Theo Colborn
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Theo Colborn
Theodora Emily Colborn (née Decker; March 28, 1927 – December 14, 2014) was Founder and President Emerita of The Endocrine Disruption Exchange (TEDX), based in Paonia, Colorado, and Professor Emerita of Zoology at the University of Florida, Gainesville. She was an environmental health analyst, and best known for her studies on the health effects of endocrine disrupting chemicals. She died in 2014. Academic career In 1947, Colborn obtained a B.S. in Pharmacy from the College of Pharmacy at Rutgers University and became a pharmacist. In 1981, she graduated from Western State College of Colorado, Gunnison, with an M.A. in Science in freshwater ecology. In 1985, Colborn received a Fellowship from the Office of Technology Assessment, U.S. Congress. From there, in 1987, she joined the Conservation Foundation to provide scientific guidance for the 1990 book, ''Great Lakes, Great Legacy?'' in collaboration with the Institute for Research and Public Policy, Ottawa, Canada. In 198 ...
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Plainfield, New Jersey
Plainfield is a City (New Jersey), city in Union County, New Jersey, Union County, in the U.S. state of New Jersey. Nicknamed "The Queen City",About
City of Plainfield. Accessed December 29, 2021. "Plainfield Is Nicknamed 'The Queen City.'"
it serves as both a regional hub for Central Jersey, Central New Jersey and a bedroom suburb of the New York Metropolitan area, located in the Raritan River, Raritan Valley region. As of the 2020 United States census, the city's population, majority Latino (demonym), Latino for the first time, was 54,586. This was an increase of 4,778 (+9.6%) from the 2010 United States census, 2010 census count of 49,808, which in turn reflected an increase of 1,979 (+4.1%) from the 47,829 counted in the 2000 United States ...
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Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during chemical reaction, reactions with other chemical substance, substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both Basic research, basic and Applied science, applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth (botany), the formation of igneous rocks (geology), how atmospheric ozone is formed and how environmental pollutants are degraded (ecology), the prop ...
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Endocrine Disruption
Endocrine disruptors, sometimes also referred to as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds are chemicals that can interfere with endocrine (or hormonal) systems. These disruptions can cause numerous adverse human health outcomes, including alterations in sperm quality and fertility; abnormalities in sex organs‚ endometriosis‚ early puberty‚ altered nervous system or immune function; certain cancers; respiratory problems; metabolic issues; diabetes, obesity, or cardiovascular problems; growth, neurological and learning disabilities, and more. Found in many household and industrial products, endocrine disruptors "interfere with the synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body that are responsible for development, behavior, fertility, and maintenance of homeostasis (normal cell metabolism)." Any system in the body controlled by hormones can be derailed by hormone disrupto ...
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Transgenerational Epigenetics
Transgenerational epigenetic inheritance is the proposed transmission of epigenetic markers and modifications from one generation to multiple subsequent generations without altering the primary structure of DNA. Thus, the regulation of genes via epigenetic mechanisms can be heritable; the amount of transcripts and proteins produced can be altered by inherited epigenetic changes. In order for epigenetic marks to be heritable, however, they must occur in the gametes in animals, but since plants lack a definitive germline and can propagate, epigenetic marks in any tissue can be heritable. The inheritance of epigenetic marks in the immediate generation is referred to as intergenerational inheritance. In male mice, the epigenetic signal is maintained through the F1 generation. In female mice, the epigenetic signal is maintained through the F2 generation as a result of the exposure of the germline in the womb. Many epigenetic signals are lost beyond the F2/F3 generation and are no longer ...
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Persistent Organic Pollutants
Persistent organic pollutants (POPs) are organic compounds that are resistant to degradation through chemical, biological, and photolytic processes. They are toxic and adversely affect human health and the environment around the world. Because they can be transported by wind and water, most POPs generated in one country can and do affect people and wildlife far from where they are used and released. The effect of POPs on human and environmental health was discussed, with intention to eliminate or severely restrict their production, by the international community at the Stockholm Convention on Persistent Organic Pollutants in 2001. Most POPs are pesticides or insecticides, and some are also solvents, pharmaceuticals, and industrial chemicals. Although some POPs arise naturally (e.g. from volcanoes), most are man-made. The "dirty dozen" POPs identified by the Stockholm Convention include aldrin, chlordane, dieldrin, endrin, heptachlor, HCB, mirex, toxaphene, PCBs ...
