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Uncaria Guianensis
''Uncaria guianensis'', the cat's claw, is a plant species in the genus ''Uncaria'' found in the Amazon biome. Other names for the plant include ''uña de gato'', ''Paraguayo'' and ''vincaria''. ''Uncaria guianensis'' contains many phytochemicals ((-)-epicatechin, alkaloid, beta-Sitosterol, campesterol, campherol, catechol, catechutannic acid, chlorogenic acid, ellagic acid, gallic acid, hyperin, oleanolic acid, rutin, stigmasterol, ursolic acid) and proanthocyanidin B1 and proanthocyanidin B2 Procyanidin B2 is a B type proanthocyanidin. Its structure is (−)-Epicatechin-(4β→8)-(−)-epicatechin. Procyanidin B2 can be found in ''Cinchona pubescens'' (Chinchona: in the rind, bark, and cortex), in '' Cinnamomum verum'' (Ceylon cinnamo ..., Proanthocyanidin-B2 B type proanthocyanidins, in the root. References |
Jean Baptiste Christophore Fusée Aublet
Jean Baptiste Christophore Fusée Aublet (November 4, 1720 – May 6, 1778) was a French pharmacist, botanist and one of the earliest botanical explorers in South America.JSTOR He was one of the first botanists to study ethnobotany in the Neotropics. Born in Salon-de-Provence, Aublet left home early and traveled to Grenada, then a French colony, where he became an apothecary's assistant and learned about medicinal plants. A year later he returned to France and continued his studies in natural history, chemistry, and pharmacology. One of his mentors was Bernard de Jussieu, a French naturalist who would later help him with plant identification.Mori He joined the French East India Company and in 1752 was sent to Mauritius (then known as ''l'Île de France'') to establish a pharmacy and a botanical garden. He became involved in an intense rivalry with Pierre Poivre, a fellow botanist at the Mon Plaisir garden, and eventually left to establish a new garden at Le Réduit. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ellagic Acid
Ellagic acid is a polyphenol found in numerous fruits and vegetables. It is the dilactone of hexahydroxydiphenic acid. Name The name comes from the French term ''acide ellagique'', from the word ''galle'' spelled backwards because it can be obtained from ''noix de galle'' (galls), and to distinguish it from ''acide gallique'' (gallic acid). The molecule structure resembles to that of two gallic acid molecules being assembled "head to tail" and bound together by a C–C bond (as in biphenyl, or in diphenic acid) and two lactone links (cyclic carboxylic esters). Metabolism Biosynthesis Plants produce ellagic acid from hydrolysis of tannins such as ellagitannin and geraniin. Biodegradation Urolithins are gut flora human metabolites of dietary ellagic acid derivatives. Ellagic acid has low bioavailability, with 90% remaining unabsorbed from the intestines until metabolized by microflora to the more bioavailable urolintins. History Ellagic acid was first discovered b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proanthocyanidin B1
Procyanidin B1 is a procyanidin dimer. It is a molecule with a 4→8 bond (epicatechin-(4β→8)-catechin). Proanthocyanidin-B1 can be found in ''Cinnamomum verum'' (Ceylon cinnamon, in the rind, bark or cortex), in ''Uncaria guianensis'' (cat's claw, in the root), and in ''Vitis vinifera ''Vitis vinifera'', the common grape vine, is a species of flowering plant, native to the Mediterranean Basin, Mediterranean region, Central Europe, and southwestern Asia, from Morocco and Portugal north to southern Germany and east to northern ...'' (common grape vine, in the leaf) or in peach. Procyanidin B1 can be converted into procyanidin A1 by radical oxidation using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals under neutral conditions.Conversion of procyanidin B-type (catechin dimer) to A-type: evidence for abstraction of C-2 hydrogen in catechin during radical oxidation. Kazunari Kondo, Masaaki Kurihara, Kiyoshi Fukuhara, Takashi Tanaka, Takashi Suzuki, Naoki Miyata and Masatake Toy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ursolic Acid
