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UTP6
U3 small nucleolar RNA-associated protein 6 homolog is a protein that in humans is encoded by the ''UTP6'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP11L * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence o ... References Further reading * * * * * * * * * * * {{gene-17-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Small Nucleolar RNA U3
In molecular biology, U3 snoRNA is a non-coding RNA found predominantly in the nucleolus. U3 has C/D box motifs that technically make it a member of the box C/D class of snoRNAs; however, unlike other C/D box snoRNAs, it has not been shown to direct 2'-''O''-methylation of other RNAs. Rather, U3 is thought to guide site-specific cleavage of ribosomal RNA (rRNA) during pre-rRNA processing. The box C/D element is a subset of the six short sequence elements found in all U3 snoRNAs, namely boxes A, A', B, C, C', and D. Secondary Structure The U3 snoRNA secondary structure is characterized by a small 5' domain (with boxes A and A'), and a larger 3' domain (with boxes B, C, C', and D), the two domains being linked by a single-stranded hinge. Boxes B and C form the B/C motif, which appears to be exclusive to U3 snoRNAs, and boxes C' and D form the C'/D motif. The latter is functionally similar to the C/D motifs found in other snoRNAs. The 5' domain and the hinge region act as a pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RCL1
RNA 3'-terminal phosphate cyclase-like protein is an enzyme that in humans is encoded by the ''RCL1'' gene. Copy number variants to the RCL1 gene are associated with a range of neuropsychiatric phenotypes, and a missense variant associated with depression. See also * Fibrillarin * Small nucleolar RNA U3 * RRP9 * UTP6 * UTP11L * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence o ... References Further reading * * * * * * * * * External links * * {{gene-9-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RRP9
U3 small nucleolar RNA-interacting protein 2 is a protein that in humans is encoded by the ''RRP9'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence o ... References Further reading * * * * * * * * * * External links PDBe-KB provides an overview of all the structure information available in the PDB for Human U3 small nucleolar RNA-interacting protein 2 (RRP9) {{gene-3-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UTP11L
Probable U3 small nucleolar RNA-associated protein 11 is a protein that in humans is encoded by the ''UTP11L'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence o ... References Further reading * * * * * * * * * {{gene-1-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UTP14A
U3 small nucleolar RNA-associated protein 14 homolog A is a protein that in humans is encoded by the ''UTP14A'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence o ... References Further reading * * * * * * * * * * {{gene-X-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibrillarin
rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the ''FBL'' gene. Function This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing pre-ribosomal (r)RNA. It is associated with the Small nucleolar RNA U3, U3, U8 small nucleolar RNA, U8, and U13 small nucleolar RNA, U13 small nucleolar RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. Fibrillarin is a component of several ribonucleoproteins including a nucleolar small nuclear ribonucleoprotein (SnRNP) and one of the two classes of snoRNA, sma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