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Apex Predator
An apex predator, also known as a top predator or superpredator, is a predator at the top of a food chain, without natural predators of its own. Apex predators are usually defined in terms of trophic dynamics, meaning that they occupy the highest trophic levels. Food chains are often far shorter on land, usually limited to being secondary consumers – for example, Gray wolf, wolves prey mostly upon large herbivores (primary consumers), which eat plants (primary producers). The apex predator concept is applied in wildlife management, conservation biology, conservation, and ecotourism. Apex predators have a long evolutionary history, dating at least to the Cambrian period when animals such as ''Anomalocaris'' and ''Timorebestia'' dominated the seas. Humans have for many centuries interacted with other apex predators including the wolf, Bird of prey, birds of prey, and cormorants to hunt game animals, birds, and fish respectively. More recently, humans have started interacting ...
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Great Lakes
The Great Lakes, also called the Great Lakes of North America, are a series of large interconnected freshwater lakes spanning the Canada–United States border. The five lakes are Lake Superior, Superior, Lake Michigan, Michigan, Lake Huron, Huron, Lake Erie, Erie, and Lake Ontario, Ontario (though hydrologically, Lake Michigan–Huron, Michigan and Huron are a single body of water, joined at the Straits of Mackinac). The Great Lakes Waterway enables modern travel and shipping by water among the lakes. The lakes connect to the Atlantic Ocean via the Saint Lawrence River, and to the Mississippi River basin through the Illinois Waterway. The Great Lakes are the largest group of freshwater lakes on Earth by total area and the second-largest by total volume. They contain 21% of the world's surface fresh water by volume. The total surface is , and the total volume (measured at the low water datum) is , slightly less than the volume of Lake Baikal (, 22–23% of the world's surface f ...
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Continuing Medical Education
Continuing medical education (CME) is continuing education (CE) that helps those in the medical field maintain competence and learn about new and developing areas of their field. These activities may take place as live events, written publications, online programs, audio, video, or other electronic media. Content for these programs is developed, reviewed, and delivered by faculty who are experts in their individual areas. Similar to the process used in academic journals, any potentially conflicting financial relationships for faculty members must be both disclosed and resolved in a meaningful way. However, critics complain that drug and device manufacturers often use their financial sponsorship to bias CME activities toward marketing their own products. Historical context Continuing medical education is not a new concept. From essentially the beginning of institutionalized medical instruction (medical instruction affiliated with medical colleges and teaching hospitals), health pra ...
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Committee On Oversight And Government Reform
The Committee on Oversight and Government Reform is the main investigative United States congressional committee, committee of the United States House of Representatives. The committee's broad jurisdiction and legislative authority make it one of the most influential and powerful panels in the House. Its chair is one of only three in the House with the authority to issue subpoenas without a committee vote or consultation with the ranking member. However, in recent history, it has become practice to refrain from unilateral subpoenas. Carolyn Maloney (Democratic Party (United States), D-New York) served as acting chair of the committee following the death of Elijah Cummings (Democratic Party (United States), D-Maryland) on October 17, 2019; she was elected chair a month later. Representative Jim Jordan served as ranking member from January 3, 2019, until March 12, 2020. On March 31, 2020, Jordan switched to become the ranking member of the Judiciary Committee instead. Representativ ...
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Hydraulic Fracturing
Fracking (also known as hydraulic fracturing, fracing, hydrofracturing, or hydrofracking) is a well stimulation technique involving the fracturing of Formation (geology), formations in bedrock by a pressurized liquid. The process involves the high-pressure injection of "fracking fluid" (primarily water, containing sand or other hydraulic fracturing proppants, proppants suspended with the aid of thickening agents) into a wellbore to create cracks in the deep-rock formations through which natural gas, petroleum, and brine will flow more freely. When the hydraulic pressure is removed from the well, small grains of hydraulic fracturing proppants (either sand or aluminium oxide) hold the fractures open. Fracking, using either hydraulic pressure or acid, is the most common method for well stimulation. Well stimulation techniques help create pathways for oil, gas or water to flow more easily, ultimately increasing the overall production of the well. Both methods of fracking are classe ...
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Fetus
A fetus or foetus (; : fetuses, foetuses, rarely feti or foeti) is the unborn offspring of a viviparous animal that develops from an embryo. Following the embryonic development, embryonic stage, the fetal stage of development takes place. Prenatal development is a continuum, with no clear defining feature distinguishing an embryo from a fetus. However, in general a fetus is characterized by the presence of all the major body organs, though they will not yet be fully developed and functional, and some may not yet be situated in their final Anatomy, anatomical location. In human prenatal development, fetal development begins from the ninth week after Human fertilization, fertilization (which is the eleventh week of Gestational age (obstetrics), gestational age) and continues until the childbirth, birth of a newborn. Etymology The word ''wikt:fetus#English, fetus'' (plural ''wikt:fetuses#English, fetuses'' or rarely, the solecism ''wikt:feti#English, feti''''Oxford English Dict ...
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Embryo
An embryo ( ) is the initial stage of development for a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres (4-cell stage) are arranged as a solid ball that when reaching a certain size, called a morula, (16-cell stage) takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts of t ...
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