Therapure BioPharma Inc
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Therapure BioPharma Inc
Therapure BioPharma, Inc. is a Canadian biopharmaceutical industry and biotechnology company, headquartered in Mississauga, Ontario, a privately held, integrated Contract Development and Manufacturing Organization (CDMO). Founded in 2008, the firm provides a range of therapeutic protein development and manufacturing services including; technology transfer & process development, analytical development and testing, scale up and cGMP manufacturing, and aseptic fill/finish and lyophilization. , the company has over 90 employees. In 2020, Therapure was acquired by Resilience. Facility The 130,000 ft2 cGMP biopharmaceutical facility is a first of its kind in Canada as an article in BioBusiness indicated that Therapure has the capability to develop, manufacture, purify, and package protein therapeutics at very large and small scale. The facility was toured by Mississauga Mayor Hazel McCallion during the official launch. The great nephew of Dr. Frederick Banting Sir Frederick Grant B ...
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Biotechnology
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and con ...
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Mississauga, Ontario
Mississauga is a Canadian city in the province of Ontario. Situated on the north-western shore of Lake Ontario in the Regional Municipality of Peel, it borders Toronto (Etobicoke) to the east, Brampton to the north, Milton to the northwest, and Oakville to the southwest. With a population of 717,961 as of 2021, Mississauga is the seventh-most populous municipality in Canada, third-most in Ontario, and second-most in the Greater Toronto Area (GTA) after Toronto itself. However, for the first time in its history, the city's population declined according to the 2021 census, from a 2016 population of 721,599 to 717,961, a 0.5 per cent decrease. The growth of Mississauga was initially attributed to its proximity to Toronto. However, during the latter half of the 20th century, the city attracted a diverse and multicultural population. Over time, it built up a thriving, transit-oriented central business district of its own, which is now known as Mississauga City Centre. Malt ...
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Biotechnology
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and con ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ...
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Lyophilization
Freeze drying, also known as lyophilization or cryodesiccation, is a low temperature dehydration process that involves freezing the product and lowering pressure, thereby removing the ice by sublimation. This is in contrast to dehydration by most conventional methods that evaporate water using heat. Because of the low temperature used in processing, the rehydrated product retains many of its original qualities. When solid objects like strawberries are freeze dried the original shape of the product is maintained. If the product to be dried is a liquid, as often seen in pharmaceutical applications, the properties of the final product are optimized by the combination of excipients (i.e., inactive ingredients). Primary applications of freeze drying include biological (e.g., bacteria and yeasts), biomedical (e.g., surgical transplants), food processing (e.g., coffee), and preservation. History The Inca were freeze drying potatoes into chuño since the 13th century. The process in ...
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Biopharmaceutical
A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, they include vaccines, whole blood, blood components, allergenics, somatic cells, gene therapies, tissues, recombinant therapeutic protein, and living medicines used in cell therapy. Biopharmaceuticals can be composed of sugars, proteins, nucleic acids, or complex combinations of these substances, or may be living cells or tissues. They (or their precursors or components) are isolated from living sources—human, animal, plant, fungal, or microbial. They can be used in both human and animal medicine. Terminology surrounding biopharmaceuticals varies between groups and entities, with different terms referring to different subsets of therapeutics within the general biopharmaceutical category. The term biologics is often used more res ...
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Hazel McCallion
Hazel Mary Muriel McCallion (; February 14, 1921 – January 29, 2023) was a Canadian politician who served as the fifth mayor of Mississauga. First elected in November 1978, McCallion was mayor for 36 years until her retirement in 2014, making her the longest-serving mayor in the city's history. She was a successful candidate in twelve municipal elections, having been acclamation#Uncontested election, acclaimed twice and re-elected ten times. She was nicknamed "Hurricane Hazel" for her outspoken political style with reference to the Hurricane Hazel, hurricane of 1954, which had a considerable impact. When the 1979 Mississauga train derailment occurred early in her tenure, she helped oversee evacuation of 200,000 residents from the resulting explosion, fire, and spill of hazardous chemicals. Before marriage, McCallion played professional women's ice hockey while attending school in Montreal, then worked for engineering firm M.W. Kellogg Co., Canadian Kellogg, and was transferre ...
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Frederick Banting
Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian pharmacologist, orthopedist, and field surgeon. For his co-discovery of insulin and its therapeutic potential, Banting was awarded the Nobel Prize in Physiology or Medicine with John Macleod (physiologist), John Macleod. Banting and his student, Charles Best (medical scientist), Charles Best, isolated insulin at the University of Toronto in the lab of Scottish physiologist John Macleod. When he and Macleod received the 1923 Nobel Prize in Physiology or Medicine, Banting shared the honours and award money with Best. That same year, the government of Canada granted Banting a lifetime annuity to continue his work. Frederick Banting, who received the Nobel Prize at age 32, is the youngest Nobel laureate for Physiology/Medicine. Early life Banting was born on November 14, 1891, in his family's farmhouse in Essa, Ontario, two miles from nearby Alliston. He was the youngest of five children of ...
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Biotechnology Companies Of Canada
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and consequently, create ne ...
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Manufacturing Companies Based In Mississauga
Manufacturing is the creation or production of goods with the help of equipment, labor, machines, tools, and chemical or biological processing or formulation. It is the essence of the secondary sector of the economy. The term may refer to a range of human activity, from handicraft to high-tech, but it is most commonly applied to industrial design, in which raw materials from the primary sector are transformed into finished goods on a large scale. Such goods may be sold to other manufacturers for the production of other more complex products (such as aircraft, household appliances, furniture, sports equipment or automobiles), or distributed via the tertiary industry to end users and consumers (usually through wholesalers, who in turn sell to retailers, who then sell them to individual customers). Manufacturing engineering is the field of engineering that designs and optimizes the manufacturing process, or the steps through which raw materials are transformed into a final produc ...
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