger (pdb), of the Python programming language; see Stepping Other uses * Chess Problem Database Server (PDB Server), a repository for chess problems * Pousette-Dart Band, an American band * President's Daily Brief, a US intelligence document See also * 1,4-Dichlorobenzene or ''para''-dichlorobenzene (PDCB), a chemical * Bangladesh Power Development Board The Bangladesh Power Development Board (BPDB) is a governme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
