Therac-25
The Therac-25 is a computer-controlled radiation therapy machine produced by Atomic Energy of Canada Limited (AECL) in 1982 after the Therac-6 and Therac-20 units (the earlier units had been produced in partnership with of France). The Therac-25 was involved in at least six accidents between 1985 and 1987, in which some patients were given massive overdoses of radiation. Because of concurrent programming errors (also known as race conditions), it sometimes gave its patients radiation doses that were hundreds of times greater than normal, resulting in death or serious injury. These accidents highlighted the dangers of software control of safety-critical systems. The Therac-25 has become a standard case study in health informatics, software engineering, and computer ethics. It highlights the dangers of engineer overconfidence after the engineers dismissed user-end reports, leading to severe consequences. History The French company CGR, a subsidiary of Thomson-CSF, man ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Atomic Energy Of Canada Limited
Atomic Energy of Canada Limited (AECL, Énergie atomique du Canada limitée, EACL) is a Canadian Crown corporation and the largest nuclear science and technology laboratory in Canada. AECL developed the CANDU reactor technology starting in the 1950s, and in October 2011 licensed this technology to Candu Energy. AECL describes its goal as ensuring that "Canadians and the world receive energy, environmental and economic benefits from nuclear science and technology – with confidence that nuclear safety and security are assured". Until October 2011, AECL was also the vendor of CANDU technology, which it had exported worldwide. Throughout the 1960s–2000s AECL marketed and built CANDU facilities in India, South Korea, Argentina, Romania, and the People's Republic of China. It is a member of the World Nuclear Association trade group. In addition, AECL manufactures nuclear medicine radioisotopes for supply to Nordion in Ottawa, Ontario, and is the world's largest supplier of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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PDP-11
The PDP–11 is a series of 16-bit minicomputers originally sold by Digital Equipment Corporation (DEC) from 1970 into the late 1990s, one of a set of products in the Programmed Data Processor (PDP) series. In total, around 600,000 PDP-11s of all models were sold, making it one of DEC's most successful product lines. The PDP-11 is considered by some experts to be the most popular minicomputer. The PDP–11 included a number of innovative features in its instruction set and additional general-purpose registers that made it easier to program than earlier models in the PDP series. Further, the innovative Unibus system allowed external devices to be more easily interfaced to the system using direct memory access, opening the system to a wide variety of peripherals. The PDP–11 replaced the PDP–8 in many real-time computing applications, although both product lines lived in parallel for more than 10 years. The ease of programming of the PDP–11 made it popular for general-pur ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Radiation Poisoning
Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. Symptoms can start within an hour of exposure, and can last for several months. Early symptoms are usually nausea, vomiting and loss of appetite. In the following hours or weeks, initial symptoms may appear to improve, before the development of additional symptoms, after which either recovery or death follows. ARS involves a total dose of greater than 0.7 Gy (70 rad), that generally occurs from a source outside the body, delivered within a few minutes. Sources of such radiation can occur accidentally or intentionally. They may involve nuclear reactors, cyclotrons, certain devices used in cancer therapy, nuclear weapons, or radiological weapons. It is generally divided into three types: bone marrow, gastrointestinal, and neurovascular syndrome, with bone m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Race Condition
A race condition or race hazard is the condition of an electronics, software, or other system where the system's substantive behavior is dependent on the sequence or timing of other uncontrollable events, leading to unexpected or inconsistent results. It becomes a bug when one or more of the possible behaviors is undesirable. The term ''race condition'' was already in use by 1954, for example in David A. Huffman's doctoral thesis "The synthesis of sequential switching circuits". Race conditions can occur especially in logic circuits or multithreaded or distributed software programs. Using mutual exclusion can prevent race conditions in distributed software systems. In electronics A typical example of a race condition may occur when a logic gate combines signals that have traveled along different paths from the same source. The inputs to the gate can change at slightly different times in response to a change in the source signal. The output may, for a brief period, chan ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Radiation Therapy
