Transhydrogenase

	Transhydrogenase Transhydrogenase may stand for * NAD(P)+ transhydrogenase (Re/Si-specific) * NAD(P)+ transhydrogenase (Si-specific) * Proton-Translocating NAD(P)+ Transhydrogenase * Hydroxyacid-oxoacid transhydrogenase * Glutathione—cystine transhydrogenase * Lactate—malate transhydrogenase * Glutathione—homocystine transhydrogenase * Glutathione—CoA-glutathione transhydrogenase In enzymology, a glutathione—CoA-glutathione transhydrogenase () is an enzyme that catalyzes the chemical reaction :CoA + glutathione disulfide \rightleftharpoons CoA-glutathione + glutathione Thus, the two substrates of this enzyme are CoA ... {{enzyme index ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	NAD(P)+ Transhydrogenase (Re/Si-specific) In enzymology, a NAD(P)+ transhydrogenase (''Re''/''Si''-specific () is an enzyme that catalyzes the chemical reaction :NADPH + NAD+ \rightleftharpoons NADP+ + NADH Thus, the two substrates of this enzyme are NADPH and NAD+, whereas its two products are NADP+ and NADH. This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with NAD+ or NADP+ as acceptor. This enzyme participates in nicotinate and nicotinamide metabolism. Nomenclature The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is NADPH:NAD+ oxidoreductase (''Re''/''Si''-specific). Other names in common use include pyridine nucleotide transhydrogenase, transhydrogenase, NAD(P)+ transhydrogenase, nicotinamide adenine dinucleotide (ph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Proton-Translocating NAD(P)+ Transhydrogenase Proton-Translocating NAD(P)+ Transhydrogenase (E.C is an enzyme in that catalyzes the translocation of hydrons that are connected to the redox reaction NADH + NADP+ + H+outside => NAD+ + NADPH + H+inside EC Number 7.1.1.1 EC 7 – Translocases are a grouping of enzymes with a common function of assisting to move a molecule, typically across a membrane. EC 7.1 – enzymes that catalyze translocation of hydrons (the positive cations of all hydrogen isotopes e.g. protons, deuterons, tritons) EC 7.1.1 – enzymes that catalyze translocation of hydrons that have a tie to oxidoreductase reactions EC 7.1.1.1 – proton-translocating NAD(P)+ transhydrogenase. Reaction pathway The reaction that this enzyme catalyzes is NADH + NADP+ + H+outside => NAD+ + NADPH + H+inside This redox reaction is a transfer of hydride equivalents from NADH to NADP+ coupled to a translocation of protons across a membrane. NADP+ is reduced to NADPH by NADH, which is oxidized into NAD+. This reduction is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Glutathione—cystine Transhydrogenase In enzymology, a glutathione—cystine transhydrogenase () is an enzyme that catalyzes the chemical reaction :2 glutathione + cystine \rightleftharpoons glutathione disulfide + 2 cysteine Thus, the two substrates of this enzyme are glutathione and cystine, whereas its two products are glutathione disulfide and cysteine. This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is glutathione:cystine oxidoreductase. Other names in common use include GSH-cystine transhydrogenase, and NADPH-dependent GSH-cystine transhydrogenase. This enzyme participates in cysteine metabolism and glutathione metabolism Glutathione (GSH, ) is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by sources such as reactive oxygen species, free radicals, pe .... Referen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Lactate—malate Transhydrogenase In enzymology, a lactate—malate transhydrogenase () is an enzyme that catalyzes the chemical reaction :(S)-lactate + oxaloacetate \rightleftharpoons pyruvate + malate Thus, the two substrates of this enzyme are (S)-lactate and oxaloacetate, whereas its two products are pyruvate and malate. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (S)-lactate:oxaloacetate oxidoreductase. This enzyme is also called malate-lactate transhydrogenase. This enzyme participates in pyruvate metabolism. It employs one cofactor, nicotinamide D-ribonucleotide Niacinamide or Nicotinamide (NAM) is a form of vitamin B3 found in food and used as a dietary supplement and medication. As a supplement, it is used by mouth to prevent and treat pellagra (niacin deficiency). While nicotinic acid (niacin) may .... References Further reading * * EC 1.1.99 Enzy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Hydroxyacid-oxoacid Transhydrogenase In enzymology, a hydroxyacid-oxoacid transhydrogenase () is an enzyme that catalyzes the chemical reaction :(S)-3-hydroxybutanoate + 2-oxoglutarate \rightleftharpoons acetoacetate + (R)-2-hydroxyglutarate Thus, the two substrates of this enzyme are (S)-3-hydroxybutanoate and 2-oxoglutarate, whereas its two products are acetoacetate and (R)-2-hydroxyglutarate. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase. This enzyme is also called transhydrogenase, hydroxy acid-oxo acid. See also * D2HGDH * L2HGDH * 2-hydroxyglutarate synthase * 2-hydroxyglutarate dehydrogenase * Alpha-Hydroxyglutaric acid * 2-Hydroxyglutaric aciduria 2-hydroxyglutaric aciduria is a rare neurometabolic disorder characterized by the significantly elevated levels of hydroxyglutaric acid in one's urine. It is either autosoma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Glutathione—homocystine Transhydrogenase In enzymology, a glutathione—homocystine transhydrogenase () is an enzyme that catalyzes the chemical reaction :2 glutathione + homocystine \rightleftharpoons glutathione disulfide + 2 homocysteine Thus, the two substrates of this enzyme are glutathione and homocystine, whereas its two products are glutathione disulfide and homocysteine. This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is glutathione:homocystine oxidoreductase. This enzyme participates in methionine metabolism and glutathione metabolism Glutathione (GSH, ) is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by sources such as reactive oxygen species, free radicals, pe .... References * EC 1.8.4 Enzymes of unknown structure {{1.8-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]