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Ultrasound Localization Microscopy
Ultrasound Localization Microscopy (ULM) is an advanced ultrasound imaging technique. By localizing microbubbles, ULM overcomes the physical limit of diffraction, achieving sub-wavelength level resolution and qualifying as a super-resolution technique. ULM is primarily utilized in vascular imaging. Because of its deep penetration depth and high resolution, tiny vessels deep within the tissue become visible. This capability gives ULM a significant advantage in diagnosing diseases associated with microvascular development and angiogenesis, such as cancer, diabetes, and certain neurodegenerative diseases. Principle ULM requires multiple image frames that highlight microbubbles (MBs) and approximates the real vasculature by accumulating the located centroids of MBs across the frames. MBs, typically far smaller than the transmitted wavelength, act as point reflectors/emitters of ultrasonic waves, which re-emit waves in a nonlinear fashion. As such, their reflected ultrasound signa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ULM Animation
Ulm () is the sixth-largest city of the southwestern German States of Germany, state of Baden-Württemberg, and with around 129,000 inhabitants, it is Germany's List of cities in Germany by population, 60th-largest city. Ulm is located on the eastern edges of the Swabian Jura mountain range, on the upper course of the River Danube, at the confluence with the small Blau (Danube), Blau Stream, coming from the Blautopf in the west. The mouth of the Iller also falls within Ulm's city limits. The Danube forms the border with Bavaria, where Ulm's twin city Neu-Ulm lies. The city was part of Ulm until 1810, and Ulm and Neu-Ulm have a combined population of around 190,000. Ulm forms an urban district of its own (''Stadtkreis Ulm''), and is the administrative seat of the Alb-Donau-Kreis, the district that surrounds it on three sides, but which the city itself is not a part of. Ulm is the overall 11th-largest List of cities and towns on the river Danube, city on the river Danube, and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contrast-enhanced Ultrasound
Contrast-enhanced ultrasound (CEUS) is the application of ultrasound contrast medium to traditional medical sonography. Ultrasound contrast agents rely on the different ways in which sound waves are reflected from interfaces between substances. This may be the surface of a small air bubble or a more complex structure. Commercially available contrast media are gas-filled microbubbles that are administered intravenously to the systemic circulation. Microbubbles have a high degree of echogenicity (the ability of an object to reflect ultrasound waves). There is a great difference in echogenicity between the gas in the microbubbles and the soft tissue surroundings of the body. Thus, ultrasonic imaging using microbubble contrast agents enhances the ultrasound backscatter, (reflection) of the ultrasound waves, to produce a sonogram with increased contrast due to the high echogenicity difference. Contrast-enhanced ultrasound can be used to image blood perfusion in organs, measure blood ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ultrasound
Ultrasound is sound with frequency, frequencies greater than 20 Hertz, kilohertz. This frequency is the approximate upper audible hearing range, limit of human hearing in healthy young adults. The physical principles of acoustic waves apply to any frequency range, including ultrasound. Ultrasonic devices operate with frequencies from 20 kHz up to several gigahertz. Ultrasound is used in many different fields. Ultrasonic devices are used to detect objects and measure distances. Ultrasound imaging or sonography is often used in medicine. In the nondestructive testing of products and structures, ultrasound is used to detect invisible flaws. Industrially, ultrasound is used for cleaning, mixing, and accelerating chemical processes. Animals such as bats and porpoises use ultrasound for locating prey and obstacles. History Acoustics, the science of sound, starts as far back as Pythagoras in the 6th century BC, who wrote on the mathematical properties of String instrument ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