Radiation therapy or radiotherapy (RT, RTx, or XRT) is a therapy, treatment using ionizing radiation, generally provided as part of treatment of cancer, cancer therapy to either kill or control the growth of malignancy, malignant cell (biology), cells. It is normally delivered by a linear particle accelerator. Radiation therapy may be cure, curative in a number of types of cancer if they are localized to one area of the body, and have not metastasis, spread to other parts. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the canc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Safety-critical System
A safety-critical system or life-critical system is a system whose failure or malfunction may result in one (or more) of the following outcomes: * death or serious injury to people * loss or severe damage to equipment/property * environmental harm A safety-related system (or sometimes safety-involved system) comprises everything (hardware, software, and human aspects) needed to perform one or more safety functions, in which failure would cause a significant increase in the safety risk for the people or environment involved. Safety-related systems are those that do not have full responsibility for controlling hazards such as loss of life, severe injury or severe environmental damage. The malfunction of a safety-involved system would only be that hazardous in conjunction with the failure of other systems or human error. Some safety organizations provide guidance on safety-related systems, for example the Health and Safety Executive in the United Kingdom. Risks of this sort are ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Radiation Burn
A radiation burn is a damage to the skin or other biological tissue and organs as an effect of radiation. The radiation types of greatest concern are thermal radiation, radio frequency energy, ultraviolet light and ionizing radiation. The most common type of radiation burn is a sunburn caused by UV radiation. High exposure to X-rays during diagnostic medical imaging or radiotherapy can also result in radiation burns. As the ionizing radiation interacts with cells within the body—damaging them—the body responds to this damage, typically resulting in erythema—that is, redness around the damaged area. Radiation burns are often discussed in the same context as radiation-induced cancer due to the ability of ionizing radiation to interact with and damage DNA, occasionally inducing a cell to become cancerous. Cavity magnetrons can be improperly used to create surface and internal burning. Depending on the photon energy, gamma radiation can cause deep gamma burns, with 60Co int ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Beta Radiation
A beta particle, also called beta ray or beta radiation (symbol β), is a high-energy, high-speed electron or positron emitted by the radioactive decay of an atomic nucleus, known as beta decay. There are two forms of beta decay, β− decay and β+ decay, which produce electrons and positrons, respectively. Beta particles with an energy of 0.5 MeV have a range of about one metre in the air; the distance is dependent on the particle's energy and the air's density and composition. Beta particles are a type of ionizing radiation, and for radiation protection purposes, they are regarded as being more ionising than gamma rays, but less ionising than alpha particles. The higher the ionising effect, the greater the damage to living tissue, but also the lower the penetrating power of the radiation through matter. Beta decay modes β− decay (electron emission) An unstable atomic nucleus with an excess of neutrons may undergo β− decay, where a neutron is converted into a prot ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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X-ray
An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ranging from 10 Nanometre, nanometers to 10 Picometre, picometers, corresponding to frequency, frequencies in the range of 30 Hertz, petahertz to 30 Hertz, exahertz ( to ) and photon energies in the range of 100 electronvolt, eV to 100 keV, respectively. X-rays were discovered in 1895 in science, 1895 by the German scientist Wilhelm Röntgen, Wilhelm Conrad Röntgen, who named it ''X-radiation'' to signify an unknown type of radiation.Novelline, Robert (1997). ''Squire's Fundamentals of Radiology''. Harvard University Press. 5th edition. . X-rays can penetrate many solid substances such as construction materials and living tissue, so X-ray radiography is widely used in medical diagnostics (e.g., checking for Bo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Interlock (engineering)
An interlock is a feature that makes the state of two mechanisms or functions mutually dependent. It may consist of any electrical or mechanical devices, or systems. In most applications, an interlock is used to help prevent any damage to the machine or to the operator handling the machine. For example, elevators are equipped with an interlock that prevents the moving elevator from opening its doors and prevents the stationary elevator (with open doors) from moving. Interlocks may include sophisticated elements such as curtains of Infrared beam, infrared beams, photodetectors, simple Switch, switches, and lock and key, locks. It can also be a computer containing an interlocking computer program with digital electronics, digital or analogue electronics, analogue electronics. Trapped-key interlocking Trapped-key interlocking is a method of ensuring safety in industrial environments by forcing the operator through a predetermined sequence using a defined selection of keys, locks and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |