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TWEETIO (psychedelics)
TWEETIO is a family of phenethylamine psychedelic drugs. They are analogues of the 2C drugs (4-substituted 2,5-dimethoxyphenethylamines) in which one or both of the methoxy groups at positions 2 and 5 of the phenyl ring have been lengthened to ethoxy groups. Examples include 2CD-2-ETO (a TWEETIO of 2C-D), 2CE-5-ETO (a TWEETIO of 2C-E), and 2CT2-5-ETO (a TWEETIO of 2C-T-2). The TWEETIO drugs are said to have been named in a humorous way by pronouncing the simplest structural form of "2-EtO-X". Limited human data are available on the TWEETIO compounds. In any case, some generalizations have been made, including that the 2-ETO compounds tend to have a shorter duration and decreased potency, the 5-ETO drugs tend to have enhanced potency and remarkably increased durations, and the 2,5-Di-ETO drugs tend to be inactive. The TWEETIO compounds were not the work of psychedelic chemist Alexander Shulgin, but were communicated to and reported by Shulgin in the scientific literature i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and pharmacology of such agents—in his mid-life and later, many through preparation in his home laboratory, and testing on himself. He is acknowledged to have introduced to broader use, in the late 1970s, the previously-synthesized compound MDMA ("ecstasy"), in research psychopharmacology and in combination with conventional therapy, the latter through presentations and academic publications, including to psychologists; and for the rediscovery, occasional discovery, and regular synthesis and personal use and distribution, of possibly hundreds of Psychoactive drug, psychoactive compounds (for their Psychedelic drug, psychedelic and MDMA-like empathogenic bioactivity, bioactivities). As such, Shulgin is seen both as a pioneering and a controversi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2CT2-DI-ETO
CT or ct may refer to: In arts and media * ''c't'' (''Computer Technik''), a German computer magazine * '' Carrick Times'', Northern Irish newspaper * Freelancer Agent Connecticut (C.T.), a fictional character in the web series ''Red vs. Blue'' * Christianity Today, an American evangelical Christian magazine Businesses and organizations * CT Corp, an Indonesian conglomerate * CT Corporation, an umbrella brand for two businesses: CT Corporation and CT Liena * C/T Group, formerly Crosby Textor Group, social research and political polling company * Canadian Tire, a Canadian company engaged in retailing, financial services and petroleum * Calgary Transit, the public transit service in Calgary, Alberta, Canada * Central Trains (National Rail abbreviation), a former train operating company in the United Kingdom * Czech Television, the public television broadcaster in the Czech Republic * Community Transit, the public transit service in Snohomish County, Washington, U.S. * Comunión ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2CD-5-ETO
2CD-5EtO is a homologue of the psychedelic phenethylamine 2C-D, where the 5-methoxy group of 2C-D has been lengthened to an ethoxy group. 2CD-5EtO is a representative example of the so-called " tweetio" compounds discovered by Alexander Shulgin and briefly mentioned in his book ''PiHKAL''. They are homologues of the 2C family of drugs, where either one or both of the methoxy groups at the 2,5-positions of the aromatic ring have been replaced by ethoxy. The term tweetio was derived phonetically from the sound of the "2-ETO" derivatives. Many tweetio derivatives of various 2C drugs have been synthesized and tested, including the 2-ethoxy homologues 2CD-2EtO, 2CB-2EtO, 2CI-2EtO, 2CT-2EtO, 2CT2-2EtO, 2CT4-2EtO and 2CT7-2EtO, the 5-ethoxy homologues 2CD-5EtO, 2CE-5EtO, 2CB-5EtO, 2CT-5EtO and 2CT2-5EtO, and the 2,5-diethoxy homologues 2CD-diEtO, 2CB-diEtO and 2CT2-diEtO, as well as 2CE-5iPrO. In general, the 2-ethoxy homologues were all several times less potent and somewhat short ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ASR-2001
ASR-2001, also known as 2CB-5PrO or as 4-bromo-2-methoxy-5-propoxyphenethylamine, is a non-hallucinogenic serotonin receptor agonist of the phenethylamine, 2C, and TWEETIO families which is under development for the treatment of psychiatric disorders. It is the TWEETIO analogue of 2C-B in which the 5-methoxy group is replaced with a 5- propoxy group. The drug is a non-hallucinogenic serotonin 5-HT2A receptor agonist and is orally active, highly potent, and has high selectivity over the serotonin 5-HT2B receptor (94-fold in terms of activational potency). It is also a highly potent agonist of the serotonin 5-HT1B receptor, whereas its activity at the serotonin serotonin 5-HT1A receptor was very weak and its activity at the serotonin 5-HT2C receptor was not described. ASR-2001 showed no significant activity at a variety of other sites, including other serotonin receptors and the monoamine transporters. The drug is said to have low efficacy in terms of serotonin 5-HT2A rec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
