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Therapeutic Targets Database
Therapeutic Target Database (TTD) is a pharmaceutical and medical repository constructed by the Innovative Drug Research and Bioinformatics Group (IDRB) at Zhejiang University, China and the Bioinformatics and Drug Design Group at the National University of Singapore. It provides information about known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. Detail knowledge about target function, sequence, 3D structure, ligand binding properties, enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ... nomenclature and drug structure, therapeutic class, and clinical development status. TTD is freely accessible without any login requirement. Statistics This database cu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ttd Logo
TTD may refer to: Places and organizations * Tirumala Tirupati Devasthanams, an independent trust which manages the Sri Venkateswara Temple in Andhra Pradesh, India * Portland-Troutdale Airport, IATA airport code * The Trade Desk, NASDAQ symbol Entertainment * ''Tic-Tac-Dough'', a game show * ''Transport Tycoon Deluxe'', a computer game Medicine * Therapeutic Targets Database, a database to provide information about the known and explored therapeutic targets * Trichothiodystrophy, a characteristic of Tay syndrome Other * Trinidad and Tobago dollar, ISO 4217 currency code * Terence Trent D'Arby, former stage name of singer Sananda Maitreya * Tombstone Tenzan Driver, the name of the finisher of Japanese pro wrestler, Hiroyoshi Tenzan * True time delay, an electrical property of a transmitting apparatus * Top Thrill Dragster Top Thrill Dragster is a hydraulically-launched steel roller coaster located at Cedar Point in Sandusky, Ohio, United States. Manufactured by Intamin a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zhejiang University
Zhejiang University, abbreviated as ZJU or Zheda and formerly romanized as Chekiang University, is a national public research university based in Hangzhou, Zhejiang, China. It is a member of the prestigious C9 League and is selected into the national higher education plans including Double First Class University Plan, Project 985, and Project 211; ZJU is consistently ranked among the top 5 academic institutions in mainland China. Founded as Qiushi Academy in 1897, it is the oldest university in Zhejiang and one of the oldest in China. After the 1911 Revolution, the university was shut down by the government in 1914 and was re-established as National Third Chungshan University in 1927 and renamed as National Chekiang University (NCKU) in 1928. During the presidency of Chu Kochen from 1936 to 1949, despite relocation due to World War II, the university became one of the famous four universities in China. British biochemist Joseph Needham hailed the university as "Cambri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National University Of Singapore
The National University of Singapore (NUS) is a national public research university in Singapore. Founded in 1905 as the Straits Settlements and Federated Malay States Government Medical School, NUS is the oldest autonomous university in the country. It offers degree programmes in a wide range of disciplines at both the undergraduate and postgraduate levels, including in the sciences, medicine and dentistry, design and environment, law, arts and social sciences, engineering, business, computing, and music. NUS is one of the most highly-ranked academic institutions in the world. It has consistently featured in the top 30 of the Quacquarelli Symonds (QS) World University Rankings and the Times Higher Education (THE) World University Rankings, and in the top 100 of the Academic Ranking of World Universities (ARWU). As of 2022-2023, NUS is 11th worldwide according to QS and 19th worldwide according to THE. NUS's main campus is located in the southwestern part of Singapore, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid resid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleic Acid
Nucleic acids are biopolymers, macromolecules, essential to all known forms of life. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. The two main classes of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). If the sugar is ribose, the polymer is RNA; if the sugar is the ribose derivative deoxyribose, the polymer is DNA. Nucleic acids are naturally occurring chemical compounds that serve as the primary information-carrying molecules in cells and make up the genetic material. Nucleic acids are found in abundance in all living things, where they create, encode, and then store information of every living cell of every life-form on Earth. In turn, they function to transmit and express that information inside and outside the cell nucleus to the interior operations of the cell and ultimately to the next generation of each living organism. The encoded informatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are Ribozyme, catalytic RNA molecules, called ribozymes. Enzymes' Chemical specificity, specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteins
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residues in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology Literature
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Databases
A chemical database is a database specifically designed to store chemical information. This information is about chemical and crystal structures, spectra, reactions and syntheses, and thermophysical data. Types of chemical databases Bioactivity database Bioactivity databases correlate structures or other chemical information to bioactivity results taken from bioassays in literature, patents, and screening programs. Chemical structures Chemical structures are traditionally represented using lines indicating chemical bonds between atoms and drawn on paper (2D structural formulae). While these are ideal visual representations for the chemist, they are unsuitable for computational use and especially for search and storage. Small molecules (also called ligands in drug design applications), are usually represented using lists of atoms and their connections. Large molecules such as proteins are however more compactly represented using the sequences of their amino acid bui ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Databases
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drugs In Singapore
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorption via a patch on the skin, suppository, or dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders. Pharmaceutical drugs are often classified into drug classes—groups of rel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Target (Biologie)
Target may refer to: Physical items * Shooting target, used in marksmanship training and various shooting sports ** Bullseye (target), the goal one for which one aims in many of these sports ** Aiming point, in field artillery, fixed at a specific target * Color chart (or reference card), the reference target used in digital imaging for accurate color reproduction Places * Target, Allier, France * Target Lake, a lake in Minnesota Terms * Target market, marketing strategy ** Target audience, intended audience or readership of a publication, advertisement, or type of message * In mathematics, the target of a function is also called the codomain * Target (cricket), the total number of runs a team needs to win People * Target (rapper), stage name of Croatian hip-hop artist Nenad Šimun * DJ Target, stage name of English grime DJ Darren Joseph, member of Roll Deep * Gui-Jean-Baptiste Target (1733–1807), French lawyer Art and media * The Target, a comic book c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
