Tc-99m
Technetium-99m (99mTc) is a metastable nuclear isomer of technetium-99 (itself an isotope of technetium), symbolized as 99mTc, that is used in tens of millions of medical diagnostic procedures annually, making it the most commonly used medical radioisotope in the world. Technetium-99m is used as a radioactive tracer and can be detected in the body by medical equipment (gamma cameras). It is well suited to the role, because it emits readily detectable gamma rays with a photon energy of 140 keV (these 8.8 pm photons are about the same wavelength as emitted by conventional X-ray diagnostic equipment) and its half-life for gamma emission is 6.0058 hours (meaning 93.7% of it decays to 99Tc in 24 hours). The relatively "short" physical half-life of the isotope and its biological half-life of 1 day (in terms of human activity and metabolism) allows for scanning procedures which collect data rapidly but keep total patient radiation exposure low. The same characteristics make the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Technetium-99m Generator
A technetium-99m generator, or colloquially a technetium cow or moly cow, is a device used to extract the metastable isotope 99mTc of technetium from a decaying sample of molybdenum-99. 99Mo has a half-life of 66 hours and can be easily transported over long distances to hospitals where its decay product technetium-99m (with a half-life of only 6 hours, inconvenient for transport) is extracted and used for a variety of nuclear medicine diagnostic procedures, where its short half-life is very useful. Parent isotope source 99Mo can be obtained by the neutron activation (n,γ reaction) of 98Mo in a high neutron flux reactor. However, the most frequently used method is through fission of uranium-235 in a nuclear reactor. While most reactors currently engaged in 99Mo production use highly enriched uranium-235 targets, proliferation concerns have prompted some producers to transition to low-enriched uranium targets. The target is irradiated with neutrons to form 99Mo as a fission pr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Radiopharmacology
Radiopharmacology is radiochemistry applied to medicine and thus the pharmacology of radiopharmaceuticals ( medicinal radiocompounds, that is, pharmaceutical drugs that are radioactive). Radiopharmaceuticals are used in the field of nuclear medicine as radioactive tracers in medical imaging and in therapy for many diseases (for example, brachytherapy). Many radiopharmaceuticals use technetium-99m (Tc-99m) which has many useful properties as a gamma-emitting tracer nuclide. In the book ''Technetium'' a total of 31 different radiopharmaceuticals based on Tc-99m are listed for imaging and functional studies of the brain, myocardium, thyroid, lungs, liver, gallbladder, kidneys, skeleton, blood and tumors. The term ''radioisotope'', which in its general word sense, sense refers to any radioactive isotope (radionuclide), has historically been used to refer to all radiopharmaceuticals, and this usage remains common. Technically, however, many radiopharmaceuticals incorporate a radioa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Technetium
Technetium is a chemical element with the symbol Tc and atomic number 43. It is the lightest element whose isotopes are all radioactive. All available technetium is produced as a synthetic element. Naturally occurring technetium is a spontaneous fission product in uranium ore and thorium ore, the most common source, or the product of neutron capture in molybdenum ores. This silvery gray, crystalline transition metal lies between manganese and rhenium in group 7 of the periodic table, and its chemical properties are intermediate between those of both adjacent elements. The most common naturally occurring isotope is 99Tc, in traces only. Many of technetium's properties had been predicted by Dmitri Mendeleev before it was discovered. Mendeleev noted a gap in his periodic table and gave the undiscovered element the provisional name '' ekamanganese'' (''Em''). In 1937, technetium (specifically the technetium-97 isotope) became the first predominantly artificial element to be produced ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Metastable Isotope
A nuclear isomer is a metastable state of an atomic nucleus, in which one or more nucleons (protons or neutrons) occupy higher energy levels than in the ground state of the same nucleus. "Metastable" describes nuclei whose excited states have half-lives 100 to 1000 times longer than the half-lives of the excited nuclear states that decay with a "prompt" half life (ordinarily on the order of 10−12 seconds). The term "metastable" is usually restricted to isomers with half-lives of 10−9 seconds or longer. Some references recommend 5 × 10−9 seconds to distinguish the metastable half life from the normal "prompt" gamma-emission half-life. Occasionally the half-lives are far longer than this and can last minutes, hours, or years. For example, the nuclear isomer survives so long (at least 1015 years) that it has never been observed to decay spontaneously. The half-life of a nuclear isomer can even exceed that of the ground state of the same nuclide, as shown by as well as , ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nuclear Isomer
A nuclear isomer is a metastable state of an atomic nucleus, in which one or more nucleons (protons or neutrons) occupy higher energy levels than in the ground state of the same nucleus. "Metastable" describes nuclei whose excited states have half-lives 100 to 1000 times longer than the half-lives of the excited nuclear states that decay with a "prompt" half life (ordinarily on the order of 10−12 seconds). The term "metastable" is usually restricted to isomers with half-lives of 10−9 seconds or longer. Some references recommend 5 × 10−9 seconds to distinguish the metastable half life from the normal "prompt" gamma-emission half-life. Occasionally the half-lives are far longer than this and can last minutes, hours, or years. For example, the nuclear isomer survives so long (at least 1015 years) that it has never been observed to decay spontaneously. The half-life of a nuclear isomer can even exceed that of the ground state of the same nuclide, as shown by as well as , ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Powell Richards
