Salicylamide (''o''-hydroxybenzamide or
amide of salicyl) is a non-prescription
drug
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...
with
analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
and
antipyretic properties. Its medicinal uses are similar to those of
aspirin.
Salicylamide is used in combination with both
aspirin and
caffeine in the
over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy
BC Powder
BC Powder is an American brand of over-the-counter analgesic pain reliever owned by Prestige Consumer Healthcare and manufactured in Washington, DC.
Ingredients
Originally produced at the Hepolscheiemer Clinic in Graz, Austria, it contains 84 ...
but was removed from the formulation in 2009, and
Excedrin used the ingredient from
1960 to 1980 in conjunction with
aspirin,
acetaminophen
Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol.
At a standard dose, paracetamol only slightly decreases body temperature; it is inferior ...
, and
caffeine. It was used in later formulations of
Vincent's powders
Vincent Chemical Company was an Australian business noted for manufacture of a popular compound analgesic "Vincent's APC"
History
Dr. Harry John Clayton (ca.1887 – 31 October 1928) of Macquarie Street and medical superintendent of the Royal Pr ...
in Australia as a substitute for
phenacetin
Phenacetin (acetophenetidin, ''N''-(4-ethoxyphenyl)acetamide) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887. It was withdrawn from medicinal use as dangerous from the 1970s (e.g., withdrawn ...
.
Derivatives
Derivatives
The derivative of a function is the rate of change of the function's output relative to its input value.
Derivative may also refer to:
In mathematics and economics
*Brzozowski derivative in the theory of formal languages
*Formal derivative, an ...
of salicylamide include
ethenzamide,
labetalol,
medroxalol
Medroxalol is a vasodilator beta blocker also classified as a mixed receptor blocker as it blocks both alpha and beta receptors.
Synthesis
For the first step, salicylamide (1) is the subject of a Friedel-Crafts acetylation and then the aromati ...
,
lopirin,
otilonium,
oxyclozanide,
salicylanilide,
niclosamide, and
raclopride.
See also
*
4-Aminosalicylic acid
*
Mesalazine
*
Salsalate
References
External links
Safety MSDS data
{{Prostanoidergics
Analgesics
Antipyretics
3-Hydroxypropenals