Trinder Spot Test
The Trinder spot test is a diagnostic test used in medicine to determine exposure to salicylates, particularly to salicylic acid. The test employs the Trinder reagent (a.k.a. Trinder solution) which is mixed with a patient's urine. The colour change, resulting from the Trinder reaction, is immediate, enabling rapid bedside assessment. The Trinder solution/reagent is a pre-mixed solution of 10% ferric chloride. It can be prepared by combining 40 g of mercuric chloride and 40 g of ferric nitrate in 850 ml of type II deionized water, and then adding 10 ml of concentrated hydrochloric acid to the solution and diluting to a volume of 1 litre with more type II deionized water. The test for the Trinder reaction is to mix 1 ml of urine with 1 ml of the Trinder reagent in a test tube. The test is positive if a colour change results. The specific colour changes are: ;blue or purple:positive test ;no change:negative test ;brown:false-positive test caused by the presence of phenothiazin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Salicylate
Salicylic acid is an organic compound with the formula HOC6H4COOH. A colorless (or white), bitter-tasting solid, it is a precursor to and a metabolite of acetylsalicylic acid (aspirin). It is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen. The name is from Latin for willow tree, from which it was initially identified and derived. It is an ingredient in some anti-acne products. Salts and esters of salicylic acid are known as salicylates. Uses Medicine Salicylic acid as a medication is commonly used to remove the outermost layer of the skin. As such, it is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis. Similar to other hydroxy acids, salicylic acid is an ingredient in many skincare products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, acanthosis nigricans, ichthyosis, and warts. Uses ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Royal Infirmary
Royal Infirmary may refer to a number of hospitals in the United Kingdom: *England **Blackburn Royal Infirmary ** Bradford Royal Infirmary **Bolton Royal Infirmary **Bristol Royal Infirmary ** Chester Royal Infirmary **Derbyshire Royal Infirmary **Doncaster Royal Infirmary ** Gloucestershire Royal Infirmary ** Royal Halifax Infirmary **Huddersfield Royal Infirmary **Hull Royal Infirmary **Lancaster Royal Infirmary **Leicester Royal Infirmary **Liverpool Royal Infirmary ** Royal Infirmary for Children and Women, Lambeth, London **Manchester Royal Infirmary **Royal Victoria Infirmary, Newcastle ** North Staffordshire Royal Infirmary ** Preston Royal Infirmary ** Salford Royal Infirmary **Sheffield Royal Infirmary *Scotland **Aberdeen Royal Infirmary **Dumfries and Galloway Royal Infirmary **Dundee Royal Infirmary **Edinburgh Royal Infirmary ** Falkirk Royal Infirmary **Glasgow Royal Infirmary ** Greenock Royal Infirmary ** Montrose Royal Infirmary **Perth Royal Infirmary ** Stirling Ro ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bromazepam
Bromazepam, sold under many brand names, is a benzodiazepine. It is mainly an anxiolytic, anti-anxiety agent with similar side effects to diazepam. In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery. Bromazepam typically comes in doses of 1.5 mg, 3 mg and 6 mg tablets. It was patented in 1961 by Hoffmann-La Roche, Roche and approved for medical use in 1974. Medical uses Medical uses include treatment of severe anxiety. Despite certain side effects and the emergence of alternative products (e.g. pregabalin), benzodiazepine medication remains an effective way of reducing problematic symptoms, and is typically deemed effective by patients and medical professionals. Similarly to other intermediate-acting depressants, it may be used as hypnotic medication or in order to mitigate withdrawal effects of alcohol (drug), alcohol consumption. Pharmacology Bromazepam is a "classical" benzodiazepine; o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Norfloxacin
Norfloxacin, sold under the brand name Noroxin among others, is an antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ... that belongs to the class of fluoroquinolone antibiotics. It is used to treat urinary tract infections, gynecological infections, inflammation of the prostate gland, gonorrhea and bladder infection. Eye drops were approved for use in children older than one year of age. Norfloxacin is associated with a number of rare serious adverse reactions as well as spontaneous tendon ruptures and irreversible peripheral neuropathy. Tendon problems may manifest long after therapy had been completed and in severe cases may result in lifelong disabilities. It was patented in 1977 and approved for medical use in 1983. Medical uses The initial approval by the Food ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ciprofloxacin
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. For some infections it is used in addition to other antibiotics. It can be taken by mouth, as eye drops, as ear drops, or intravenously. Common side effects include nausea, vomiting, and diarrhea. Severe side effects include tendon rupture, hallucinations, and nerve damage. In people with myasthenia gravis, there is worsening muscle weakness. Rates of side effects appear to be higher than some groups of antibiotics such as cephalosporins but lower than others such as clindamycin. Studies in other animals raise concerns regarding use in pregnancy. No problems were identified, however, in the children of a small number of women who took the medication. It appear ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oxytetracycline
Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered. Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot grow, multiply and increase in numbers. Oxytetracycline therefore stops the spread of the infection, and the remaining bacteria are killed by the immune system or eventually die. Oxytetracycline is active against a wide variety of bacteria. However, some strains of bacteria have developed resistance to this antibiotic, which has reduced its effectiveness for treating some types of infections. Oxytetracycline is used to treat infections caused by ''Chlamydia'', such as psittacosis, trachoma, and urethritis, and infections caused by '' Mycoplasma'' organisms, such as pneumonia. Oxytetracycline is used to treat acne, due to its activity against the bacteria on the skin that influence the development of acne ('' Cutibacterium acnes''). It ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Methyl Salicylate
