Thymolphthalexone
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Thymolphthalexone
Thymolphthalexone is a chemical compound from the group of iminodiacetic acid derivatives of thymolphthalein. Its chemical formula is . This is a metallochromic indicator widely used in complexometric titrations, particularly for the determination of transition metals. The compound features a thymolphthalein-derived core linked to aminopolycarboxylic acid functional groups. This hybrid architecture grants the compound the ability to preferentially bind specific metal ions through coordinated interactions. Synthesis Thymolphthalexone can be obtained by Mannich condensation of formaldehyde and iminodiacetic acid with thymolphthalein. Physical properties Thymolphthalexone forms a white crystalline powder soluble in water and organic solvents. Uses Thymolphthalexone and its sodium salt are used as an indicator or photometric reagent for alkaline metal ions, such as those of calcium, strontium, barium, and others.{{cite journal , last1=Babaei , first1=Ali , last2=Babazadeh , first2 ...
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Phenolphthalein
Phenolphthalein ( ) is a chemical compound with the chemical formula, formula carbon, C20hydrogen, H14oxygen, O4 and is often written as "HIn", "HPh", "phph" or simply "Ph" in shorthand notation. Phenolphthalein is often used as an indicator in acid–base titrations. For this application, it turns colorless in acidic solutions and pink in base (chemistry), basic solutions. It belongs to the class of dyes known as phthalein dyes. Phenolphthalein is slightly soluble in water and usually is dissolved in Alcohol (chemistry), alcohols in experiments. It is a weak acid, which can lose Hydrogen ion, H+ ions in solution. The nonionized phenolphthalein molecule is colorless and the double deprotonated phenolphthalein ion is Fuchsia (color), fuchsia. Further proton loss in higher pH occurs slowly and leads to a colorless form. Phenolphthalein ion in concentrated sulfuric acid is orange red due to sulfonation. Uses pH indicator Phenolphthalein's common use is as an indicator in acid-ba ...
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Thymolphthalein
Thymolphthalein is a phthalein dye used as an acid– base ( pH) indicator. Its transition range is around pH 9.3–10.5. Below this pH, it is colorless; above, it is blue. The molar extinction coefficient In chemistry, the molar absorption coefficient or molar attenuation coefficient () is a measurement of how strongly a chemical species absorbs, and thereby attenuates, light at a given wavelength. It is an intrinsic property of the species. The ... for the blue thymolphthalein dianion is 38,000 M−1 cm−1 at 595 nm. Thymolphthalein is also known to have use as a laxative and for disappearing ink. Preparation Thymolphthalein can be synthesized from thymol and phthalic anhydride. : See also * Phenolphthalein * Thymolphthalexone References PH indicators Triarylmethane dyes Phthalides Phenols Isopropyl compounds {{Ether-stub ...
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Iminodiacetic Acid
Iminodiacetic acid is the organic compound with the formula HN(CH2CO2H)2, often abbreviated to IDA. A white solid, the compound is a dicarboxylic acid amine (the nitrogen atom forms a secondary amino group, not an imino group as the name suggests). IDA is a popular chelating ligand, first introduced in the early 1950s by Schwarzenbach. Ligand The iminodiacetate dianion is typically a tridentate ligand, forming metal complexes by forming two, fused, five membered chelate rings. IDA thus forms stronger complexes than the bidentate ligand glycine and weaker complexes than the tetradentate ligand nitrilotriacetic acid. IDA can also act as a bidentate ligand through its two carboxylate groups. Several technetium-99''m'' complexes with bidentate IDA derivatives are used in cholescintigraphy scans (the so-called "hepatobiliary iminodiacetic acid scans") to evaluate the health and function of the gallbladder. Common IDA derivatives include lidofenin, mebrofenin, and disofenin tha ...
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Springer Science & Business Media
Springer Science+Business Media, commonly known as Springer, is a German multinational publishing company of books, e-books and peer-reviewed journals in science, humanities, technical and medical (STM) publishing. Originally founded in 1842 in Berlin, it expanded internationally in the 1960s, and through mergers in the 1990s and a sale to venture capitalists it fused with Wolters Kluwer and eventually became part of Springer Nature in 2015. Springer has major offices in Berlin, Heidelberg, Dordrecht, and New York City. History Julius Springer founded Springer-Verlag in Berlin in 1842 and his son Ferdinand Springer grew it from a small firm of 4 employees into Germany's then second-largest academic publisher with 65 staff in 1872.Chronology
". Springer Science+Business Media.
In 1964, Springer expanded its business internationally, ...
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