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Salicylamide (''o''-hydroxybenzamide or amide of salicyl) is a non-prescription
drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...
with
analgesic An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
and antipyretic properties. Its medicinal uses are similar to those of aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy
BC Powder BC Powder is an American brand of over-the-counter analgesic pain reliever owned by Prestige Consumer Healthcare and manufactured in Washington, DC. Ingredients Originally produced at the Hepolscheiemer Clinic in Graz, Austria, it contains 84 ...
but was removed from the formulation in 2009, and Excedrin used the ingredient from 1960 to 1980 in conjunction with aspirin,
acetaminophen Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior ...
, and caffeine. It was used in later formulations of
Vincent's powders Vincent Chemical Company was an Australian business noted for manufacture of a popular compound analgesic "Vincent's APC" History Dr. Harry John Clayton (ca.1887 – 31 October 1928) of Macquarie Street and medical superintendent of the Royal Pr ...
in Australia as a substitute for
phenacetin Phenacetin (acetophenetidin, ''N''-(4-ethoxyphenyl)acetamide) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887. It was withdrawn from medicinal use as dangerous from the 1970s (e.g., withdrawn ...
.


Derivatives

Derivatives The derivative of a function is the rate of change of the function's output relative to its input value. Derivative may also refer to: In mathematics and economics *Brzozowski derivative in the theory of formal languages *Formal derivative, an ...
of salicylamide include ethenzamide, labetalol,
medroxalol Medroxalol is a vasodilator beta blocker also classified as a mixed receptor blocker as it blocks both alpha and beta receptors. Synthesis For the first step, salicylamide (1) is the subject of a Friedel-Crafts acetylation and then the aromati ...
, lopirin, otilonium, oxyclozanide, salicylanilide, niclosamide, and raclopride.


See also

* 4-Aminosalicylic acid * Mesalazine * Salsalate


References


External links


Safety MSDS data
{{Prostanoidergics Analgesics Antipyretics 3-Hydroxypropenals