Uwe Marx
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Uwe Marx
Uwe Marx (born 26 June 1964) is a German physician and biotechnologist, and one of the world’s leading researchers in the fields of organ-on-a-chip technology and antibody production. Academic Education He gained his qualification as a medical doctor with a specialization in biochemistry in 1988 and his MD in 1991 at Charité – Universitätsmedizin Berlin (a joint medical faculty of the Humboldt University and Free University Berlin) with his thesis on Human Monoclonal Antibodies. Professional Academic Positions Uwe Marx was the head of the Department of Immunobiotechnology at the Institute of Medical Immunology, Charite – Universitätsmedizin Berlin between 1991 and 1995. He was the head of the Department of Medical Biotechnology at the Institute of Immunology and Transfusion Medicine, University of Leipzig between 1995 and 2000. He was the head of the GO-Bio Multi-Organ Chip Program “Multi-organ-bioreactors for the predictive substance testing in chip format,” ...
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Organ-on-a-chip
An organ-on-a-chip (OOC) is a multi-channel 3D microfluidic cell culture, integrated circuit (chip) that simulates the activities, mechanics and physiological response of an entire organ or an organ system. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context. By acting as a more sophisticated ''in vitro'' approximation of complex tissues than standard cell culture, they provide the potential as an alternative to animal models for drug development and toxin testing. Although multiple publications claim to have translated organ functions onto this interface, the development of these microfluidic applications is still in its infancy. Organs-on-chips vary in design and approach between different researchers. Organs that have been simulated by microfluidic devices include brain, lung, heart, kidney, ...
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Antibody
An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as pathogenic bacteria, bacteria and viruses, including those that cause disease. Each individual antibody recognizes one or more specific antigens, and antigens of virtually any size and chemical composition can be recognized. Antigen literally means "antibody generator", as it is the presence of an antigen that drives the formation of an antigen-specific antibody. Each of the branching chains comprising the "Y" of an antibody contains a paratope that specifically binds to one particular epitope on an antigen, allowing the two molecules to bind together with precision. Using this mechanism, antibodies can effectively "tag" the antigen (or a microbe or an infected cell bearing such an antigen) for attack by cells of the immune system, or can neutralize it directly (for example, by blocking a p ...
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Humane World For Animals
Humane World for Animals, formerly the Humane Society of the United States (HSUS) and Humane Society International (HSI), is a global nonprofit organization that focuses on animal welfare and opposes animal-related cruelties of national scope. It uses strategies that are beyond the abilities of local organizations. It works on issues including pets, wildlife, farm animals, horses and other Equus (genus), equines, and animals used in research, Animal testing, testing and education.Simon M. Shane. (January 14, 2014Interview with Wayne Pacelle, president of HSUS Egg-Cite.com. As of 2001, the group's major campaigns targeted factory farming, hunting, the fur trade, puppy mills, and wildlife abuse. The global offices of Humane World for Animals are based in Washington, D.C., and the organization has offices in six continents. The original organization was founded in 1954 by journalist Fred Myers and Helen Jones, Larry Andrews, Marcia Glaser and Oliver M Evans. In 2013, the ''Chron ...
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Organ Improvisers
Organ and organs may refer to: Biology * Organ (biology), a group of tissues organized to serve a common function * Organ system, a collection of organs that function together to carry out specific functions within the body. Musical instruments * Organ (music), a family of keyboard musical instruments characterized by sustained tone ** Electronic organ, an electronic keyboard instrument ** Hammond organ, an electro-mechanical keyboard instrument ** Pipe organ, a musical instrument that produces sound when pressurized air is driven through a series of pipes ** Fairground organ, an automatic mechanical organ designed to provide loud music in fairground settings ** Street organ, a mobile, automatic mechanical pneumatic organ played by an organ grinder ** Theatre organ, a pipe organ originally designed specifically for imitation of an orchestra *** BBC Theatre Organ, several theatre organs used for popular BBC radio programmes Entertainment * Harry "Snapper" Organs, a fictional ...
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1964 Births
Events January * January 1 – The Federation of Rhodesia and Nyasaland is dissolved. * January 5 – In the first meeting between leaders of the Roman Catholic and Orthodox churches since the fifteenth century, Pope Paul VI and Patriarch Athenagoras I of Constantinople meet in Jerusalem. * January 6 – A British firm, the Leyland Motors, Leyland Motor Corp., announces the sale of 450 buses to the Cuban government, challenging the United States blockade of Cuba. * January 9 – ''Martyrs' Day (Panama), Martyrs' Day'': Armed clashes between United States troops and Panamanian civilians in the Panama Canal Zone precipitate a major international crisis, resulting in the deaths of 21 Panamanians and 4 U.S. soldiers. * January 11 – United States Surgeon General Luther Terry reports that smoking may be hazardous to one's health (the first such statement from the U.S. government). * January 22 – Kenneth Kaunda is inaugurated as the first Prime Minister of Northern Rhodesi ...
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Living People
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German Medical Researchers
German(s) may refer to: * Germany, the country of the Germans and German things **Germania (Roman era) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizenship in Germany, see also German nationality law **Germanic peoples (Roman era) * German diaspora * German language * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (di ...
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