Ursolic acid (sometimes referred to as urson, prunol, malol, or 3β-hydroxyurs-12-en-28-oic acid), is a pentacyclic triterpenoid identified in the epicuticular waxes of apples as early as 1920 and widely found in the peels of fruits, as well as in herbs and spices like rosemary and thyme. Natural occurrence Ursolic acid is present in many plants, such as ''Mirabilis jalapa'', as well as in many fruits and herbs used in daily life (e.g. apples, basil and holy basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, and prunes). Apple peels contain large quantities of ursolic acid and related compounds. Potential biochemical effects A number of potential biochemical effects of ursolic acid have been investigated, but there has been no clinical study demonstrating benefits to human health. ''In vitro'', ursolic acid inhibits the proliferation of various cancer cell types by inhibiting the STAT3 activation pathway, and may als ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stigmasterol
Stigmasterol – a plant sterol (''phytosterol'') – is among the most abundant of plant sterols, having a major function to maintain the structure and physiology of cell membranes. In the European Union, it is a food additive listed with E number E499, and may be used in food manufacturing to increase the phytosterol content, potentially lowering the levels of LDL cholesterol. Discovery Once called ''Wulzen factor'' in the mid-20th century, stigmasterol was discovered by the University of California physiologist Rosalind Wulzen (born 1886). Natural occurrences Stigmasterol is an unsaturated phytosterol occurring in the plant fats or oils of numerous plants, such as soybean, calabar bean, and rape seed, and in herbs used in herbalism practices, including the Chinese herbs '' Ophiopogon japonicus'' (Mai men dong), in ''Mirabilis jalapa''. Stigmasterol is a constituent of various vegetables, legumes, nuts, seeds, and unpasteurized milk. Pasteurization will inactivate st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rutin
Rutin, also called rutoside, quercetin-3-O-rutinoside and sophorin, is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a flavonoid found in a wide variety of plants, including citrus. Occurrences Rutin is one of the phenolic compounds found in the invasive plant species, '' Carpobrotus edulis''. Its name comes from the name of ''Ruta graveolens'', a plant that also contains rutin. Various citrus fruit peels contain 32 to 49 mg/g of flavonoids expressed as rutin equivalents. Citrus leaves contain rutin at concentrations of 11 and 7 g/kg in orange and lime trees, respectively. In 2021, Samoan researchers identified rutin in the native plant, ''matalafi'' ('' Psychotria insularum''). Metabolism The enzyme quercitrinase found in ''Aspergillus flavus'' is in the rutin catabolic pathway. In food Rutin is a citrus flavonoid glycoside found in many plants, including buckwheat, the leaves and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oleanolic Acid
Oleanolic acid or oleanic acid is a naturally occurring pentacyclic triterpenoid related to betulinic acid. It is widely distributed in food and plants where it exists as a free acid or as an aglycone of triterpenoid saponins. Natural occurrence Oleanolic acid can be found in olive oil, ''Phytolacca americana'' (American pokeweed), and ''Syzygium'' spp, garlic, etc. It was first studied and isolated from several plants, including ''Olea europaea'' (leaves, fruit), ''Rosa woodsii'' (leaves), '' Prosopis glandulosa'' (leaves and twigs), '' Phoradendron juniperinum'' (whole plant), ''Syzygium claviflorum'' (leaves), ''Hyptis capitata'' (whole plant), ''Mirabilis jalapa'') and ''Ternstroemia gymnanthera'' (aerial part). Other ''Syzygium'' species including java apple ('' Syzygium samarangense'') and rose apples contain it, as does ''Ocimum tenuiflorum'' (holy basil). Biosynthesis of oleanolic acids Oleanolic acid biosynthesis starts with mevalonate to create squalene. Squalen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperin
Hyperoside is a chemical compound. It is the 3-''O''-galactoside of quercetin. Natural occurrences Hyperoside has been isolated from ''Drosera rotundifolia'', from the Lamiaceae ''Stachys sp.'' and ''Prunella vulgaris'', from ''Rumex acetosella'', '' Cuscuta chinensis'' seeds, from St John's wort and from ''Camptotheca acuminata''. It is one of the phenolic compounds in the invasive plant ''Carpobrotus edulis'' and contributes to the antibacterial properties of the plant. In '' Rheum nobile'' and '' R. rhaponticum'', it serves as a UV blocker found in the bracts. It is also found in ''Geranium niveum'' and ''Taxillus kaempferi ''Taxillus kaempferi'' () is a parasitic plant species in the genus ''Taxillus'' found in China (Anhui, Fujian, W Hubei, S Jiangxi, Sichuan, S Zhejiang), Bhutan and Japan. Its host is ''Pinus thunbergii''.The constituents of Taxillus kaempferi an ...''.The constituents of Taxillus kaempferi and the host, Pinus thunbergii. I. Catechins and flavones of T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gallic Acid
