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Temporins
Temporins are a family of peptides isolated originally from the skin secretion of the European red frog, ''Rana temporaria The common frog or grass frog (''Rana temporaria''), also known as the European common frog, European common brown frog, European grass frog, European Holarctic true frog, European pond frog or European brown frog or simply the frog, is a semi- ...''. Peptides belonging to the temporin family have been isolated also from closely related North American frogs, such as ''Rana sphenocephala''. Discovery In 1996, the skin of the ''Rana temporaria'' was screened into a cDNA library, discovering three peptide precursors, known as Temporin B, Temporin G, and Temporin H. Once discovered, the three peptide, along with other temporins found in the sample, were separated from secretions of the frog's skin. Biological assays were performed, revealing that all temporins, in exception of temporin D and H, exhibited antibacterial activity. It was soon discovered that o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peptide
Peptides are short chains of amino acids linked by peptide bonds. A polypeptide is a longer, continuous, unbranched peptide chain. Polypeptides that have a molecular mass of 10,000 Da or more are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. Peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyclic peptides have an N-terminal (amine group) and C-terminal (carboxyl g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rana Temporaria
The common frog or grass frog (''Rana temporaria''), also known as the European common frog, European common brown frog, European grass frog, European Holarctic true frog, European pond frog or European brown frog or simply the frog, is a semi-aquatic amphibian of the family Ranidae, found throughout much of Europe as far north as Scandinavia and as far east as the Urals, except for most of the Iberian Peninsula, southern Italy, and the southern Balkans. The farthest west it can be found is Ireland. It is also found in Asia, and eastward to Japan. The nominative, and most common, subspecies ''Rana temporaria temporaria'' is a largely terrestrial frog native to Europe. It is distributed throughout northern Europe and can be found in Ireland, the Isle of Lewis and as far east as Japan. Common frogs metamorphose through three distinct developmental life stages — aquatic larva, terrestrial juvenile, and adult. They have corpulent bodies with a rounded snout, webbed feet and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
