Trophont
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Trophont
A trophozoite (G. ''trope'', nourishment + ''zoon'', animal) is the activated, feeding stage in the life cycle of certain protozoa such as malaria-causing ''Plasmodium falciparum'' and those of the ''Giardia'' group. The complementary form of the trophozoite state is the thick-walled cyst form. They are often different from the cyst stage, which is a protective, dormant form of the protozoa. Trophozoites are often found in the host's body fluids and tissues and in many cases, they are the form of the protozoan that causes disease in the host. In the protozoan, ''Entamoeba histolytica'' it invades the intestinal mucosa of its host, causing dysentery, which aid in the trophozoites traveling to the liver and leading to the production of hepatic abscesses. Life cycle stages ''Plasmodium falciparium'' The causative organism of malaria is a protozoan, ''Plasmodium falciparium'', that is carried by the female ''Anopheles'' mosquito. Malaria is recorded as the most common disease in ...
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Protozoa
Protozoa (: protozoan or protozoon; alternative plural: protozoans) are a polyphyletic group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic debris. Historically, protozoans were regarded as "one-celled animals". When first introduced by Georg Goldfuss, in 1818, the taxon Protozoa was erected as a class within the Animalia, with the word 'protozoa' meaning "first animals", because they often possess animal-like behaviours, such as motility and predation, and lack a cell wall, as found in plants and many algae. This classification remained widespread in the 19th and early 20th century, and even became elevated to a variety of higher ranks, including phylum, subkingdom, kingdom, and then sometimes included within the paraphyletic Protoctista or Protista. By the 1970s, it became usual to require that all taxa be monophyletic (derived from a common ancestor that would also be regarded as protozo ...
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Merozoite
Apicomplexans, a group of intracellular parasites, have life cycle stages that allow them to survive the wide variety of environments they are exposed to during their complex life cycle. Each stage in the life cycle of an apicomplexan organism is typified by a ''cellular variety'' with a distinct morphology and biochemistry. Not all apicomplexa develop all the following cellular varieties and division methods. This presentation is intended as an outline of a hypothetical generalised apicomplexan organism. Methods of asexual replication Apicomplexans (sporozoans) replicate via ways of multiple fission (also known as schizogony). These ways include , and , although the latter is sometimes referred to as schizogony, despite its general meaning. Merogony is an asexually reproductive process of apicomplexa. After infecting a host cell, a trophozoite ( see glossary below) increases in size while repeatedly replicating its nucleus and other organelles. During this process, the ...
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Balantidiasis
Balantidiasis is a protozoan infection caused by infection with ''Balantidium coli''. History The first study to generate balantidiasis in humans was undertaken by Cassagrandi and Barnagallo in 1896. However, this experiment was not successful in creating an infection and it was unclear whether ''Balantidium coli'' was the actual parasite used. The first case of balantidiasis in the Philippines, where it is the most common, was reported in 1904.Roberts, Larry S., and John Janovy Jr. Gerald D. Schmidt & Larry S. Roberts' Foundations of Parasitology. 8th ed. New York: McGraw-Hill, 2009. Currently, ''Balantidium coli'' is distributed worldwide but less than 1% of the human population is infected.. Pigs are a major reservoir of the parasite, and infection of humans occurs more frequently in areas where pigs commingle with people. This includes places like the Philippines, as previously mentioned, but also includes countries such as Bolivia and Papua New Guinea. Pigs are not the sole s ...
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Balantidium Coli
''Balantidium coli'' is a parasitic species of ciliate Alveolata, alveolates that causes the disease balantidiasis. It is the only member of the ciliate phylum known to be pathogenic to humans, although the main reservoir for this species are mainly domestic and wild pigs. In addition, ''B coli'' is known to infect multiple species of mammal including cattle, camels, sheep, buffalo, and rodents, as well as some birds and marine mammals in rare cases. ''B. coli'' has a world wide distribution, but tends to be spread more in humid and moist environments. Infections in humans are commonly seen in tropical and subtropical countries in central and south America and Asia, although prevalence between each site can vary widely. ''Balantidium coli'' was first describes in the 1857 as ''Paramecium coli'' until being transferred to the genus ''Balantidium'' in 1863. In 2013 after genetic analysis comparing ''B. coli'' with other species in the genus, isolating ''B. coli'' into its own genus ...