Gallic acid (also known as 3,4,5-trihydroxybenzoic acid) is a trihydroxybenzoic acid with the formula C6 H2( OH)3CO2H. It is classified as a phenolic acid. It is found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants. It is a white solid, although samples are typically brown owing to partial oxidation. Salts and esters of gallic acid are termed "gallates". Isolation and derivatives Gallic acid is easily freed from gallotannins by acidic or alkaline hydrolysis. When heated with concentrated sulfuric acid, gallic acid converts to rufigallol. Hydrolyzable tannins break down on hydrolysis to give gallic acid and glucose or ellagic acid and glucose, known as gallotannins and ellagitannins, respectively. Biosynthesis Gallic acid is formed from 3-dehydroshikimate by the action of the enzyme shikimate dehydrogenase to produce 3,5-didehydroshikimate. This latter compound aromatizes. Reactions Oxidation and oxidative coupling Alkaline solutions ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chlorogenic Acid
Chlorogenic acid (CGA) is the ester of caffeic acid and (−)-quinic acid, functioning as an intermediate in lignin biosynthesis. The term "chlorogenic acids" refers to a related polyphenol family of esters, including hydroxycinnamic acids (caffeic acid, ferulic acid and ''p''-coumaric acid) with quinic acid. Despite the "chloro" of the name, chlorogenic acids contain no chlorine. Instead, the name comes from the Greek χλωρός (khloros, light green) and -γένος (ghenos, a suffix meaning "giving rise to"), pertaining to the green color produced when chlorogenic acids are oxidized. Structural properties Structurally, chlorogenic acid is the ester formed between caffeic acid and the 3-hydroxyl of L-quinic acid. Isomers of chlorogenic acid include the caffeoyl ester at other hydroxyl sites on the quinic acid ring: 4-''O''-caffeoylquinic acid (cryptochlorogenic acid or 4-CQA) and 5-''O''-caffeoylquinic acid (neochlorogenic acid or 5-CQA). The epimer at position 1 has not y ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johann Friedrich Gmelin
Johann Friedrich Gmelin (8 August 1748 – 1 November 1804) was a German natural history, naturalist, botanist, entomologist, herpetologist, and malacologist. Education Johann Friedrich Gmelin was born as the eldest son of Philipp Friedrich Gmelin in 1748 in Tübingen. He studied medicine under his father at University of Tübingen and graduated with a Master's degree in 1768, with a thesis entitled: ', defended under the presidency of Ferdinand Christoph Oetinger, whom he thanks with the words '. Career In 1769, Gmelin became an adjunct professor of medicine at University of Tübingen. In 1773, he became professor of philosophy and adjunct professor of medicine at University of Göttingen. He was promoted to full professor of medicine and professor of chemistry, botany, and mineralogy in 1778. He died in 1804 in Göttingen. Johann Friedrich Gmelin when young became an "apostle" of Carl Linnaeus, probably when Linnaeus was working in the Netherlands, and undertook a plant-c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catechutannic Acid
( or ) is an extract of acacia trees used variously as a food additive, astringent, tannin, and dye. It is extracted from several species of ''Acacia'', but especially ''Senegalia catechu'' (''Acacia catechu''), by boiling the wood in water and evaporating the resulting brew. It is also known as cutch, black cutch, cachou, cashoo, terra Japonica, or Japan earth, and also in Hindi, in Marathi, in Odia, in Assamese and Bengali, and in Malay (hence the Latinized ''Acacia catechu'' chosen as the Linnaean taxonomy name of the type-species Acacia plant which provides the extract). Uses As an astringent it has been used since ancient times in Ayurvedic medicine as well as in breath-freshening spice mixtures—for example in France and Italy it is used in some licorice pastilles. It is also an important ingredient in South Asian cooking paan mixtures, such as ready-made paan masala and gutka. The catechu mixture is high in natural vegetable tannins (which accounts for its astr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