Powell may refer to: People * Powell (surname) * Powell (given name) * Powell baronets, several baronetcies *Colonel Powell (other), several military officers * General Powell (other), several military leaders * Governor Powell (other), several governors * Justice Powell (other), several judges *Major Powell (other), several military officers * Secretary Powell (other), several officials *Senator Powell (other), several senators Places * Powell Butte (other), several hills * Powell County (other), several counties * Powell Creek (other), several watercourses * Mount Powell (other) or Powell Mountain, several mountains * Powell River (other), several watercourses * Powell Township (other), several townships Antarctica * Powell Island, South Orkney Islands Maldives * Powell Islands, Raa Atoll, Maldives United States * Powell, Alabama, a town in DeKalb County * ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brookhaven National Laboratory
Brookhaven National Laboratory (BNL) is a United States Department of Energy national laboratory located in Upton, Long Island, and was formally established in 1947 at the site of Camp Upton, a former U.S. Army base and Japanese internment camp. Its name stems from its location within the Town of Brookhaven, approximately 60 miles east of New York City. It is managed by Stony Brook University and Battelle Memorial Institute. Research at BNL includes nuclear and high energy physics, energy science and technology, environmental and bioscience, nanoscience, and national security. The 5,300 acre campus contains several large research facilities, including the Relativistic Heavy Ion Collider and National Synchrotron Light Source II. Seven Nobel Prizes have been awarded for work conducted at Brookhaven Lab. Overview BNL is staffed by approximately 2,750 scientists, engineers, technicians, and support personnel, and hosts 4,000 guest investigators every year. The laboratory has ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Highly Enriched Uranium
Enriched uranium is a type of uranium in which the percent composition of uranium-235 (written 235U) has been increased through the process of isotope separation. Naturally occurring uranium is composed of three major isotopes: uranium-238 (238U with 99.2739–99.2752% natural abundance), uranium-235 (235U, 0.7198–0.7202%), and uranium-234 (234U, 0.0050–0.0059%). 235U is the only nuclide existing in nature (in any appreciable amount) that is fissile with thermal neutrons. Enriched uranium is a critical component for both civil nuclear power generation and military nuclear weapons. The International Atomic Energy Agency attempts to monitor and control enriched uranium supplies and processes in its efforts to ensure nuclear power generation safety and curb nuclear weapons proliferation. There are about 2,000 tonnes of highly enriched uranium in the world, produced mostly for nuclear power, nuclear weapons, naval propulsion, and smaller quantities for research reac ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chien-Shiung Wu
) , spouse = , residence = , nationality = ChineseAmerican , field = Physics , work_institutions = Institute of Physics, Academia Sinica University of California at BerkeleySmith CollegePrinceton UniversityColumbia UniversityZhejiang University , alma_mater = National Central University University of California, Berkeley , doctoral_advisor = Ernest Lawrence , thesis_title = I. The Continuous X-Rays Excited by the Beta-Particles of . II. Radioactive Xenons , thesis_url = , thesis_year = 1940 , doctoral_students = , known_for = , influences = , influenced = , awards = , footnotes = , signature = Chien-Shiung Wu ( zh, t=吳健雄, p=Wú Jiànxióng, w=Wu2 Chien4-hsiung2; May 31, 1912 – February 16, 1997) was a Chinese-American particle and experimental physicist who made significant contributions in the fields of nuclear and particle physics. Wu worked on the Manhattan Project, where she helped develop the process for separating uranium into u ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lawrence Berkeley National Laboratory
Lawrence Berkeley National Laboratory (LBNL), commonly referred to as the Berkeley Lab, is a United States national laboratory that is owned by, and conducts scientific research on behalf of, the United States Department of Energy. Located in the hills of Berkeley, California, the lab overlooks the campus of the University of California, Berkeley, and is managed by the University of California system. History 1931–1941 The laboratory was founded on August 26, 1931, by Ernest Lawrence, as the Radiation Laboratory of the University of California, Berkeley, associated with the Physics Department. It centered physics research around his new instrument, the cyclotron, a type of particle accelerator for which he was awarded the Nobel Prize in Physics in 1939. Throughout the 1930s, Lawrence pushed to create larger and larger machines for physics research, courting private philanthropists for funding. He was the first to develop a large team to build big projects to make discov ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ernest Orlando Lawrence
Ernest Orlando Lawrence (August 8, 1901 – August 27, 1958) was an American nuclear physicist and winner of the Nobel Prize in Physics in 1939 for his invention of the cyclotron. He is known for his work on uranium-isotope separation for the Manhattan Project, as well as for founding the Lawrence Berkeley National Laboratory and the Lawrence Livermore National Laboratory. A graduate of the University of South Dakota and University of Minnesota, Lawrence obtained a PhD in physics at Yale in 1925. In 1928, he was hired as an associate professor of physics at the University of California, Berkeley, becoming the youngest full professor there two years later. In its library one evening, Lawrence was intrigued by a diagram of an accelerator that produced high-energy particles. He contemplated how it could be made compact, and came up with an idea for a circular accelerating chamber between the poles of an electromagnet. The result was the first cyclotron. Lawrence went on to ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |