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UTRome
UTRome is a database of three-prime untranslated regions in C. elegans developed by Marco Mangone See also * untranslated region (UTR) * UTRdb UTRdb 2.0 is an updated version of the specialized database UTRdb, which focuses on the 5' and 3' untranslated regions (UTRs) of eukaryotic mRNAs. These UTRs play essential roles in the post-transcriptional regulation of gene expression Gene ... * UTRome.org References External links * http://www.UTRome.org Model organism databases RNA Gene expression {{Biodatabase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3'UTR
In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionally influence gene expression. During gene expression, an mRNA molecule is transcribed from the DNA sequence and is later translated into a protein. Several regions of the mRNA molecule are not translated into a protein including the 5' cap, 5' untranslated region, 3′ untranslated region and poly(A) tail. Regulatory regions within the 3′-untranslated region can influence polyadenylation, translation efficiency, localization, and stability of the mRNA. The 3′-UTR contains binding sites for both regulatory proteins and microRNAs (miRNAs). By binding to specific sites within the 3′-UTR, miRNAs can decrease gene expression of various mRNAs by either inhibiting translation or directly causing degradation of the transcript. The 3′-UTR a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Database
In computing, a database is an organized collection of data or a type of data store based on the use of a database management system (DBMS), the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an application associated with the database. Before digital storage and retrieval of data have become widespread, index cards were used for data storage in a wide range of applications and environments: in the home to record and store recipes, shopping lists, contact information and other organizational data; in business to record presentation notes, project research and notes, and contact information; in schools as flash c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caenorhabditis Elegans
''Caenorhabditis elegans'' () is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a Hybrid word, blend of the Greek ''caeno-'' (recent), ''rhabditis'' (rod-like) and Latin ''elegans'' (elegant). In 1900, Émile Maupas, Maupas initially named it ''Rhabditidae, Rhabditides elegans.'' Günther Osche, Osche placed it in the subgenus ''Caenorhabditis'' in 1952, and in 1955, Ellsworth Dougherty, Dougherty raised ''Caenorhabditis'' to the status of genus. ''C. elegans'' is an unsegmented pseudocoelomate and lacks respiratory or circulatory systems. Most of these nematodes are hermaphrodites and a few are males. Males have specialised tails for mating that include spicule (nematode), spicules. In 1963, Sydney Brenner proposed research into ''C. elegans,'' primarily in the area of neuronal development. In 1974, he began research into the molecular biology, molecular and developmental ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marco Mangone
Marco may refer to: People Given name * Marco (actor) (born 1977), South Korean model and actor Surname * Georg Marco (1863–1923), Romanian chess player of German origin * Jindřich Marco (1921–2000), Czechoslovak photographer and numismatist * Joseph Marco (born 1988), Filipino actor * Kenny Marco (1947–2025), Canadian guitarist. * María del Pilar Sinués de Marco (1835–1893), Spanish writer * Tomás Marco (born 1942), Spanish composer and writer on music Places * Marco, Ceará, Brazil, a municipality * Marco, New Zealand, a locality in the Taranaki Region * Marco, Indiana, United States, an unincorporated town * Marco, Missouri, United States, an unincorporated community * Marco Island, Florida, United States, a city and an island Science and technology * Mars Cube One (MarCO), a pair of small satellites which fly by Mars in 2018 * MARCO, a macrophage receptor protein that in humans is encoded by the MARCO gene * Mid-Atlantic Regional Council on the Ocean (MARCO) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Untranslated Region
In molecular genetics, an untranslated region (or UTR) refers to either of two sections, one on each side of a coding sequence on a strand of mRNA. If it is found on the Directionality (molecular biology), 5' side, it is called the Five prime untranslated region, 5' UTR (or leader sequence), or if it is found on the Directionality (molecular biology), 3' side, it is called the Three prime untranslated region, 3' UTR (or trailer sequence). mRNA is RNA that carries information from DNA to the ribosome, the site of protein synthesis (Translation (biology), translation) within a cell. The mRNA is initially Transcription (genetics), transcribed from the corresponding DNA sequence and then translated into protein. However, several regions of the mRNA are usually not translated into protein, including the 5' and 3' UTRs. Although they are called untranslated regions, and do not form the Coding region, protein-coding region of the gene, Upstream open reading frame, uORFs located withi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UTRdb
UTRdb 2.0 is an updated version of the specialized database UTRdb, which focuses on the 5' and 3' untranslated regions (UTRs) of eukaryotic mRNAs. These UTRs play essential roles in the post-transcriptional regulation of gene expression Gene expression is the process (including its Regulation of gene expression, regulation) by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, ... by influencing various processes, including nucleo-cytoplasmic mRNA transport, translation efficiency, subcellular localization, and mRNA stability. Since its launch in 1996, UTRdb has been a valuable resource for researchers studying UTR sequences and their functional implications. Content and features UTRdb 2.0 contains a comprehensive collection of over 26 million entries, derived from more than 6 million genes across 573 species. The database is enriched with a curated set of functional anno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Model Organism Databases
Model organism databases (MODs) are biological databases, or knowledgebases, dedicated to the provision of in-depth biological data for intensively studied model organisms. MODs allow researchers to easily find background information on large sets of genes, efficiently plan experiments, integrate their data with existing knowledge, and formulate new hypotheses . They allow users to analyse results and interpret datasets, and the data they generate are increasingly used to describe less well studied species. Where possible, MODs share common approaches to collect and represent biological information. For example, all MODs use the Gene Ontology (GO) to describe functions, processes and cellular locations of specific gene products. Projects also exist to enable software sharing for curation, visualization and querying between different MODs. Organismal diversity and varying user requirements however mean that MODs are often required to customize capture, display, and provision of dat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