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula C8H8O3. It is the methyl ester of salicylic acid. It is a colorless, viscous liquid with a sweet, fruity odor reminiscent of root beer (in which it is used as a flavoring), but often association (psychology), associatively called "minty", as it is an ingredient in mint candies. It is produced by many species of plants, particularly wintergreens. It is also produced synthetically, used as a fragrance and as a flavoring agent. Biosynthesis and occurrence Methyl salicylate was first isolated (from the plant ''Gaultheria procumbens'') in 1843 by the French chemist Auguste André Thomas Cahours (1813–1891), who identified it as an ester of salicylic acid and methanol. The biosynthesis of methyl salicylate arises via the hydroxylation of benzoic acid by a cytochrome P450 followed by reaction with a methyltransferase enzyme. Methyl salicylate as a plant metabolite Many plants produce ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Salicylamide
Salicylamide (''o''-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009, and Excedrin used the ingredient from 1960 to 1980 in conjunction with aspirin, acetaminophen, and caffeine. It was used in later formulations of Vincent's powders in Australia as a substitute for phenacetin. Derivatives Derivatives of salicylamide include ethenzamide, labetalol, medroxalol, otilonium, oxyclozanide, salicylanilide, niclosamide, and raclopride. See also *4-Aminosalicylic acid *Mesalazine *Salsalate Salsalate is a medication that belongs to the salicylate and nonsteroidal anti-inflammatory drug (NSAID) classes. Salsalate is the generic name of a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Salicylic Acid
Salicylic acid is an organic compound with the formula HOC6H4COOH. A colorless (or white), bitter-tasting solid, it is a precursor to and a active metabolite, metabolite of acetylsalicylic acid (aspirin). It is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen. The name is from Latin for willow tree, from which it was initially identified and derived. It is an ingredient in some anti-acne products. Salts and esters of salicylic acid are known as salicylates. Uses Medicine Salicylic acid as a medication is commonly used to remove the outermost layer of the skin. As such, it is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis. Similar to other hydroxy acids, salicylic acid is an ingredient in many skincare products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, Corn (medicine), corns, keratosis pilaris, acanthosis nigricans, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Further Reading
Further or furthur, alternatively farther, may refer to: * ''Furthur'' (bus), the Merry Pranksters' psychedelic bus *Further (band), a 1990s American indie rock band *Furthur (band) Furthur was an American rock band founded in 2009 by former Grateful Dead members Bob Weir and Phil Lesh. The original lineup also included John Kadlecik of Dark Star Orchestra on lead guitar, RatDog's Jeff Chimenti on keyboards and Jay Lane on p ..., a band formed in 2009 by Bob Weir and Phil Lesh * ''Further'' (The Chemical Brothers album), 2010 * ''Further'' (Flying Saucer Attack album), 1995 * ''Further'' (Geneva album), 1997, and a song from the album * ''Further'' (Richard Hawley album), 2019 * ''Further'' (Solace album), 2000 * ''Further'' (Outasight album), 2009 * "Further" (VNV Nation song), a song by VNV Nation *"Further", a song by Longview from the album '' Mercury'', 2003 * Further Triennial, an announced contemporary art triennial focusing on Northern California artists, debuting in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sunderland, Tyne And Wear
Sunderland () is a port City status in the United Kingdom, city and metropolitan borough in Tyne and Wear, England. It is a port at the mouth of the River Wear on the North Sea, approximately south-east of Newcastle upon Tyne. It is the most populous settlement in the Wearside conurbation and the second most populous settlement in North East England after Newcastle. Sunderland was once known as 'the largest shipbuilding town in the world' and once made a quarter of all of the world's ships from its famous yards, which date back to 1346 on the River Wear. The centre of the modern city is an amalgamation of three settlements founded in the Anglo-Saxons, Anglo-Saxon era: Monkwearmouth, on the north bank of the Wear, and Sunderland and Bishopwearmouth on the south bank. Monkwearmouth contains St Peter's Church, Monkwearmouth, St Peter's Church, which was founded in 674 and formed part of Monkwearmouth–Jarrow Abbey, a significant centre of learning in the seventh and eighth cent ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hyperbilirubinemia
Bilirubin (BR) (adopted from German, originally bili—bile—plus ruber—red—from Latin) is a red-orange compound that occurs in the normcomponent of the straw-yellow color in urine. Another breakdown product, stercobilin, causes the brown color of feces. Although bilirubin is usually found in animals rather than plants, at least one plant species, ''Strelitzia nicolai'', is known to contain the pigment. Structure Bilirubin consists of an open-chain tetrapyrrole. It is formed by oxidative cleavage of a porphyrin in heme, which affords biliverdin. Biliverdin is reduced to bilirubin. After conjugation with glucuronic acid, bilirubin is water-soluble and can be excreted. Bilirubin is structurally similar to the pigment phycobilin used by certain algae to capture light energy, and to the pigment phytochrome used by plants to sense light. All of these contain an open chain of four pyrrolic rings. Like these other pigments, some of the double-bonds in bilirubin isomerize whe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |