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Tao Jiang (computer Scientist)
Tao Jiang () is a Chinese-Canadian computer scientist and bioinformatician. He is Distinguished Professor of Computer Science and Engineering at the University of California, Riverside and was previously Distinguished Visiting Professor at Tsinghua University and Professor of Computer Science at McMaster University. Biography Jiang received his BS degree in Computer Science from the University of Science and Technology of China, Hefei in 1984 and PhD in Computer Science in 1988 from the University of Minnesota, Twin Cities, advised by Oscar H. Ibarra. From 1989 to 2001, he was on faculty in the Department of Software at McMaster University, Hamilton, Onatario, Canada. He joined the University of California, Riverside as Professor of Computer Science and Engineering in 1999 and became Distinguished Professor of Computer Science and Engineering in 2019. Jiang worked extensively in theoretical computer science, including automata theory, formal languages, computational complexit ...
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Computer Science
Computer science is the study of computation, information, and automation. Computer science spans Theoretical computer science, theoretical disciplines (such as algorithms, theory of computation, and information theory) to Applied science, applied disciplines (including the design and implementation of Computer architecture, hardware and Software engineering, software). Algorithms and data structures are central to computer science. The theory of computation concerns abstract models of computation and general classes of computational problem, problems that can be solved using them. The fields of cryptography and computer security involve studying the means for secure communication and preventing security vulnerabilities. Computer graphics (computer science), Computer graphics and computational geometry address the generation of images. Programming language theory considers different ways to describe computational processes, and database theory concerns the management of re ...
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Approximation Algorithms
In computer science and operations research, approximation algorithms are efficient algorithms that find approximate solutions to optimization problems (in particular NP-hard problems) with provable guarantees on the distance of the returned solution to the optimal one. Approximation algorithms naturally arise in the field of theoretical computer science as a consequence of the widely believed P ≠ NP conjecture. Under this conjecture, a wide class of optimization problems cannot be solved exactly in polynomial time. The field of approximation algorithms, therefore, tries to understand how closely it is possible to approximate optimal solutions to such problems in polynomial time. In an overwhelming majority of the cases, the guarantee of such algorithms is a multiplicative one expressed as an approximation ratio or approximation factor i.e., the optimal solution is always guaranteed to be within a (predetermined) multiplicative factor of the returned solution. However, there a ...
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Fellow Of The American Association For The Advancement Of Science
Fellowship of the American Association for the Advancement of Science (FAAAS) is an honor accorded by the American Association for the Advancement of Science (AAAS) to distinguished persons who are members of the Association. Fellows are elected annually by the AAAS Council for "efforts on behalf of the advancement of science or its applications hichare scientifically or socially distinguished". Examples of areas in which nominees may have made significant contributions are research; teaching; technology; services to professional societies; administration in academe, industry, and government; and communicating and interpreting science to the public. The association has awarded fellowships since 1874. AAAS publishes annual update of active Fellows list, which also provides email address to verify status of non-active Fellows. See also :Fellows of the American Association for the Advancement of Science for more examples. AAAS Fellows AAAS Fellows include Nobel Prize winners ...
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Genetic Engineering And Biotechnology News
Mary Ann Liebert, Inc. is a publishing company founded by its president, Mary Ann Liebert, in 1980 and a subsidiary of Sage Publishing. The company publishes peer-reviewed academic journals, books, and trade magazines in the areas of biotechnology, biomedical sciences, medical research, and life sciences; clinical medicine, surgery, and nursing; technology and engineering; environmental science; public health and policy; law, regulation, and education. The company's headquarters is in New Rochelle, New York. The company has been described as the first to establish a specialty in genetic engineering. Publications Eschewing traditional market research, the publisher seeks out niche topics overlooked by larger publishers. Its portfolio of more than ninety peer-reviewed journals includes: Publications focused on topics outside of the medical field include ''Westchester Wag'', which covers the social scene in Westchester County, New York, and ''Rinkmagazine'', a skating perio ...
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RNA-Seq
RNA-Seq (named as an abbreviation of RNA sequencing) is a technique that uses next-generation sequencing to reveal the presence and quantity of RNA molecules in a biological sample, providing a snapshot of gene expression in the sample, also known as transcriptome. RNA-Seq facilitates the ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutations/ SNPs and changes in gene expression over time, or differences in gene expression in different groups or treatments. In addition to mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Seq can also be used to determine exon/intron boundaries and verify or amend previously annotated 5' and 3' gene boundaries. Recent advances in RNA-Seq include single cell sequencing, bulk RNA sequencing, 3' mRNA-sequencing, in situ sequencing of fixed tissue, and native RNA molecule sequencin ...
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Gene Isoform
In genetics, gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or untranslated regions (UTRs), potentially altering gene function. Cis-regulatory elements in the promoter contain sequences recognized by transcription factors and the basal transcription machinery. So the location of the TSS is important for understanding the biogenesis of specific isoforms. The idea that different binding partners confer different functional properties has been well studied in tissue-specific gene regulation. For example, the same transcription factor (TF) can direct gene expression in different tissues simply by binding with different TSSs in each tissue. Isoforms harboring changes in the CDS have been the most thoroughly characterized because they commonly give rise to proteins with different functional properties. UTRs regulate the levels of primary transcript in numerous ways: tra ...
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New Scientist
''New Scientist'' is a popular science magazine covering all aspects of science and technology. Based in London, it publishes weekly English-language editions in the United Kingdom, the United States and Australia. An editorially separate organisation publishes a monthly Dutch-language edition. First published on 22 November 1956, ''New Scientist'' has been available in online form since 1996. Sold in retail outlets (paper edition) and on subscription (paper and/or online), the magazine covers news, features, reviews and commentary on science, technology and their implications. ''New Scientist'' also publishes speculative articles, ranging from the technical to the philosophical. ''New Scientist'' was acquired by Daily Mail and General Trust (DMGT) in March 2021. History Ownership The magazine was founded in 1956 by Tom Margerison, Max Raison and Nicholas Harrison as ''The New Scientist'', with Issue 1 on 22 November 1956, priced at one shilling (). An article in the magazi ...
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Heilbronn Triangle Problem
In discrete geometry and discrepancy theory, the Heilbronn triangle problem is a problem of placing points in the plane, avoiding triangles of small area. It is named after Hans Heilbronn, who conjectured that, no matter how points are placed in a given area, the smallest triangle area will be at most Proportionality (mathematics)#Inverse proportionality, inversely proportional to the Square (algebra), square of the number of points. His conjecture was proven false, but the Asymptotic analysis, asymptotic growth rate of the minimum triangle area remains unknown. Definition The Heilbronn triangle problem concerns the placement of n points within a shape in the plane, such as the unit square or the unit disk, for a given Each triple of points form the three vertices of a triangle, and among these triangles, the problem concerns the smallest triangle, as measured by area. Different placements of points will have different smallest triangles, and the problem asks: how should n point ...
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Paul Vitanyi
Paul may refer to: People * Paul (given name), a given name, including a list of people * Paul (surname), a list of people * Paul the Apostle, an apostle who wrote many of the books of the New Testament * Ray Hildebrand, half of the singing duo Paul & Paula * Paul Stookey, one-third of the folk music trio Peter, Paul and Mary * Billy Paul, stage name of American soul singer Paul Williams (1934–2016) * Vinnie Paul, drummer for American Metal band Pantera * Paul Avril, pseudonym of Édouard-Henri Avril (1849–1928), French painter and commercial artist * Paul, pen name under which Walter Scott wrote ''Paul's letters to his Kinsfolk'' in 1816 * Jean Paul, pen name of Johann Paul Friedrich Richter (1763–1825), German Romantic writer Places *Paul, Cornwall, a village in the civil parish of Penzance, United Kingdom *Paul (civil parish), Cornwall, United Kingdom *Paul, Alabama, United States, an unincorporated community *Paul, Idaho, United States, a city *Paul, Nebraska, United Sta ...
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Ming Li
Ming Li is a Canadian computer scientist, known for his contributions to Kolmogorov complexity, bioinformatics, machine learning theory, and analysis of algorithms. Li is currently a university professor at the David R. Cheriton School of Computer Science at the University of Waterloo. He holds a Tier I Canada Research Chair in Bioinformatics. In addition to academic achievements, his research has led to the founding of two independent companies. Education Li received a Master of Science degree (Computer Science) from Wayne State University in 1980 and earned a Doctor of Philosophy degree (Computer Science) under the supervision of Juris Hartmanis, from Cornell University in 1985. His post-doctoral research was conducted at Harvard University under the supervision of Leslie Valiant. Career Paul Vitanyi and Li pioneered Kolmogorov complexity theory and applications, and co-authored the textbook ''An Introduction to Kolmogorov Complexity and Its Applications''. In 2000, Li found ...
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Alternative Splicing
Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative RNA splicing, splicing process during gene expression that allows a single gene to produce different splice variants. For example, some exons of a gene may be included within or excluded from the final RNA product of the gene. This means the exons are joined in different combinations, leading to different splice variants. In the case of protein-coding genes, the proteins translated from these splice variants may contain differences in their amino acid sequence and in their biological functions (see Figure). Biologically relevant alternative splicing occurs as a normal phenomenon in eukaryotes, where it increases the number of proteins that can be encoded by the genome. In humans, it is widely believed that ~95% of multi-exonic genes are alternatively spliced to produce functional alternative products from the same gene but many scientists believe that most of the observed splice variants ar ...
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