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Tom Isaacs (fundraiser)
Tom Isaacs (2 April 1968 – 31 May 2017) was a British charity fundraiser and the President of The Cure Parkinson's Trust, which he co-founded. Among other achievements, he completed a 4,500-mile charity walk around the coast of Britain in order to raise funds for research into Parkinson's disease Isaacs, the son of a solicitor, trained as a surveyor, but was diagnosed with Parkinson's Disease in his mid-twenties, while working in London. He went on to found The Cure Parkinson's Trust, with others he had met in the course of his sponsored walk, and raised around £350,000 in total for medical research. He was named Charity Personality of the Year in 2004 and was one of the bearers of the Olympic torch in 2012. He was invited to meet Pope Francis after speaking at the Euro Stem Cell consortium in Rome. Isaacs was one of the participants in a revolutionary trial of the drug GDNF which took place between 2012 and 2017, in which 41 Parkinson's sufferers had surgery to introduce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common. The most obvious early symptoms are tremor, rigidity, slowness of movement, and difficulty with walking. Cognitive and behavioral problems may also occur with Depression (mood), depression, anxiety, and apathy occurring in many people with PD. Parkinson's disease dementia becomes common in the advanced stages of the disease. Those with Parkinson's can also have problems with their sleep and sensory systems. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain, leading to a dopamine deficit. The cause of this cell death is poorly understood, but involves the build-up of protein, misfolded proteins into Lewy bodies in the neurons. Collectively, the main motor sym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pope Francis
Pope Francis ( la, Franciscus; it, Francesco; es, link=, Francisco; born Jorge Mario Bergoglio, 17 December 1936) is the head of the Catholic Church. He has been the bishop of Rome and sovereign of the Vatican City State since 13 March 2013. Francis is the first pope to be a member of the Society of Jesus, the first from the Americas, the first from the Southern Hemisphere, and the first pope from outside Europe since Pope Gregory III, Gregory III, a Syrian who reigned in the 8th century. Born in Buenos Aires, Argentina, Bergoglio worked for a time as a Bouncer (doorman), bouncer and a janitor as a young man before training to be a chemist and working as a technician in a food science laboratory. After recovering from a severe illness, he was inspired to join the Jesuits, Society of Jesus (Jesuits) in 1958. He was ordained a Catholic priest in 1969, and from 1973 to 1979 was the Jesuit provincial superior in Argentina. He became the archbishop of Buenos Aires in 1998 and was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GDNF
Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the ''GDNF'' gene. GDNF is a small protein that potently promotes the survival of many types of neurons. It signals through GFRα receptors, particularly GFRα1. It is also responsible for the determination of spermatogonia into primary spermatocytes, i.e. it is received by RET proto-oncogene (RET) and by forming gradient with SCF it divides the spermatogonia into two cells. As the result there is retention of spermatogonia and formation of spermatocyte. GDNF family of ligands (GFL) GDNF was discovered in 1991, and is the first member of the GDNF family of ligands (GFL) found. Function GDNF is highly distributed throughout both the peripheral and central nervous system. It can be secreted by astrocytes, oligodendrocytes, Schwann cells, motor neurons, and skeletal muscle during the development and growth of neurons and other peripheral cells. The GDNF gene encodes a highly conserv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgery
Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function, appearance, or to repair unwanted ruptured areas. The act of performing surgery may be called a surgical procedure, operation, or simply "surgery". In this context, the verb "operate" means to perform surgery. The adjective surgical means pertaining to surgery; e.g. surgical instruments or surgical nurse. The person or subject on which the surgery is performed can be a person or an animal. A surgeon is a person who practices surgery and a surgeon's assistant is a person who practices surgical assistance. A surgical team is made up of the surgeon, the surgeon's assistant, an anaesthetist, a circulating nurse and a surgical technologist. Surgery usually span ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Michael J
''The'' () is a grammatical article in English, denoting persons or things that are already or about to be mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the most frequently used word in the English language; studies and analyses of texts have found it to account for seven percent of all printed English-language words. It is derived from gendered articles in Old English which combined in Middle English and now has a single form used with nouns of any gender. The word can be used with both singular and plural nouns, and with a noun that starts with any letter. This is different from many other languages, which have different forms of the definite article for different genders or numbers. Pronunciation In most dialects, "the" is pronounced as (with the voiced dental fricative followed by a schwa) when followed by a consonant sound, and as (homophone of the archaic p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1968 Births
The year was highlighted by Protests of 1968, protests and other unrests that occurred worldwide. Events January–February * January 5 – "Prague Spring": Alexander Dubček is chosen as leader of the Communist Party of Czechoslovakia. * January 10 – John Gorton is sworn in as 19th Prime Minister of Australia, taking over from John McEwen after being 1968 Liberal Party of Australia leadership election, elected leader of the Liberal Party of Australia, Liberal Party the previous day, following the disappearance of Harold Holt. Gorton becomes the only Australian Senate, Senator to become Prime Minister, though he immediately transfers to the Australian House of Representatives, House of Representatives through the 1968 Higgins by-election in Holt's vacant seat. * January 15 – The 1968 Belice earthquake in Sicily kills 380 and injures around 1,000. * January 21 ** Vietnam War: Battle of Khe Sanh – One of the most publicized and controversial battles of the war ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2017 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Charity And Campaign Group Workers
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * Bri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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