Tariquidar
Tariquidar (INN/USAN) is a potent P-glycoprotein inhibitor and a substrate of breast cancer protein (BCRP/ABCG2) undergoing research as an adjuvant against multi-drug resistance in cancer. Tariquidar progressed to phase III clinical trials in combination with vinorelbine Vinorelbine, sold under the brand name Navelbine among others, is a chemotherapy medication used to treat a number of types of cancer. This includes breast cancer and non-small cell lung cancer. It is given by injection into a vein or by mout ... in an effort to enhance the efficacy of this chemotherapeutic agent. However, several of these trials were terminated early due to adverse effects, and further development of Tariquidar was subsequently halted. References Experimental cancer drugs Quinolines Benzanilides Norsalsolinol ethers Nicotinamides {{antineoplastic-drug-stub ...
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