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Balantidium LifeCycle
''Balantidium'' is a genus of ciliates. It contains the parasitic species ''Balantidium coli'', the only known cause of balantidiasis. History The first-described species of ''Balantidium'', ''B. entozoon'', was described in 1838 by Christian Gottfried Ehrenberg, Ehrenberg as a member of the genus ''Bursaria (ciliate), Bursaria''. ''Balantidium coli'' observed in patients with dysentery was originally described as ''Paramecium coli'' by Malmstein in 1857. In 1858, René-Édouard Claparède, Edouard Claparède and Johannes Lachmann created the genus ''Balantidium'' and reclassified ''B. entozoon'' as its type species. Stein in 1863, reclassified ''Paramecium coli'' into the genus ''Balantidium''. Transcriptomics Transcriptome data for ''Balantidium ctenopharyngodoni'', from single-cell transcriptome sequencing, were published in 2017 and were the first omics data within the subclass Trichostomatia. Taxonomy A separate genus – ''Neobalantidium'' – has been created for several ...
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Merozoites
Apicomplexans, a group of intracellular parasites, have life cycle stages that allow them to survive the wide variety of environments they are exposed to during their complex life cycle. Each stage in the life cycle of an apicomplexan organism is typified by a ''cellular variety'' with a distinct morphology and biochemistry. Not all apicomplexa develop all the following cellular varieties and division methods. This presentation is intended as an outline of a hypothetical generalised apicomplexan organism. Methods of asexual replication Apicomplexans (sporozoans) replicate via ways of multiple fission (also known as schizogony). These ways include , and , although the latter is sometimes referred to as schizogony, despite its general meaning. Merogony is an asexually reproductive process of apicomplexa. After infecting a host cell, a trophozoite ( see glossary below) increases in size while repeatedly replicating its nucleus and other organelles. During this process, the ...
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Gametocyte
A gametocyte is a eukaryotic germ cell that divides by mitosis into other gametocytes or by meiosis into gametids during gametogenesis. Male gametocytes are called ''spermatocytes'', and female gametocytes are called ''oocytes''. Development The development of gametogonia to primary gametocytes is called gametocytogenesis. The further development of primary gametocytes to secondary gametocytes is a part of gametidogenesis. Gametogenesis is the formation or production of gametes (taking place during meiosis). The development and maturation of sex cells also takes place during meiosis. Gametogenesis is also the process of formation in male and female gametes that occur in the gonads (ovary and testis). Both male and female produce gametes. Male gametocytes are called spermatocytes and female gametocytes are called oocytes. The term gametocyte is also used, for example, when talking about gametocytes of species like ''Plasmodium falciparum'' or ''Plasmodium vivax'', which transmit ...
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Schizont
Apicomplexans, a group of intracellular parasites, have life cycle stages that allow them to survive the wide variety of environments they are exposed to during their complex life cycle. Each stage in the life cycle of an apicomplexan organism is typified by a ''cellular variety'' with a distinct morphology and biochemistry. Not all apicomplexa develop all the following cellular varieties and division methods. This presentation is intended as an outline of a hypothetical generalised apicomplexan organism. Methods of asexual replication Apicomplexans (sporozoans) replicate via ways of multiple fission (also known as schizogony). These ways include , and , although the latter is sometimes referred to as schizogony, despite its general meaning. Merogony is an asexually reproductive process of apicomplexa. After infecting a host cell, a trophozoite ( see glossary below) increases in size while repeatedly replicating its nucleus and other organelles. During this process, th ...
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Malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, Epileptic seizure, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected ''Anopheles'' mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial Immunity (medical), resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquitoes themselves are harmed by malaria, causing reduced lifespans in those infected by it. Malaria is caused by protozoa, single-celled microorganisms of the genus ''Plasmodium''. It is spread exclusively through bites of infected female ...
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Hepatocyte
A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: * Protein synthesis * Protein storage * Transformation of carbohydrates * Synthesis of cholesterol, bile salts and phospholipids * Detoxification, modification, and excretion of exogenous and endogenous substances * Initiation of formation and secretion of bile Structure The typical hepatocyte is cubical with sides of 20-30  μm, (in comparison, a human hair has a diameter of 17 to 180 μm).The diameter of human hair ranges from 17 to 181 μm. The typical volume of a hepatocyte is 3.4 x 10−9 cm3. Smooth endoplasmic reticulum is abundant in hepatocytes, in contrast to most other cell types. Microanatomy Hepatocytes display an eosinophilic cytoplasm, reflecting numerous mitochondria, and basophilic stippling due to large amounts of rough endoplasmic reticulum and free ribosomes. Brown lipofuscin granules are also observed (wit ...
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